Protein Alignment CG31792 and Abcc2

DIOPT Version :10

• Sequence 1: NP_724148.2
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_038834.2
• Gene: Abcc2 / 12780
• MGIID: 1352447
• Length: 1543
• Species: Mus musculus
• Alignment Length: 1417
• Identity: 471/1417 - (33%)
• Similarity: 747/1417 - (52%)
• Gaps: 192/1417 - (13%)

  Fly     5 KNEDLPENPRERSNIFSALSF-WYTIPTFIKGQKVTLGAKDLYRALKEHRAESLGNKLCSSWANE 68
            ::.|....|...::..|:::| ||. .|.:||.|..|..:|::...:..:|:||.:|..:....:
Mouse   185 ESSDSTHAPSATASFLSSVTFSWYD-STVLKGYKHPLTIEDVWDIEENLKAKSLTSKFKTIMTKD 248

  Fly    69 LE------------------------TNKKNAS--------------------------LLRVLF 83
            |:                        |.|::.|                          |::.||
Mouse   249 LQKARQALQRRLKKSQQSPEGTSHGLTKKQSQSQDVLVLEDSKKKKKKSEATKDFPKSWLVKALF 313

  Fly    84 RVFGRYFVFLGLVLFCL--EVILTVQPMFLMKLISSFSNPSPTSNGVAYAYAGGVILGSALKVIL 146
            :.|  |.|.|...:..|  :::|.:.|..|..||....:|. :...|.|.||           ||
Mouse   314 KTF--YVVILKSFILKLAHDILLFLNPQLLKFLIGFVKDPD-SYPWVGYIYA-----------IL 364

  Fly   147 MNPYSFAVT---------------HLGLKIRVGVSSMIYRKCLRLTKTDLGEISTGHIINLISND 196
            |    |:||               .||:.:|..:.:.:|:|.|.|:.....:.:.|..:||:|.|
Mouse   365 M----FSVTLIQSFFLQCYFQFCFVLGMTVRTTIIASVYKKALTLSNLARRQYTIGETVNLMSVD 425

  Fly   197 LGRMDTFIQFTHYLWLAPLQALMVTYLMYQEIGIAAVFGMTFILLFIPLQMYLGKKISGLRLKTA 261
            ..::.....:.|.||.:.||..:..:.:::|:|.:.:.|:..::|.:|:...|..||..::::..
Mouse   426 SQKLMDVTNYIHLLWSSVLQIALSIFFLWRELGPSILAGVGLMVLLVPVNGVLATKIRKIQVQNM 490

  Fly   262 IRSDKRMRIMTEIIAGIQVIKMYAWELPFEKMVAHARHKEINSIRHVAYAKCLIWSFNRFLTP-- 324
            ...|||::||.||::||:::|.:|||..|::.|...|.||:.::...:..:.:: .|...|||
Mouse   491 KNKDKRLKIMNEILSGIKILKYFAWEPSFKEQVNSIRKKELRNLLRFSQLQTIL-IFILHLTPTL 554

  Fly   325 VSIFLSLVGFVLMG--RFLTAEVAFLITAYYNVVRTNMTAYFSVGVTQTAETLVSIKRVQKLLLS 387
            ||:....| :||:.  ..|.||.||.....:|::|..: |...:.::...:..||:.|:::.|.|
Mouse   555 VSVITFSV-YVLVDSQNVLNAEKAFTSITLFNILRFPL-AMLPMVISSVIQASVSVDRLEQYLGS 617

  Fly   388 GEVVAKDENVVSNGAEEDLQEAREKLLVTPTPMRAPEKPPHNSEDCVSISELKAKWTTNSPDYTL 452
            .::              ||...|...               :.:..|..||....|..:. :.|:
Mouse   618 DDL--------------DLSAIRHVC---------------HFDKAVQFSEASFTWDRDL-EATI 652

  Fly   453 SGVNLQVHAGALVAIVGHTGSGKSSLIQAILGELRVESGEIEVTGSMSYASQEPWLFSGTVRQNI 517
            ..|||.:..|.|||:||..||||||||.|:|||:....|.|.:.||::|..|:.|:.:||::.||
Mouse   653 QDVNLDIKPGQLVAVVGTVGSGKSSLISAMLGEMENVHGHITIKGSIAYVPQQAWIQNGTIKDNI 717

  Fly   518 LFGQPMDRRRYDLVVRKCALERDFELLPLKDKTILGDRGASLSGGQKARISLARSVYRDASIYLL 582
            |||...|.::|..|:..|||..|.|:||..|...:|::|.:||||||.|:||||:.|:||.||:|
Mouse   718 LFGSEYDEKKYQRVIEACALLPDLEMLPGGDMAEIGEKGINLSGGQKHRVSLARATYQDADIYIL 782

  Fly   583 DDPLSAVDSSVARRLFEECL--RGHLRDKIVILVTHQLQFLQQADQIVIMEMGKVKAVGTYESL- 644
            ||||||||:.|.:.:|.:.:  .|.|..|..|||||.:.||.|.|:||::..|.:...|:|..|
Mouse   783 DDPLSAVDTHVGKHIFNKVVGPNGLLSGKTRILVTHGIHFLPQVDEIVVLGKGTILEKGSYSDLM 847

  Fly   645 HKSGL-----------------------------DFGI------VLDDPVN-----DNEAAEDRS 669
            .|.|:                             |.|:      :.||..:     :|......|
Mouse   848 DKKGVFAKNWKTFMKHSGPEGEATVDNDSEEEDGDCGLIPTVEEIPDDAASLTMRRENSLRRTLS 912

  Fly   670 RTSSITDQRRSSVKSVLS----HAESCPEDVGEEQK-INLQRQQLGRNGLGVYVDYFRAGGGFLS 729
            |:|....:|..|:||.|.    :|.:..|:|.:.|| |..:..:.|:....:|:.|.:| .|:.|
Mouse   913 RSSRSGSRRGKSLKSSLKIKSVNALNKKEEVVKGQKLIKKEFVETGKVKFSIYLKYLQA-VGWWS 976

  Fly   730 FSVVMTFFVCSQGLASLG-DYFLSPWVSRNEKMVAHNYTTDAKDADFEMHAAY-IYMLITVLSIM 792
            ...::.|:|.:. :|.:| :.:||.|.|.:||....:.:...:|....:..|. |...|.:||
Mouse   977 LLFIVIFYVLNY-VAFIGTNLWLSAWTSDSEKQNGTDNSPSQRDMRIGVFGALGIAQGIFLLS-- 1038

  Fly   793 VTIKRSFLFFNLAMR-ASIQLHNSMFRGISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIM 856
                 |.|:...|.| ||..||..:...|.||.|.||:..|.|.|:|||:.|:..||:.||..:.
Mouse  1039 -----SSLWSIYACRNASKTLHRQLLTNILRAPMSFFDTTPTGRIVNRFAGDISTVDDTLPQTLR 1098

  Fly   857 TVIQDFLLFGGNIIVIAIVNPLFLIPALAFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAA 921
            :.:..|......:::|.:..|:|:|..:...|:...::.||:.||..::||::.|:||:||||:.
Mouse  1099 SWLLCFFGIVSTLVMICMATPIFIIIIIPLSILYVSVQVFYVATSRQLRRLDSVTKSPIYSHFSE 1163

  Fly   922 SLNGLSTIRAFGAGSILEAEFDGYQDMHSSASYMFISTSRAFAYWMDIFCVLFIAMITLSFFIFP 986
            :::||..||||.......|..:...|.:....:.:|:::|..|..:::...|.:....|...|:.
Mouse  1164 TVSGLPVIRAFEHQQRFLANSEKQIDTNQKCVFSWITSNRWLAIRLELVGNLIVFCSALLLVIYK 1228

  Fly   987 PSSAAD-VGLAITQAMGLTGTVQWTVRQSAELENTMISVERMIEYEEIEPEGPLEATADKKPHES 1050
            .|...| ||..::.|:.:|.|:.|.||.::|:|..:::|||:.||..::.|.|.  ..||||...
Mouse  1229 NSLTGDTVGFVLSNALNITQTLNWLVRMTSEVETNIVAVERINEYINVDNEAPW--VTDKKPPAD 1291

  Fly  1051 WPEQGKIEFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFR-LSYNDG 1114
            ||::|:|:|....:||.|.|  :.|||.::..||..||||:|||||||||||.|.||| |....|
Mouse  1292 WPKKGEIQFNNYQVRYRPEL--DLVLKGITCNIKSTEKVGVVGRTGAGKSSLTNCLFRILESAGG 1354

  Fly  1115 SVRIDDKDTNDMGLHDLRSKISIIPQEPVLFSGTVRHNLDPFDEYSDDRLWCALEEVELKDVVAS 1179
            .:.||..|...:||||||.:::||||:|:||||.:|.|||||::|||:.:|.|||...||..||.
Mouse  1355 QIIIDGIDIASIGLHDLRGRLTIIPQDPILFSGNLRMNLDPFNKYSDEEIWRALELAHLKSFVAG 1419

  Fly  1180 VATGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFREC 1244
            :..||..::||||.|.|:|||||:||.||:||.::|||:|||||.||.:||:|||.||||:|.:|
Mouse  1420 LQLGLLHEVTEGGDNLSIGQRQLLCLGRAVLRKSKILVLDEATAAVDLETDSLIQTTIRNEFSQC 1484

  Fly  1245 TVLTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTG 1296
            ||:|:|||||||||||:::|:|:|::||:|:|.|||:  :...|..:.|:.|
Mouse  1485 TVITIAHRLHTIMDSDKIMVLDSGKIVEYGSPEELLS--NMGPFYLMAKEAG 1534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_724148.2	PLN03130	7..1313	CDD:215595	471/1415 (33%)
Abcc2	NP_038834.2	MRP_assoc_pro	10..1535	CDD:188098	471/1417 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	260..285		3/24 (13%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	903..927		6/23 (26%)