Protein Alignment CG31792 and Abcc12

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_766500.3
• Gene: Abcc12 / 244562
• MGIID: 2441679
• Length: 1366
• Species: Mus musculus
• Alignment Length: 1367
• Identity: 445/1367 - (32%)
• Similarity: 730/1367 - (53%)
• Gaps: 130/1367 - (9%)

  Fly     9 LPENPRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCS-SWANELE-T 71
            |..||.:.:.:.|..:|.:..|..|:..|.|| ..|....|..:.:..:..|... .|..|:: .
Mouse    41 LAPNPVDDAGLLSFATFSWLTPVMIRSYKHTL-TVDTLPPLSPYDSSDINAKRFQILWEEEIKRV 104

  Fly    72 NKKNASLLRVLFRVFGRYFVFLGLV--LFCLEVILTVQPMFLM-KLISSFSNPSPTSNGVAYAYA 133
            ..:.|||.||::: |.|..|.:.:|  :.|: |:..:.|..|: :::...::.|....|:
Mouse   105 GPEKASLGRVVWK-FQRTRVLMDVVANILCI-VMAALGPTVLIHQILQHITSISSGHIGI----- 162

  Fly   134 GGVILGSAL-----KVILMNPYSFAVTH-LGLKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINL 192
             |:.|..||     ..:|....::|:.: ..::::|.:|::|:...|.. || |..||.|.::|:
Mouse   163 -GICLCLALFTTEFTKVLFWALAWAINYRTAIRLKVALSTLIFENLLSF-KT-LTHISAGEVLNI 224

  Fly   193 ISNDLGRMDTFIQFTHYLWLAPLQA----LMVTYLMYQ--EIGIAAVFGMTFILLFIPLQMYLGK 251
            :|:     |::..|...|: .||.|    |||...:|.  .:|..|:.|::..|:|||:||::.|
Mouse   225 LSS-----DSYSLFEAALF-CPLPATIPILMVVCAVYAFFILGSTALVGISVYLIFIPIQMFMAK 283

  Fly   252 KISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINSIRHVAYAKCLIW 316
            ..|..|......:|||::.|.|.:..|::|||||||..|...:...|.:|...:....|    :.
Mouse   284 LNSTFRRSAISVTDKRVQTMNEFLTCIKLIKMYAWEESFINTIHDIRKREKKLLEKAGY----VQ 344

  Fly   317 SFNRFLTPVSIFLSLVG----FVLMGRFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVS 377
            |.|..|.|:...:::|.    .:.:.|.|||.|||.:.|.:||::.:: |.....|...||..||
Mouse   345 SGNSALAPIVSTIAIVSTFTCHIFLKRKLTAPVAFSVIAMFNVMKFSI-AILPFSVKAVAEASVS 408

  Fly   378 IKRVQKLLLS---GEVVAKDEN-----VVSNGA---EEDLQEARE--KLLVTPTPMRAPEKPPHN 429
            ::|::|:|::   ...:.:.|:     :::|..   |:::....:  |..:....:...::|...
Mouse   409 LRRMKKILIAKSPPSYITQPEDPDTILLLANATLTWEQEINRKSDPPKAQIQKRHVFKKQRPELY 473

  Fly   430 SEDCVSISELKA-KWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEI 493
            ||...|...:.: :|.:.||...|..::..|..|.::.|.|:.||||||||.|:||:::::.|.:
Mouse   474 SEQSRSDQGVASPEWQSGSPKSVLHNISFVVRKGKVLGICGNVGSGKSSLISALLGQMQLQKGVV 538

  Fly   494 EVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGAS 558
            .|.|.::|.||:.|:|.|.||:|||||:..:.:||...|..|.|::|...||..|.|.:|:||.:
Mouse   539 AVNGPLAYVSQQAWIFHGNVRENILFGEKYNHQRYQHTVHVCGLQKDLNSLPYGDLTEIGERGVN 603

  Fly   559 LSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQ 623
            |||||:.||||||:||.:..:|||||||||||:.|.:.:||||::..|:.|.|:|||||||||:.
Mouse   604 LSGGQRQRISLARAVYANRQLYLLDDPLSAVDAHVGKHVFEECIKKTLKGKTVVLVTHQLQFLES 668

  Fly   624 ADQIVIMEMGKVKAVGTYESLHKS------------GLDF-------GIVLDDPVNDNEAAEDRS 669
            .|:::::|.|::...||::.|.:.            ||.|       .:.:.:.:.::.|..|..
Mouse   669 CDEVILLEDGEICEKGTHKELMEERGRYAKLIHNLRGLQFKDPEHIYNVAMVETLKESPAQRDED 733

  Fly   670 RTSSITDQRRSSVKSVLSHAESCPEDVGEE--------------QKINLQRQQLGRNGLGVYVDY 720
            ...:..|::                |.|:|              |.|..:..|.|......|..|
Mouse   734 AVLASGDEK----------------DEGKEPETEEFVDTNAPAHQLIQTESPQEGIVTWKTYHTY 782

  Fly   721 FRAGGGFLSFSVVMTFFVCSQGLASLGDYFLSPWVSRNEKMVA---HNYTTDAKDADFEMHAAYI 782
            .:|.||:|...:|:..|....|.::...::|..|:.|..::|.   :|.|....|...:....::
Mouse   783 IKASGGYLVSFLVLCLFFLMMGSSAFSTWWLGIWLDRGSQVVCASQNNKTACNVDQTLQDTKHHM 847

  Fly   783 YMLITVLS----IMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKD 843
            |.|:.:.|    :|..|.:.|.|.|..:.||..|||.:|..|.|:.|.||:..|.|.::||||||
Mouse   848 YQLVYIASMVSVLMFGIIKGFTFTNTTLMASSSLHNRVFNKIVRSPMSFFDTTPTGRLMNRFSKD 912

  Fly   844 MGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLE 908
            |.::|..||......:|.|.:....::::|.|.|:.|:......::...|...:.:...::|::|
Mouse   913 MDELDVRLPFHAENFLQQFFMVVFILVIMAAVFPVVLVVLAGLAVIFLILLRIFHRGVQELKQVE 977

  Fly   909 ASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIF--C 971
            ..:|||.:||..:|:.||..|.|:.......::|....|.:||....|....|.||..|||.  .
Mouse   978 NISRSPWFSHITSSIQGLGVIHAYDKKDDCISKFKTLNDENSSHLLYFNCALRWFALRMDILMNI 1042

  Fly   972 VLFIA--MITLSFFIFPPSSAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEY-EEI 1033
            |.|:.  ::|||   |...||:..||:::..:.|:|.:|..||...|.:....|.|.:.|| ...
Mouse  1043 VTFVVALLVTLS---FSSISASSKGLSLSYIIQLSGLLQVCVRTGTETQAKFTSAELLREYILTC 1104

  Fly  1034 EPE--GPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTG 1096
            .||  .|.:.....|   .||.:|:|.|.:..:||..  .:..||..|:..|:..:.||||||||
Mouse  1105 VPEHTHPFKVGTCPK---DWPSRGEITFKDYRMRYRD--NTPLVLDGLNLNIQSGQTVGIVGRTG 1164

  Fly  1097 AGKSSLINALFRL-SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYS 1160
            :|||||..||||| ....|::.||:.|...:||.|||:|:::|||:||||.||||:||||...::
Mouse  1165 SGKSSLGMALFRLVEPASGTIIIDEVDICTVGLEDLRTKLTMIPQDPVLFVGTVRYNLDPLGSHT 1229

  Fly  1161 DDRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANV 1225
            |:.||..||...::|.:..:...|:.::||.|.|||||:|||:|:|||:||:::|:::|||||::
Mouse  1230 DEMLWHVLERTFMRDTIMKLPEKLQAEVTENGENFSVGERQLLCMARALLRNSKIILLDEATASM 1294

  Fly  1226 DPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQD 1290
            |.:||.|:|:||:..|:.|||||:||||:|:::.|.||||:.|:|:||..| |:|.....:||..
Mouse  1295 DSKTDTLVQSTIKEAFKSCTVLTIAHRLNTVLNCDLVLVMENGKVIEFDKP-EVLAEKPDSAFAM 1358

  Fly  1291 LV 1292
            |:
Mouse  1359 LL 1360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	445/1367 (33%)
Abcc12	NP_766500.3	MRP_assoc_pro	43..1366	CDD:188098	444/1365 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	470..492		5/21 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	726..749		6/38 (16%)