DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10650 and CG4377

DIOPT Version :9

Sequence 1:	NP_001286081.1	Gene:	CG10650 / 35162	FlyBaseID:	FBgn0046302	Length:	425	Species:	Drosophila melanogaster
Sequence 2:	NP_611614.1	Gene:	CG4377 / 37489	FlyBaseID:	FBgn0034664	Length:	231	Species:	Drosophila melanogaster

Alignment Length:	190	Identity:	57/190 - (30%)
Similarity:	76/190 - (40%)	Gaps:	42/190 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 CQQCLGEANCATTNVTDTQYNAV--CPNNGQVCVNQLNDNKTVTRQC-------GDPCAAGTEST 150
            |..|.| .||:.|    |:.||.  |.:...|||....|.....|.|       |....|..:..
  Fly    37 CYSCEG-INCSRT----TRQNATVSCSDRLDVCVTIYEDFAVSERGCFSQISLAGQAKCAAKDDQ 96

  Fly   151 CSSCSASLC-NVGLFPANRR--QCYNCSGE---NCN--AVSNTLVAGC---SQIDAGCF--TTGT 202
            |..||..|| |||     ||  :|..|.|.   :||  |.::.....|   :..::.|:  ..|.
  Fly    97 CQKCSGQLCNNVG-----RRDFKCIQCIGSDSADCNKGATASLAATQCALPTSANSYCYVKVVGD 156

  Fly   203 SASNMTRGCTSATTEIK-CASDSTDPSCLVCNSD---FCNSPTYEREAGSCIICENCAEQ 258
            ...::.|||..:..|.| |..||....||..||.   .||:  |:.|.|.    ::.|||
  Fly   157 QKDSLQRGCALSVKEQKACLEDSKCSLCLPENSSDSVACNN--YDLELGP----KSSAEQ 210

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10650	NP_001286081.1	DUF753	94..234	CDD:283175	47/161 (29%)
		DUF753	170..309	CDD:283175	29/103 (28%)
		DUF753	277..370	CDD:283175
CG4377	NP_611614.1	DUF753	36..184	CDD:283175	45/156 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR21721
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100