DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10431 and Thap7

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_081185.1	Gene:	Thap7 / 69009	MGIID:	1916259	Length:	309	Species:	Mus musculus

Alignment Length:	272	Identity:	63/272 - (23%)
Similarity:	82/272 - (30%)	Gaps:	104/272 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPAHCAVINC---SHKYVHAGSISFHRFPFKRKDLLQKWKEFTQR---SAQ--WMP-SKWSALCS 56
            ||.||:...|   ..:......|||||.|.|.......|....||   |.|  |.| |::...||
Mouse     1 MPRHCSAAGCCTRDTRETRNRGISFHRLPKKDNPRRGLWLANCQRLDPSGQGLWDPTSEYIYFCS 65

  Fly    57 RHFGDEDFNC-----SNNRKTLKKNAVPSI-----RVSEDDSMSGH-----LEQVSPSNRPTHKQ 106
            :||.:   ||     .:....||:.|||:|     ::.......||     |..||...|
Mouse    66 KHFEE---NCFELVGISGYHRLKEGAVPTIFESFSKLRRTAKTKGHGYPPGLPDVSRLRR----- 122

  Fly   107 TLSSAAESAATGVKATCRFCGSSAINCSSFDKSFELFGMIQK----CFPTLQILQDDTLPKEICQ 167
                            ||      ..||........|....:    |||..:.....|||
Mouse   123 ----------------CR------KRCSERQGPTTPFSPPPRADIICFPVEEASAPATLP----- 160

  Fly   168 ECCLQLERFSQFIDVVMLAQSELQRKYRRQLKIKQEPLVRVKQEACESLDNLFPDEL-DMGLEQD 231
                                              ..|.||:.    ..|::.|.|.| .:|.:.|
Mouse   161 ----------------------------------ASPAVRLD----PGLNSPFSDLLGPLGAQAD 187

  Fly   232 D-GCD-QEETEQ 241
            : ||. |...||
Mouse   188 EAGCSTQPSPEQ 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206	29/90 (32%)
		zf-AD	123..192	CDD:214871	11/72 (15%)
		zf-C2H2_6	674..700	CDD:290623
		C2H2 Zn finger	677..697	CDD:275368
		C2H2 Zn finger	705..726	CDD:275368
Thap7	NP_081185.1	THAP	4..93	CDD:214951	29/91 (32%)
		PHA03247	<111..221	CDD:223021	29/159 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	176..210		9/24 (38%)
		HCFC1-binding motif (HBM). /evidence=ECO:0000250	229..232
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.870