DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10431 and Thap3

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_780361.2	Gene:	Thap3 / 69876	MGIID:	1917126	Length:	218	Species:	Mus musculus

Alignment Length:	120	Identity:	42/120 - (35%)
Similarity:	58/120 - (48%)	Gaps:	21/120 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPAHCAVINCSHKY-VHAGSISFHRFPFKRKDLLQKWKEFTQRSAQWMPSKWSALCSRHFGDEDF 64
            ||..||...|.::| .....::||||||.|.:||::|.....| |.:.|.:.:.:||.||..|.|
Mouse     1 MPKSCAARQCCNRYSSRRKQLTFHRFPFSRPELLREWVLNIGR-ADFKPKQHTVICSEHFRPECF 64

  Fly    65 NCSNNRKTLKKNAVPSI-----------RVSEDDSMSGH-----LEQVSPSNRPT 103
            :...|||.||.||||::           .|......||.     ||::.|   ||
Mouse    65 SAFGNRKNLKHNAVPTVFAFQNPTEVCPEVGAGGDSSGRNMDTTLEELQP---PT 116

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206	32/77 (42%)
		zf-AD	123..192	CDD:214871
		zf-C2H2_6	674..700	CDD:290623
		C2H2 Zn finger	677..697	CDD:275368
		C2H2 Zn finger	705..726	CDD:275368
Thap3	NP_780361.2	THAP	4..82	CDD:283206	32/78 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..120		7/23 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	133..154
		HCFC1-binding motif (HBM). /evidence=ECO:0000250	156..159
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	65	1.000	Domainoid score	I9990
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001174
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910