Protein Alignment CG31792 and haf-8

DIOPT Version :9

• Sequence 1: NP_001260548.1
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_502776.1
• Gene: haf-8 / 190369
• WormBaseID: WBGene00001818
• Length: 633
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 135/555 - (24%)
• Similarity: 252/555 - (45%)
• Gaps: 82/555 - (14%)

  Fly   784 MLITVLSIMVTIKRSFLFFNLAMRASIQLHN---SMFRGISRASMYFFNKNPAGSILNRFSKDMG 845
            :|:.::.......:|..:|.:.....:...|   .:||.|....:.||::|..|.:::|.:.|..
 Worm    99 LLLALIQFSEATCKSACYFFMQYAEKLTARNIRIQLFRSILHQEISFFDENKTGQLVSRITHDSE 163

  Fly   846 QVDEMLPTIIMTVIQDFLLFGGNI-IVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEA 909
            .:...||..|.|::.:..:|.|:| |:......|.|...:.|.|.:...|.:    .|.|::|..
 Worm   164 SISNTLPVHIETLVNNLFMFFGSIPIMFCYSWQLTLTSFIEFPITLLMTRYY----GLAVEKLSE 224

  Fly   910 STRSPVYSHFAAS-------LNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFA--- 964
            ......    |||       |:.:.|:|:|.|     ..|:..:...::..:..|||.....
 Worm   225 KENDAT----AASNETVEEVLSAIRTVRSFAA-----ENFEQKRYTKNTEDWFKISTKTVTLGTI 280

  Fly   965 ---YW------MDIFCVLF------------IAMITLSFFIFPPSSA----ADVGLAITQAMGLT 1004
               :|      .|:...|:            .|::|..|:.:...:|    :.:...:.:.:||:
 Worm   281 YNYFWALMLRSQDVIRYLYGGYLALNGRMAPEALLTFIFYHWRLHTAINAFSSLFSGVMKTIGLS 345

  Fly  1005 GTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPY 1069
            ..|...:.:..:|:         .::....||                .||||||..:...| |.
 Worm   346 RKVIHLINRKPQLD---------YDFGTETPE----------------IQGKIEFEVVEFAY-PT 384

  Fly  1070 LKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYNDGSVRI--DDKDTNDMGLHDLR 1132
            .|:.:|:..::..|:..:.|.:||.:|.|||:|: :|.:..|...|.||  |.....::......
 Worm   385 RKTVNVINGINLSIESGKTVALVGPSGNGKSTLV-SLIQQFYTPQSGRILTDGIPIQNINHQHYH 448

  Fly  1133 SKISIIPQEPVLFSGTVRHN-LDPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFS 1196
            |.|:::.|||.|||||:|.| |...:..:::.:..|.|...:.:.|:.:..|.:||..|.|...|
 Worm   449 SNIALVAQEPTLFSGTIRENILFGIENGTEEAMLKAAEMANVHEFVSKMDDGYDTKCGEKGVQMS 513

  Fly  1197 VGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDR 1261
            .||:|.:.:|||::|:.|:|::||||:.:|.:::.::|..:....:|.||:.:||||.|:..:.:
 Worm   514 GGQKQRIAIARALIRNPRVLILDEATSALDSESEGMVQEALNKCAKERTVIVIAHRLSTVRKAQK 578

  Fly  1262 VLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTG 1296
            :.|::.|.|.|.|...||:...|...::.:.||.|
 Worm   579 IAVIENGSVKEMGCHDELMENQDGLYYKLVSKQLG 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_001260548.1	CFTR_protein	12..1281	CDD:273530	131/538 (24%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	434..634	CDD:213217
		ABC_membrane	736..980	CDD:294371	45/230 (20%)
		ABCC_MRP_domain2	1055..1276	CDD:213211	74/223 (33%)
haf-8	NP_502776.1	MdlB	42..613	CDD:224055	134/553 (24%)
		ABC_membrane	63..318	CDD:279056	46/231 (20%)
		ABC_MTABC3_MDL1_MDL2	373..611	CDD:213216	75/239 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000