Protein Alignment CG31792 and abcb8

DIOPT Version :9

• Sequence 1: NP_001260548.1
• Gene: CG31792 / 35163
• FlyBaseID: FBgn0051792
• Length: 1323
• Species: Drosophila melanogaster
• Sequence 2: NP_001121515.1
• Gene: abcb8 / 100158634
• XenbaseID: XB-GENE-1010256
• Length: 688
• Species: Xenopus tropicalis
• Alignment Length: 575
• Identity: 141/575 - (24%)
• Similarity: 252/575 - (43%)
• Gaps: 64/575 - (11%)

  Fly   755 VSRNEKMVAHNYTTDAKDADFEMHAAYIYMLITVLSIMVTIKRSFLFFNLAMRASIQLHNSMFRG 819
            |||..:..|.||..:.:....::...|....:.....:|.:.|      :..|.:..:..|:|..
 Frog   148 VSRYTREHAGNYLQEVQGPALKLLCLYGAQGLLTCGYIVLLSR------VGERVAGSMRKSLFFS 206

  Fly   820 ISRASMYFFNKNPAGSILNRFSKDMGQVDEMLPTIIMTVIQDFLLFGGNIIVIAIVNP------L 878
            :.|..:.||:....|.::||.:.|:.:.......:|...::......|..:.:..::|      |
 Frog   207 LLRQDVAFFDAEKTGLLVNRLTSDVQEFKSSFKQVISQGLRSLTQTVGCFLSLYYISPKLTGLLL 271

  Fly   879 FLIPAL--AFGIVIYYLRSFYLKTSLDVKRLEASTRSPVYSHFAASLNGLSTIRAFGAGS----I 937
            .::|.|  :..::..:||....:....|.|.......        :|..:.|::||...|    :
 Frog   272 VVMPVLVGSGALIGSFLRKLSRRAQEQVARATGLADE--------ALGNVRTVKAFAMESREMEL 328

  Fly   938 LEAEFD---GYQDMHSSASYMFISTSRAFAYWMDIFCVLFIAMITLSFFIFPPSSAADVGLAITQ 999
            ..||.|   |..::......:|...|.           :.:..|.|.......|..:...|:..:
 Frog   329 YSAEVDKSSGQNEVLGVGIAVFQGLSN-----------VVLNCIVLGTIFAGGSLMSSKELSAGE 382

  Fly  1000 AMGL---TGTVQWTVRQSAELENTMI----SVERMIEYEEIEPEGPLEATADKKPHESWPEQGKI 1057
            .|..   :.|||.::...:.|...::    :..|:.|:..:||..||.. ..|.|    ..:|:|
 Frog   383 LMSFLVASQTVQRSMANMSVLFGQVVRGLSAGGRVFEFMSLEPTIPLSG-GFKLP----VLRGEI 442

  Fly  1058 EFVELSLRYEPYLKSESVLKSLSFVIKPKEKVGIVGRTGAGKSSLINALFRLSYN--DGSVRIDD 1120
            .|.::|..| |......||:|....|...:.|.:||::|.|||: :.||....|:  :|:|::|.
 Frog   443 HFKDVSFSY-PTRPGHEVLRSFDLRIPHGKTVALVGQSGGGKST-VAALLERFYDPTEGAVQLDG 505

  Fly  1121 KDTNDMGLHDLRSK-ISIIPQEPVLFSGTVRHNL---DPFDEYSDDRLWCALEEVELKDVVASVA 1181
            .|...:....||.: |..|.||||||..|:..|:   .|  :.:|..:..|..:......:.|..
 Frog   506 VDIRILDPSWLRGEVIGFINQEPVLFGTTIIENIRFGRP--DATDAEVHEAAIQANADSFIRSFP 568

  Fly  1182 TGLETKITEGGSNFSVGQRQLVCLARAILRDNRILVMDEATANVDPQTDALIQATIRNKFRECTV 1246
            .|..|.:.|.|...|.||:|.|.:|||:|:|.:||::||||:.:|.:::..:|..:.......||
 Frog   569 EGYNTMLGERGVTLSGGQKQRVAIARALLKDPKILILDEATSALDTESERAVQVALDRARSGRTV 633

  Fly  1247 LTVAHRLHTIMDSDRVLVMDAGRVVEFGTPYELLTADDTNAFQDLVKQTGQATYD 1301
            |.:||||.||.::|.::|:..|:|.||||..:||...  ..:.||:::..|.:.:
 Frog   634 LVIAHRLSTISEADFIVVLSKGQVAEFGTHQDLLRRG--GLYADLIRRQNQESQE 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31792	NP_001260548.1	CFTR_protein	12..1281	CDD:273530	137/553 (25%)
		ABC_membrane	94..360	CDD:294371
		ABCC_MRP_domain1	434..634	CDD:213217
		ABC_membrane	736..980	CDD:294371	41/239 (17%)
		ABCC_MRP_domain2	1055..1276	CDD:213211	78/226 (35%)
abcb8	NP_001121515.1	ABC_6TM_ABCB8_like	123..417	CDD:350018	49/293 (17%)
		MsbA_rel	187..680	CDD:131259	132/528 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000