DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Swip-1 and efhd-1

DIOPT Version :9

Sequence 1:	NP_001286079.1	Gene:	Swip-1 / 35158	FlyBaseID:	FBgn0032731	Length:	217	Species:	Drosophila melanogaster
Sequence 2:	NP_496961.2	Gene:	efhd-1 / 175073	WormBaseID:	WBGene00012980	Length:	687	Species:	Caenorhabditis elegans

Alignment Length:	204	Identity:	89/204 - (43%)
Similarity:	131/204 - (64%)	Gaps:	5/204 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KDSVDSPSSTTNTDSSELTHILNRRQEIMESQEAGIEVRRTYKVVNVYTDFPEFSRNQIKDYQKT 77
            :|:....::....|.:||...|:||.:|.|.:...:::.   |.:::|.:|.||||.||:.:...
Worm   488 EDTKPVETAPAPVDEAELNDALDRRNKINEGENVPLKMN---KKISLYAEFSEFSRKQIQYFSGI 549

  Fly    78 FNTYDTARDGFLDLQELKFMMEKLGAPQTHLGLKQMIAEVDEDNDGKISFREFLLIFRKAQAGEL 142
            |..||..:|.::|..|||.||||||..|||:.||::|.:||||.|||||.|||.||||.|.:|||
Worm   550 FKKYDEDQDSYIDFNELKRMMEKLGEAQTHIALKELIKKVDEDQDGKISQREFFLIFRLAASGEL 614

  Fly   143 DSDSGLNQLARLTEVDVEQVGVSGAKNFFEAKIEQQLRTNKFHDEIRAEQEERRREEEERAQRRQ 207
            ........||.  .|||.:.||.||.|||:||||:|.:.::|.:|::.|:||::|:|||:..||:
Worm   615 SCSEVFKTLAE--SVDVSKEGVLGAANFFQAKIEEQTKLSRFEEEMKEEKEEKKRQEEEKRARRE 677

  Fly   208 QFQQRAAIF 216
            :|....:||
Worm   678 KFLASKSIF 686

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Swip-1	NP_001286079.1	EFh	73..131	CDD:238008	31/57 (54%)
efhd-1	NP_496961.2	EFh	545..602	CDD:238008	30/56 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	71	1.000	Domainoid score	I6153
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H32580
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1511376at2759
OrthoFinder	1	1.000	-	-		FOG0003787
OrthoInspector	1	1.000	-	-		oto17773
orthoMCL	1	0.900	-	-		OOG6_105725
Panther	1	1.100	-	-	LDO	PTHR13025
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10220
SonicParanoid	1	1.000	-	-		X2644
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.950