DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Swip-1 and efhd1

DIOPT Version :9

Sequence 1:	NP_001286079.1	Gene:	Swip-1 / 35158	FlyBaseID:	FBgn0032731	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_001292523.1	Gene:	efhd1 / 335521	ZFINID:	ZDB-GENE-030131-7461	Length:	227	Species:	Danio rerio

Alignment Length:	217	Identity:	115/217 - (52%)
Similarity:	147/217 - (67%)	Gaps:	6/217 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSVSSNASSASNKDSVDSPSSTTNTD-SSELTHILNRRQEIMESQEAGIEVRRTYKVVNVYTDFP 64
            :...:|..:...:..| .|::|.:.| :||||..||||.:|.:    |....:..||.|.||:|.
Zfish    14 LDADTNPGTQDEETPV-KPATTMSDDTTSELTEKLNRRLDIHD----GTAKPKQMKVFNPYTEFK 73

  Fly    65 EFSRNQIKDYQKTFNTYDTARDGFLDLQELKFMMEKLGAPQTHLGLKQMIAEVDEDNDGKISFRE 129
            ||||.||||.:..|..:|:.:|||:||.|||.|||||||||||||||.||.|||||.|||:|:||
Zfish    74 EFSRKQIKDMETMFKRFDSGKDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDYDGKLSYRE 138

  Fly   130 FLLIFRKAQAGELDSDSGLNQLARLTEVDVEQVGVSGAKNFFEAKIEQQLRTNKFHDEIRAEQEE 194
            ||||||:|.||||..:|||..||||:|:||...||.||::|||||.:.....:||..|:|.||||
Zfish   139 FLLIFRRAAAGELQEESGLMALARLSEIDVSTEGVLGARDFFEAKAQALSVRSKFEAELREEQEE 203

  Fly   195 RRREEEERAQRRQQFQQRAAIF 216
            |:|.|.||.|||..|::..:.|
Zfish   204 RKRLELERKQRRAAFKELQSTF 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Swip-1	NP_001286079.1	EFh	73..131	CDD:238008	39/57 (68%)
efhd1	NP_001292523.1	EF-hand_7	83..140	CDD:290234	38/56 (68%)
		EFh	86..140	CDD:238008	38/53 (72%)
		EF-hand_7	119..182	CDD:290234	42/62 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580522
Domainoid	1	1.000	94	1.000	Domainoid score	I7431
eggNOG	1	0.900	-	-		E1_KOG0041
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3596
OMA	1	1.010	-	-		QHG52325
OrthoDB	1	1.010	-	-		D1511376at2759
OrthoFinder	1	1.000	-	-		FOG0003787
OrthoInspector	1	1.000	-	-		otm25375
orthoMCL	1	0.900	-	-		OOG6_105725
Panther	1	1.100	-	-	LDO	PTHR13025
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10220
SonicParanoid	1	1.000	-	-		X2644
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800