Protein Alignment CG31792 and mrp-8

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_499598.2
• Gene: mrp-8 / 190710
• WormBaseID: WBGene00003414
• Length: 1461
• Species: Caenorhabditis elegans
• Alignment Length: 1373
• Identity: 439/1373 - (31%)
• Similarity: 704/1373 - (51%)
• Gaps: 146/1373 - (10%)

  Fly     7 EDLPENPRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSWANELET 71
            :.:.:.|.|:|:..|.:.|.:..|....|.|..|..:.|:...:...:|.|..:    |..|.:.
 Worm   171 QKIEQTPEEKSSFLSKIFFCWLNPLIRAGAKQPLTNESLHNLNENATSEWLYTR----WRAEFDK 231

  Fly    72 NKK-----NASLLRVLFRVFGRYFVFLGLVLFCLEVILTVQPMFLMKLISSFS-NPSPTSNGVAY 130
            .|.     ..|::....|:.....:.|.|.....:::..:.|:.|.:||...| :..|.|.|:|.
 Worm   232 EKAGRKSGETSIVWPFIRIQRATIITLTLARLTADIVHYLNPILLKQLIDYVSLHDQPLSFGIAI 296

  Fly   131 AYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISN 195
            |..  :...|..:.:|.|.....:....:..:..:|:.|..|.|||:.:.....:.|.|:|..:.
 Worm   297 ACI--MFSCSTTRSLLQNYQIAGMCRQAVYYQTVLSNAILHKILRLSPSARSNRTAGEILNHAAV 359

  Fly   196 DLGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKT 260
            |:..:...:.:...:|..|.|..:...::...:|.||:.|:..::|||||.:...:.|...:.|.
 Worm   360 DIEIIVHSVPYLQNMWSVPFQVTLAMTMLAITLGWAAMAGVCIMILFIPLNLCTSRFIKLSQQKQ 424

  Fly   261 AIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINSIRHVAYAKCLIWSFNRFLTPV 325
            ....|:|.::..|::.||:|:|:||||..||..:...|.||:..:|:|    |::..........
 Worm   425 MKIKDERTKLSNEMLNGIKVVKLYAWEESFEDQINRLRAKEVKMLRNV----CILSRIVDVANAA 485

  Fly   326 SIFLSLVG----FVLMG---RFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQK 383
            |.||..:|    :||..   ..||..|||:....:|.:|..|....:: :....:..||.||:::
 Worm   486 SPFLVAIGSFTCYVLWSPDENGLTPSVAFVALTIFNQLRQPMRMVANL-INTLVQARVSNKRLRQ 549

  Fly   384 LLLSGEVVAKDENVVSNGAEEDLQEAREKLLV---TPTPMRAPEKPPHNSEDCVSISELKAKWTT 445
            .|...|:..|.|..:.|.            :|   .....:.|:.||
 Worm   550 FLNDEEMERKTEVALGNA------------IVFKNASLNWKGPQNPP------------------ 584

  Fly   446 NSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQEPWLFS 510
                 .|..::..:..|.|:||||..|.|||||:.|:|.|:.:..|.::|.||::|..|..|:|:
 Worm   585 -----VLKDLSATIKPGQLIAIVGSVGGGKSSLLSAVLDEMVLLDGRVKVGGSIAYVPQHSWIFN 644

  Fly   511 GTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYR 575
            .|:::|||||..:....||.||..|.|:.||......:.|::|:.|.:|||||||||||||:||:
 Worm   645 KTIKENILFGNELSNYFYDQVVGSCQLKTDFRHFQQGENTMVGENGITLSGGQKARISLARAVYQ 709

  Fly   576 DASIYLLDDPLSAVDSSVARRLFEECL--RGHLRDKIVILVTHQLQFLQQADQIVIMEMGKVKAV 638
            |..||||||||||||:.|.|.||::.:  .|.||.|..:||||.||:.:..|.|.::|.|::...
 Worm   710 DKDIYLLDDPLSAVDAHVGRALFDKVIGPDGLLRSKTRVLVTHNLQYTKYVDTIYVIEDGQIVQH 774

  Fly   639 GTYESLHKSGLDFGIVLDDPVN-DNEAAEDRSRTS--SITD-------------QRRSSVKSVLS 687
            |::|.:......||.:..:..| |.:.|::.:.:|  |:|.             ::.|.:....|
 Worm   775 GSFEDIAYVDGPFGRLWSECENSDEDVADEEAESSEASVTPPVPVLENGDNGAIEKSSQIDRTNS 839

  Fly   688 H-AESCPEDVGEEQKI--NLQRQQLGRNGLGVYVDYFRAGGGFLSFSVVMTFFVCSQGLASLGDY 749
            | :|...:...:.||:  |::..||||....||..|.:..|.|.| |..:.||:....:..:...
 Worm   840 HFSEKSRKSEEKPQKVEKNVENVQLGRVKKSVYQLYIKTMGIFNS-SAFLIFFIAHFTVMIMRSL 903

  Fly   750 FLSPWVSRNEKM-------VAHNYTTDAKDADFEMHAAYIY--------MLITVLSIMV-TIKRS 798
            :||.|.:.|..:       |.:..:|.:.|....:....|.        ||:..|:..| ||.
 Worm   904 WLSDWSNENAAIKKATLSSVDYLNSTSSVDGPVSVETRLIVYAGFGGLEMLLLALAFTVLTIG-- 966

  Fly   799 FLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIM---TVIQ 860
                  ::|||..||:.:...:..|.:.||:..|.|.|:||.|:|:..:|::...|.|   |::.
 Worm   967 ------SLRASYGLHSPLIHALLVAPISFFDTTPTGRIINRLSRDLDVIDKLQDNIRMCTQTLLN 1025

  Fly   861 DFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNG 925
            ..::    :::|:|..|:||:.|....::.|::..:|:.||..:||||::.|||:.|..|.|::|
 Worm  1026 ACMI----LVLISISTPIFLVCAAPLILIYYFVMIYYIPTSRQLKRLESANRSPILSTIAESIHG 1086

  Fly   926 LSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIF---CVLFIAM-ITLS--FFI 984
            .|:||||..............|..:...|:...::|..|..:::.   ||||.:: .|||  :|.
 Worm  1087 ASSIRAFDKTERTTTALSTNVDKFAQCRYLSHMSNRWLATRLELLGNTCVLFASLSATLSTKYFG 1151

  Fly   985 FPPSSAADVGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHE 1049
            ..|..|   ||:::.|:.:|..:...||..:|:|:.::||||:.||:::|||.|.......:..|
 Worm  1152 LTPGMA---GLSVSYALTITEVLNICVRSVSEIESNIVSVERVNEYQKLEPEAPWRIEKSLENEE 1213

  Fly  1050 SWPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYND- 1113
            .||.:||||....|:||...|  ..|||::...|:..|::|::||||:|||||..||:|:...:
 Worm  1214 KWPVKGKIELDGFSMRYRKNL--PLVLKNIDLKIEGGERIGVIGRTGSGKSSLTMALYRMIEGES 1276

  Fly  1114 GSVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVA 1178
            |:::|||.:.:.:|||.||||:.|||||||:||||:|.|||||::||||::|..||..:||....
 Worm  1277 GTIKIDDVEIDTIGLHQLRSKLIIIPQEPVVFSGTLRFNLDPFNQYSDDQIWNCLEICQLKQFAQ 1341

  Fly  1179 SVATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRE 1243
            .....|:..|.|||.|.|||:|||:||.||:||..||:::|||||:||..||.::|..||..|.:
 Worm  1342 EDDKTLDRYIAEGGKNMSVGERQLLCLCRALLRGARIVILDEATASVDTVTDGIVQRAIRQHFPQ 1406

  Fly  1244 CTVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTGQATYDTLLKISQ 1308
            .|.:::||||.||:||||::|:|||||.||.||..||...|             :.|..||.
 Worm  1407 STTISIAHRLDTIVDSDRIVVLDAGRVAEFDTPSNLLLNPD-------------SLYSQLLN--- 1455

  Fly  1309 REFEKSEK 1316
               ||:.|
 Worm  1456 ---EKNRK 1460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	436/1368 (32%)
mrp-8	NP_499598.2	MRP_assoc_pro	177..1451	CDD:188098	433/1350 (32%)