| Sequence 1: | NP_001260548.1 | Gene: | CG31792 / 35163 | FlyBaseID: | FBgn0051792 | Length: | 1323 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001028508.2 | Gene: | Abcc4 / 239273 | MGIID: | 2443111 | Length: | 1325 | Species: | Mus musculus |
| Alignment Length: | 1345 | Identity: | 561/1345 - (41%) |
|---|---|---|---|
| Similarity: | 825/1345 - (61%) | Gaps: | 76/1345 - (5%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 8 DLPENPRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSWANELETN 72
Fly 73 KKNA---SLLRVLFRVFGRYFVFLGLVLFCLEVILTVQPMFLMKLISSFSNPSPTSN---GVAYA 131
Fly 132 YAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISND 196
Fly 197 LGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTA 261
Fly 262 IRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINSIRHVAYAKCLIWSFNRFLTPVS 326
Fly 327 IFLSLVGFVLMGRFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQKLLLSGEVV 391
Fly 392 AKDENVVSNGAEEDLQEAREKLLVTPTPMRAPEKPPHNSEDCVSISELKAKWTTNSPDYTLSGVN 456
Fly 457 LQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQEPWLFSGTVRQNILFGQ 521
Fly 522 PMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLLDDPL 586
Fly 587 SAVDSSVARRLFEECLRGHLRDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESLHKSGLDF 651
Fly 652 GIVLDDPVNDNEAAEDRSRTSSITDQRRS-SVKSVLSHAESCP---------EDVGEEQKINLQR 706
Fly 707 QQL-GRNGLGVYVDYFRAGGG--FLSFSVVM-----TFFVCSQGLASLGDYFLSPWVSR----NE 759
Fly 760 KMVAHNYTTDAKDADFEMHAAYIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRAS 824
Fly 825 MYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIV 889
Fly 890 IYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASY 954
Fly 955 MFISTSRAFAYWMDIFCVLFIAMITLSFFIFPPS-SAADVGLAITQAMGLTGTVQWTVRQSAELE 1018
Fly 1019 NTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVI 1083
Fly 1084 KPKEKVGIVGRTGAGKSSLINALFRLSYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGT 1148
Fly 1149 VRHNLDPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVCLARAILRDN 1213
Fly 1214 RILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYE 1278
Fly 1279 LLTADDTNAFQDLVKQTGQATYDTLLKISQREFEKSEKPSLMLPS 1323 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG31792 | NP_001260548.1 | CFTR_protein | 12..1281 | CDD:273530 | 553/1297 (43%) |
| ABC_membrane | 94..360 | CDD:294371 | 100/268 (37%) | ||
| ABCC_MRP_domain1 | 434..634 | CDD:213217 | 104/199 (52%) | ||
| ABC_membrane | 736..980 | CDD:294371 | 101/247 (41%) | ||
| ABCC_MRP_domain2 | 1055..1276 | CDD:213211 | 136/220 (62%) | ||
| Abcc4 | NP_001028508.2 | PLN03130 | 12..1284 | CDD:215595 | 557/1318 (42%) |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 657..690 | 6/32 (19%) | |||
| PDZ-binding. /evidence=ECO:0000250|UniProtKB:O15439 | 1322..1325 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167841675 | |
| Domainoid | 1 | 1.000 | 232 | 1.000 | Domainoid score | I2403 |
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0054 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H74563 | |
| Inparanoid | 1 | 1.050 | 1109 | 1.000 | Inparanoid score | I229 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG51855 | |
| OrthoDB | 1 | 1.010 | - | - | D138195at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001028 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42331 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_100026 | |
| Panther | 1 | 1.100 | - | - | O | PTHR24223 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X771 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 14 | 13.810 | |||||