Protein Alignment CG10431 and Zfp276

DIOPT Version :10

• Sequence 1: NP_609924.2
• Gene: CG10431 / 35157
• FlyBaseID: FBgn0032730
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: XP_006531290.1
• Gene: Zfp276 / 57247
• MGIID: 1888495
• Length: 669
• Species: Mus musculus
• Alignment Length: 736
• Identity: 116/736 - (15%)
• Similarity: 203/736 - (27%)
• Gaps: 290/736 - (39%)

  Fly   109 SSAAESAATGVKATCRFC-----------------GSSAINCSSFDKSF-----ELFGMIQKCFP 151
            :.|..:.|.|   .||.|                 |.::...|..::.|     .|.|
Mouse    69 AGAGRTLAMG---HCRLCHGKFSSRSLRSISDRVPGETSERLSPGERVFIRDFQRLLG------- 123

  Fly   152 TLQILQDDTLPKEICQECCLQLERFSQFIDVVMLAQSELQR-------KYRRQLKIKQEPLVRVK 209
             :.:.||..||:.:|:.|      ::||.....|.::.|||       :.:...|:..:|....:
Mouse   124 -VAVHQDPALPQSVCKNC------YTQFYQCHSLLRTFLQRVNVSPAGQRKPCTKVGVQPTTVAE 181

  Fly   210 QEACESLDNLFPDELDM---------GL-----EQDDGCDQEETEQKFQFCEFPMLNAQDIINNC 260
            :.||.:         |:         ||     |....|....:.|:....|:           |
Mouse   182 EGACVA---------DLIASSPRCLHGLVGWVHEHAVSCGSLPSLQRTLSSEY-----------C 226

  Fly   261 DIMEIINLDDPFINIPDDADVGQSERLQPGRTANEMLQNELLTEEHNYAKEEWQLPPHQYKTEKV 325
            .|::.:          ...|.|....:....:...:..:..|.     .|..|
Mouse   227 GIIQAV----------WGCDQGHDFTMDTASSCRALFLDSALA-----VKWAW------------ 264

  Fly   326 EGTDAAPDAAPPPADPPPLQDNIDPPSAPEPRSCKPIVTNVSQIPNPMICELLPQPAPPTSIKPN 390
             |.|.:|..|         |::...|:....|.|:...|.|.
Mouse   265 -GKDLSPRLA---------QNSESNPTGAASRLCQARETQVG----------------------- 296

  Fly   391 IVVLNDSVVESSAAFRLHNCTLCTAKFITIDSLNQHYAHSHSNSTPMVSVPPMNICL-PSLTMNP 454
                                    ::..|:.|::....|||.:|..    |.:..|. |.|.
Mouse   297 ------------------------SETKTLPSVDVALLHSHGDSVG----PGLGPCTQPHLA--- 330

  Fly   455 PMKMESNRGLVATEQSEYWPLEWHNSPVSKQPRKKIDILDM-QSSFLHHKDLIPTATQLSA---- 514
            |.:.....|......|            :...|.|.:..|: :..||...:.....|..|:
Mouse   331 PSEAPGQLGETQVPSS------------TSDDRVKDEFSDLSEGDFLSEDESDKKQTPQSSDESF 383

  Fly   515 -PAPDPQLVAVTASYAKLANRYRKLQLKCKKLKSPRKVHRKTYVCRMCRKGFSKFKNLHHHRRQK 578
             |.|:.:   |:...::.....|..:.|.:|...|:...:|...|                .|::
Mouse   384 EPYPEKK---VSGKKSEGREAKRPEEPKIRKKPGPKPGWKKKLRC----------------EREE 429

  Fly   579 AHFVKLIPNFSGRCSGCLKFFRSRLGLRQHMRYICQSLSLKNHRRLQSFKCRH------------ 631
            ...:...|     ..||...:|...|:::|::        ::|..::...|.|
Mouse   430 LPTIYKCP-----YQGCTAVYRGADGMKKHIK--------EHHEEVRERPCPHPGCNKVFMIDRY 481

  Fly   632 ----------------------------CQAIAFAHWRLYRRH--------------------EL 648
                                        ..|:|.||..|..:.                    ..
Mouse   482 LQRHVKLIHTGPRCCVKQWSPSSPGADWASAVAAAHTALLLQRSAITSVTSAGRPSSSGSTFSST 546

  Fly   649 NCRPKK----SKTKVQTAMNSKKKVTPTQVF--ECNICKKSFGSLNGLRQHNITH--STERQHKC 705
            .|..::    ||..:.||.:..|...|....  .|.:|.........|:.|...|  .||....|
Mouse   547 RCATREPSHCSKCGLGTACDWDKCSLPHLPLPSRCEVCGFQCRQRASLKYHMTKHKAETELDFAC 611

  Fly   706 GICERVFKRRNGLSQHIKGYH 726
            ..|.|.|::.:.|:.|:...|
Mouse   612 DQCGRRFEKAHNLNVHMSMVH 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_609924.2	THAP	5..81	CDD:461662
		zf-AD	123..192	CDD:214871	18/90 (20%)
		SFP1	<665..727	CDD:227516	16/66 (24%)
		zf-C2H2_6	674..697	CDD:433576	4/24 (17%)
		C2H2 Zn finger	677..697	CDD:275368	4/19 (21%)
		C2H2 Zn finger	705..726	CDD:275368	6/20 (30%)
Zfp276	XP_006531290.1	zf-AD	79..156	CDD:462262	17/90 (19%)
		SFP1	<321..476	CDD:227516	32/201 (16%)
		C2H2 Zn finger	581..601	CDD:275368	4/19 (21%)
		C2H2 Zn finger	611..632	CDD:275368	6/20 (30%)