Protein Alignment CG31792 and mrp-3

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_001359552.1
• Gene: mrp-3 / 181677
• WormBaseID: WBGene00003409
• Length: 1505
• Species: Caenorhabditis elegans
• Alignment Length: 1386
• Identity: 435/1386 - (31%)
• Similarity: 691/1386 - (49%)
• Gaps: 185/1386 - (13%)

  Fly    13 PRERSNIFS-ALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSWANELE------ 70
            |.|.:|..| .|..|:| .....|.:.||.|.|::....:...|.|..:..:.|..:.|
 Worm   194 PEENANFISRQLLLWFT-QIISLGYERTLVADDVFEMDSQMDQEYLKARWKTEWLKQTEKAREKQ 257

  Fly    71 -----------TNKKNASLL---------------RVL--------------FRVFGRYFVFLGL 95
                       |..:.|.||               ||:              :.:.|..|
 Worm   258 VKLDDKRERARTGSEKAPLLGTFNNYGAVNLDDKDRVIVQPSVIVTLWQIMKWEILGGSF----- 317

  Fly    96 VLFCLEVILTVQPMFLMKLISSFSNP-SPTSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGL 159
            :.|..:::....|.||..||.....| :|..||:..|.  |:.|...:|.:.||.|..|:|.:|.
 Worm   318 IKFLSDLLQFANPTFLNYLILFIETPNAPLINGIGLAV--GLFLAGQIKSLFMNTYFIAMTRVGA 380

  Fly   160 KIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLM 224
            ||:..:|..:|.|.|.|:.|...|.:.|.::|::|.|:.|...........|.:|.|.::...|:
 Worm   381 KIQTMLSCAVYEKSLLLSNTARRERTVGEMVNILSIDVDRFRMITPQIQQYWSSPFQIIICMVLL 445

  Fly   225 YQEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELP 289
            .|.||:|...|:..::..:|:.:.:.......:|:.....|:|:|::.|::.||:|:|:.|||..
 Worm   446 SQTIGVAVWAGIVVMISIVPINICVSMITKRWQLRLMKYKDERIRLINEVLNGIKVVKLSAWETA 510

  Fly   290 FEKMVAHARHKEINSIRHVA----YAKCLIWSFNRFLTPVSIFL-SLVGFVLMG--RFLTAEVAF 347
            .|:.:...|.||:..|:..|    :|.||     ....||.:.| |...|||:.  ..||..:||
 Worm   511 MEETIERVRDKELKMIKQSALLKTFADCL-----NVGAPVFVALSSFTVFVLIDPKNVLTPNIAF 570

  Fly   348 LITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQKLLLSGEVVAKDENVVSNGAEEDLQEAREK 412
            :..:.:|::|..:.....: |.||.:.:||.|||:..|...||   |...:.       :|.|.:
 Worm   571 VSLSLFNLLRGPLMMAAEL-VAQTVQLVVSNKRVRTFLCEKEV---DTAAID-------KEIRGE 624

  Fly   413 LLVTPTPMRAPEKPPHNSEDCVSISELKAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSS 477
            |..                :.|.|......| .::....||.:.....:..||.:||..||||||
 Worm   625 LYT----------------NTVEIHSGSFAW-DSAEARILSDIEFLAGSKELVTVVGSVGSGKSS 672

  Fly   478 LIQAILGELRVESGEIEVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFE 542
            |:.|.|||:....|.:.|.||::|.||:||:.:.::::|:|....::...|..|:..|||:.|.:
 Worm   673 LLLAALGEMEKVCGYVGVRGSVAYLSQQPWILNQSLKKNVLMQADLNDVLYKKVIESCALKEDLK 737

  Fly   543 LLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECL--RGH 605
            .||..|.|.:|::|.:|||||||||:|||:||:...:|.|||||||||:.|.:.:|:..:  .|.
 Worm   738 QLPDGDDTEIGEKGINLSGGQKARIALARAVYQSKDVYFLDDPLSAVDAHVGKHIFDNVIGPNGM 802

  Fly   606 LRDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESL---------------------HKSGL 649
            |.....||||:...|||::.:|::|:.|::|..|||..|                     ..||.
 Worm   803 LSHTTRILVTNCTSFLQESGKIIVMKDGRIKHCGTYNELLTDVEAREYLQEVDNEYAQAQESSGE 867

  Fly   650 DFG-----IVLDDPVNDNEAAEDRSRTSSITDQRRSSVKSVLSHAESCPEDVGEEQK----INLQ 705
            :.|     .:|...:.........||.|.|:  |:.|..|::           |::|    |..:
 Worm   868 ESGGEENSDILPGSIASGSRMSRLSRLSKIS--RKKSKSSIV-----------EKKKPDALITKE 919

  Fly   706 RQQLGRNGLGVYVDYFRAGGGFLSFSVVMTFFVCSQGLASLG-DYFLSPWVSRNEKMVAHNYTTD 769
            ...:||...|||:.||:| .|.:::.:.....|......:|| ..:|:.|...|  :..::..|.
 Worm   920 EAAIGRVNPGVYLLYFKA-MGIVTYVLPYAIAVVLNVSFALGRSLWLTAWSDAN--IDINHPDTM 981

  Fly   770 AKDADFEMHAAYIYMLITVLSIMVTIKRSFLFFNLAM------RASIQLHNSMFRGISRASMYFF 828
            :..|...::|.:        .|...|   ||||:|.:      .||..||..:...:.|..:.:|
 Worm   982 SVGARLGVYAGF--------GITEVI---FLFFSLVLLLIGGVAASKNLHKPLLHNVLRNPLSYF 1035

  Fly   829 NKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYL 893
            :..|.|.|:||.:|||..||..|.:....::...:.....:::::...|||:...:...|:.:::
 Worm  1036 DITPIGRIINRLAKDMEVVDLRLSSSFRFLVMALINMVQTVLIVSYTTPLFIAIIIPVFIIYFFV 1100

  Fly   894 RSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFIS 958
            ..:.:|::..::|:.:.||||::|:|:.:|.|:||:|||..........|.:.:.|...||....
 Worm  1101 LKYSIKSTRQLQRIASLTRSPIFSNFSETLQGISTVRAFQWSDEFVRRNDEHLNTHVKCSYYSQM 1165

  Fly   959 TSRAFAYWMD----------IFCVLFIAMITLSFFIFPPSSAADVGLAITQAMGLTGTVQWTVRQ 1013
            .:|    |:.          ||....:|:|.....|    :|..:||:::.::.:|..:...|||
 Worm  1166 ANR----WLSIRLELLGNIVIFSAAILAIIGKESGI----TAGMLGLSVSYSLNITFMLNMFVRQ 1222

  Fly  1014 SAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESVLKS 1078
            ..|:|..::||||:.||.:.:.|.......:..| .:||..|.:...:.|.||...|  :.|||.
 Worm  1223 INEVETNVVSVERIDEYSKTKSEAEWRLDNNNLP-SNWPTGGAVNIEDYSCRYRDEL--DLVLKQ 1284

  Fly  1079 LSFVIKPKEKVGIVGRTGAGKSSLINALFRL-SYNDGSVRIDDKDTNDMGLHDLRSKISIIPQEP 1142
            :|..|.|.:|||:.||||||||||..||||: ...||::.||...|:.:||||||.|::|||||.
 Worm  1285 ISLNILPGQKVGVCGRTGAGKSSLALALFRIVEAADGNISIDQTITSHIGLHDLREKLTIIPQEN 1349

  Fly  1143 VLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVCLAR 1207
            |||:.|:|.|:||..:::|.:||.|||...||..|..:...||:.:.|||.|||||||||:||.|
 Worm  1350 VLFANTLRFNIDPKGQFTDQQLWLALENSNLKAHVELLPHKLESPVAEGGENFSVGQRQLLCLTR 1414

  Fly  1208 AILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGRVVE 1272
            |:||.:::||:|||||.:|.:||.::|||||.||.:.|::|:|||||||:|.||::||||||:||
 Worm  1415 ALLRKSKVLVLDEATAGIDNRTDTMVQATIREKFADSTIITIAHRLHTIIDYDRIIVMDAGRIVE 1479

  Fly  1273 FGTPYELLTADDTNAFQDLVK 1293
            .|.|.||| .:..:.|..|.|
 Worm  1480 DGIPGELL-KNRNSQFYGLAK 1499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	435/1386 (31%)
mrp-3	NP_001359552.1	MRP_assoc_pro	25..1501	CDD:188098	435/1386 (31%)