Protein Alignment CG31792 and haf-3

DIOPT Version :9

• Sequence 1: NP_001260548.1
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_506927.2
• Gene: haf-3 / 180056
• WormBaseID: WBGene00001813
• Length: 666
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 144/557 - (25%)
• Similarity: 239/557 - (42%)
• Gaps: 94/557 - (16%)

  Fly   779 AAYIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKD 843
            ||.||.:.|...:::.                .|..|:|..:.|..|.||:||..|.|::|.|.|
 Worm   155 AARIYCMHTAGQLVIN----------------DLRKSVFNSVLRQDMAFFDKNKVGEIVSRLSTD 203

  Fly   844 ---------MGQVDEMLPTIIMTVIQDFLLFG-GNIIV---IAIVNPLFLIPALAFGIVIYYLRS 895
                     |...|.....|        ..|| |.::|   :|:...:|::..:..|....: ..
 Worm   204 ALIVGYSVSMNLSDGARALI--------TCFGSGGLMVYTSLAMCKVIFVVVPVIVGTFAVF-GK 259

  Fly   896 FYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTS 960
            ...|.:|.::...|......    ...|:.:.|:|...|.   ..|...|.|..:  ....||..
 Worm   260 LQRKYTLMMQEAVAGANQVA----TERLSSVRTVRMLVAE---RKELAAYSDKIN--EIWQISKK 315

  Fly   961 RAFAYWMDIFCVLFIAMITLSFFIFPPSSAADVGL------------AITQAMGLTGTVQWTVRQ 1013
            ...|.........|...:.||..:|..|:....||            |:..|..|:....:.:
 Worm   316 EGLAKGFMFGSFQFTGYLALSSILFYGSNLISQGLLTYGELSSFCLYAVLSAGSLSAMSGFYL-- 378

  Fly  1014 SAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYE----PYLKSES 1074
              ||...:.:..|:.|.:..||..|||...            :|..|:.::|:|    .|...:.
 Worm   379 --ELMKGLGASSRLFELKNREPRIPLEGGV------------QIGNVKDTIRFEHVAFGYADRDP 429

  Fly  1075 VLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYN--DGSVRIDDKDTNDMGLHDLRSKISI 1137
            :..::||.:...:...:||.:|:|||::.:.|.|| |:  .|.:.:|..|..|:.....|..|..
 Worm   430 LFHNISFDVPAGKITAVVGSSGSGKSTIASLLLRL-YDPTSGRILVDGTDLKDIDPSYWRRHIGT 493

  Fly  1138 IPQEPVLFSGTVRHN-----LDPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFSV 1197
            :.|||||||.|::.|     |:| :..:|..:..|.::....:.::......:||:.|.||..|.
 Worm   494 VGQEPVLFSTTIKENIIYGSLEP-ENVTDAEIVSAADQSNADEFISRFPIKYDTKVGEHGSTLSG 557

  Fly  1198 GQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKF---RECTVLTVAHRLHTIMDS 1259
            ||:|.:.:|||::....||:|||||:.:|..::.|::..: ||.   .:.||:.:||||.||..:
 Worm   558 GQKQRIAIARALVNKPNILIMDEATSALDASSEYLVRIAL-NKLLANSKQTVMIIAHRLSTIKHA 621

  Fly  1260 DRVLVMDAGRVVEFGTPYELLTADDTNAFQDLV-KQT 1295
            |:::|:|.|.|.|.|:..||:...| ..|:.|| |||
 Worm   622 DQIVVVDRGSVAESGSYDELIAIPD-GIFRKLVEKQT 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_001260548.1	CFTR_protein	12..1281	CDD:273530	137/540 (25%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	434..634	CDD:213217
		ABC_membrane	736..980	CDD:294371	43/213 (20%)
		ABCC_MRP_domain2	1055..1276	CDD:213211	74/234 (32%)
haf-3	NP_506927.2	MdlB	70..657	CDD:224055	142/555 (26%)
		ABC_membrane	96..366	CDD:279056	50/244 (20%)
		P-loop_NTPase	415..656	CDD:304359	78/244 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000