DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10431 and si:ch211-40k21.9

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_001373405.1	Gene:	si:ch211-40k21.9 / 504079	ZFINID:	ZDB-GENE-131122-64	Length:	292	Species:	Danio rerio

Alignment Length:	403	Identity:	85/403 - (21%)
Similarity:	134/403 - (33%)	Gaps:	165/403 - (40%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CAVINCSHKYVHAGSISFHRFPFKRKDLLQKWKEFTQRSAQWMPSKWSALCSRHFGDEDFNCSNN 69
            |:.::|.::......|||||||...||.||||. ...|...:.||..:.:||:||.|..|..:|:
Zfish     3 CSALSCKNRPSPGTGISFHRFPLDDKDRLQKWL-LNLRRDNFQPSPSARICSQHFEDSCFFTNNH 66

  Fly    70 RK-TLKKNAVPSI------------------RVSED----DSMSGHLEQVSPSNRPTHKQTLSSA 111
            .| .|.|:|||::                  .|||:    |...|.|..|..::  .|.:..::|
Zfish    67 GKLCLSKSAVPTLFYYPISFRSWRKYWSKRMVVSEEEKSGDGSRGTLHAVETTD--DHHKPEATA 129

  Fly   112 AESAATGVKATCRFCGSSAINCSSFDKSFELFGMIQKCFPTLQILQDDTLPKEICQECCLQLERF 176
            |                                    ||.|.|.|              |:.|..
Zfish   130 A------------------------------------CFGTPQTL--------------LKTEPR 144

  Fly   177 SQFIDV-VMLAQSELQRKYRRQLKIKQEPLVRVKQEACESLDNLFPDELDMGLEQDD-GCDQEET 239
            |:|::| |:|.:|           ||:|                         |.|| |.|..:|
Zfish   145 SRFVEVDVILNES-----------IKEE-------------------------EDDDIGLDMPDT 173

  Fly   240 EQKFQFCEFPMLNAQDII------NNCDIMEIINLDDPFINIPDDADVGQSERL----------- 287
            ...      |::...::.      ::|......|.|.  .|...:.:...:|.|
Zfish   174 NVS------PVIYPSEVCVVAVRQDHCYYSSSSNTDG--TNAAGNQESESAEMLRHKLHVVLSKI 230

  Fly   288 ----QPGRTANEM---LQNELLTEEHNYAKEEWQLPPHQYKTEKVEGTDAAPDAAPPPADPPPLQ 345
                :..:..|:|   |::.:|:.:.|...|..|....|....|                   ||
Zfish   231 KVFRKTMKIKNQMIRRLKSRVLSLKANVKTERLQREKMQVTLSK-------------------LQ 276

  Fly   346 DNIDPPSAPEPRS 358
            .::|....|:|:|
Zfish   277 KDLDCRLQPKPKS 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206	31/76 (41%)
		zf-AD	123..192	CDD:214871	13/69 (19%)
		zf-C2H2_6	674..700	CDD:290623
		C2H2 Zn finger	677..697	CDD:275368
		C2H2 Zn finger	705..726	CDD:275368
si:ch211-40k21.9	NP_001373405.1	THAP	2..80	CDD:214951	31/77 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001174
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910