Protein Alignment CG31792 and Abcc3

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_542148.2
• Gene: Abcc3 / 140668
• RGDID: 71101
• Length: 1523
• Species: Rattus norvegicus
• Alignment Length: 1394
• Identity: 485/1394 - (34%)
• Similarity: 749/1394 - (53%)
• Gaps: 166/1394 - (11%)

  Fly     4 FKNEDLPEN--PRERSNIFSALSFWYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSW- 65
            |..|:|..|  |...:..||.||||:.....|.|.:..|...||:...:|..:..:..:|..:|
  Rat   197 FSPENLDTNPCPEASAGFFSRLSFWWFTKLAILGYRRPLEDSDLWSLSEEDCSHKVVQRLLEAWQ 261

  Fly    66 ------------------ANELET------NKKNASLLRVLFRVFGRYFVFLGLVLFCLEVILTV 106
                              |.|.|.      ..|..|.||.|.|.|....:.........:::..:
  Rat   262 KQQTQASGPQTAALEPKIAGEDEVLLKARPKTKKPSFLRALVRTFTSSLLMGACFKLIQDLLSFI 326

  Fly   107 QPMFLMKLISSFSNP-SPTSNGVAYAYAGGVILGSALKVILMNPYSFAVTHLGLKIRVGVSSMIY 170
            .|..|..||...|:| :||..|  :..||.:.:.|.::.::::.:...:..:.|:||..:..:||
  Rat   327 NPQLLSILIRFISDPTAPTWWG--FLLAGLMFVSSTMQTLILHQHYHCIFVMALRIRTAIIGVIY 389

  Fly   171 RKCLRLTKTDLGEISTGHIINLISNDLGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFG 235
            ||.|.:|.:...|.:.|.::||:|.|..|......|.:.||.||||.::..|.::|.:|.:|:.|
  Rat   390 RKALTITNSVKREYTVGEMVNLMSVDAQRFMDVSPFINLLWSAPLQVILAIYFLWQILGPSALAG 454

  Fly   236 MTFILLFIPLQMYLGKKISGLRLKTAIRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHK 300
            :..|:|.|||...:..|:...:::.....|.|:::|:||:.||:|:|:||||..|.:.|...|..
  Rat   455 VAVIVLLIPLNGAVSMKMKTYQVQQMKFKDSRIKLMSEILNGIKVLKLYAWEPTFLEQVEGIRQS 519

  Fly   301 EINSIRHVAYAKCL---IWSFNRFLTPVSIFLSLVG-FVLMGR--FLTAEVAFLITAYYNVVR-- 357
            |:..:|..||.:.:   ||    ..||..:.|..:| :|.:.:  .|.||.||:..:.:|:::
  Rat   520 ELQLLRKGAYLQAISTFIW----VCTPFMVTLITLGVYVCVDKNNVLDAEKAFVSLSLFNILKIP 580

  Fly   358 TNMTAYFSVGVTQTAETLVSIKRVQKLLLSGEVVAKDENVVSNGAEEDLQEAREKLLVTPTPMRA 422
            .|:......|:|||:   ||:||:|..|              |..|.|.|....|   |.:|.||
  Rat   581 LNLLPQLISGMTQTS---VSLKRIQDFL--------------NQDELDPQCVERK---TISPGRA 625

  Fly   423 PEKPPHNSEDCVSISELKAKWTTNSPDYTLSGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELR 487
                       ::|......|:.:.|. ||..:|:|:..|||||:||..|.|||||:.|:|||:.
  Rat   626 -----------ITIHNGTFSWSKDLPP-TLHSLNIQIPKGALVAVVGPVGCGKSSLVSALLGEME 678

  Fly   488 VESGEIEVTGSMSYASQEPWLFSGTVRQNILFGQPMDRRRYDLVVRKCALERDFELLPLKDKTIL 552
            ...|.:.|.||::|..|:.|:.:.|:::|:||||||:.:||...:..|||..|.::||..|:|.:
  Rat   679 KLEGAVSVKGSVAYVPQQAWIQNCTLQENVLFGQPMNPKRYQQALETCALLADLDVLPGGDQTEI 743

  Fly   553 GDRGASLSGGQKARISLARSVYRDASIYLLDDPLSAVDSSVARRLFEECL--RGHLRDKIVILVT 615
            |::|.:|||||:.|:||||:||.||:|:|||||||||||.||:.:|::.:  .|.|..|..:|||
  Rat   744 GEKGINLSGGQRQRVSLARAVYSDANIFLLDDPLSAVDSHVAKHIFDQVIGPEGVLAGKTRVLVT 808

  Fly   616 HQLQFLQQADQIVIMEMGKVKAVGTYESLHKSGLDFG--------------------------IV 654
            |.:.||.|.|.|:::..|::..:|.|..|.:....|.                          ::
  Rat   809 HGISFLPQTDFIIVLADGQITEMGHYSELLQHDGSFANFLRNYAPDENQEANEGVLQHANEEVLL 873

  Fly   655 LDDPVN------DNEAA--EDRSR----TSSITDQRRSSVKSVLS-HAESCPEDVGEEQKIN--- 703
            |:|.::      |.|.|  |.|.:    .||::.:.....:.||. :..|..::|...|...
  Rat   874 LEDTLSTHTDLTDTEPAIYEVRKQFMREMSSLSSEGEGQNRPVLKRYTSSLEKEVPATQTKETGA 938

  Fly   704 LQRQQLGRNG---LGVYVDYFRAGGGFLSFSVVMTFFVC----SQGLASLG-DYFLSPWVSRNEK 760
            |.::::...|   |.||.||.::.|      :..|.|:|    .|...::| :.:||.|.:..|:
  Rat   939 LIKEEIAETGNVKLSVYWDYAKSVG------LCTTLFICLLYAGQNAVAIGANVWLSAWTNDVEE 997

  Fly   761 MVAHNYTTDAKDADFEMHAAYIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRGISRASM 825
            ....|.|:....         :|..:.:|..::.:..:|.....|::|:..||.::.....||..
  Rat   998 HGQQNNTSVRLG---------VYATLGILQGLLVMLSAFTMVVGAIQAARLLHTALLHNQIRAPQ 1053

  Fly   826 YFFNKNPAGSILNRFSKDMGQVDEML-PTIIMTVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIV 889
            .||:..|:|.||||||||:..:||:| |||:| :...|......|:||....|||.:..|...:.
  Rat  1054 SFFDTTPSGRILNRFSKDIYVIDEVLAPTILM-LFNSFYTSISTIVVIVASTPLFCVVVLPLAVF 1117

  Fly   890 IYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGSILEAEFDGYQDMHSSASY 954
            ..:::.||:.||..:||||:.:|||::|||:.::.|.|.|||:|.....:...|...|.:...:|
  Rat  1118 YGFVQRFYVATSRQLKRLESVSRSPIFSHFSETVTGTSVIRAYGRVQDFKVLSDAKVDSNQKTTY 1182

  Fly   955 MFISTSRAFAYWMDIF------C-VLFIAMITLSFFIFPPSSAAD--VGLAITQAMGLTGTVQWT 1010
            .:|:::|    |:.:.      | |||.|:    |.:...:|...  |||:::.|:.:|.::.|.
  Rat  1183 PYIASNR----WLGVHVEFVGNCVVLFSAL----FAVIGRNSLNPGLVGLSVSYALQVTLSLNWM 1239

  Fly  1011 VRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHESWPEQGKIEFVELSLRYEPYLKSESV 1075
            :|..::||:.:|:|||:.||.:.|.|.|....:::.| |.||..|.:||...|:||.|.|  |.|
  Rat  1240 IRTLSDLESNIIAVERVKEYSKTETEAPWVLESNRAP-EGWPRSGVVEFRNYSVRYRPGL--ELV 1301

  Fly  1076 LKSLSFVIKPKEKVGIVGRTGAGKSSLINALFR-LSYNDGSVRIDDKDTNDMGLHDLRSKISIIP 1139
            ||:|:..::..|||||||||||||||:...||| |...:|.:.||..:...:|||||||:::|||
  Rat  1302 LKNLTLHVQGGEKVGIVGRTGAGKSSMTLCLFRILEAAEGEIFIDGLNVAHIGLHDLRSQLTIIP 1366

  Fly  1140 QEPVLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVASVATGLETKITEGGSNFSVGQRQLVC 1204
            |:|:|||||:|.|||||..|||:.:|..||...|...|:|..|||:.:.:|||.|.|||||||||
  Rat  1367 QDPILFSGTLRMNLDPFGRYSDEDIWRTLELSHLSAFVSSQPTGLDFQCSEGGDNLSVGQRQLVC 1431

  Fly  1205 LARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTVLTVAHRLHTIMDSDRVLVMDAGR 1269
            ||||:||.:|:||:|||||.:|.:||.|||.|||.:|.:|||||:||||:||||.:||||:|.|.
  Rat  1432 LARALLRKSRVLVLDEATAAIDLETDDLIQGTIRTQFEDCTVLTIAHRLNTIMDYNRVLVLDKGV 1496

  Fly  1270 VVEFGTPYELLTADDTNAFQDLVKQTGQA 1298
            |.||.:|..|:.|.  ..|..:.|..|.|
  Rat  1497 VAEFDSPVNLIAAG--GIFYGMAKDAGLA 1523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	484/1391 (35%)
Abcc3	NP_542148.2	MRP_assoc_pro	7..1522	CDD:188098	483/1391 (35%)