DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10431 and CG1647

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_651636.1	Gene:	CG1647 / 43401	FlyBaseID:	FBgn0039602	Length:	1222	Species:	Drosophila melanogaster

Alignment Length:	364	Identity:	77/364 - (21%)
Similarity:	122/364 - (33%)	Gaps:	121/364 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 CTLCTAKFITIDSLNQHY-----AHSHSNSTPMVSVPPMNICLPSLTMNPPMKMESNRGLVATEQ 469
            |:.|      :|.:|..|     .::.:..|..         |..|....|.::...:.:|..|:
  Fly    72 CSQC------VDKINDFYEFREMCYATNKQTRN---------LLGLKQIEPARLIDLKRIVKEER 121

  Fly   470 ---------------SEYWPLEWHNSPVSKQPRKKIDILDMQSSFLHHKDLIPTATQLSAPAPDP 519
                           .|.||   .|:.|..|.:|:        ||:.||      .|...|:...
  Fly   122 PISGAVGKRGRKRKGEESWP---KNNNVKPQVKKE--------SFVWHK------KQKLQPSQIT 169

  Fly   520 QLVAVTASYAKLANRYRKLQLKCKKLKSPRKVHRKTYVCRMCRKGFSKFKNLHHHRRQKAHFVKL 584
            .||:......|.....:...||    ..|:|..||: :|.:|.:.|.. |.|....:...| |..
  Fly   170 SLVSKREPEIKDEPAEQDTSLK----GPPKKAGRKS-ICSVCGEKFLS-KELADEHKSLVH-VPS 227

  Fly   585 IPNFSGRCSGCLKFFRSRLGLRQHMRYICQSLSLKNHRRLQS-FKCRHCQ---AIAFAHWRLYRR 645
            ||.:.  |:.|.:...::..:|.|..:         |:..:: :||..|:   |.|:|..|..|.
  Fly   228 IPRYI--CNACNQTHHNQSDIRAHQLW---------HKLSKTPYKCPLCESSVANAYAFTRHLRE 281

  Fly   646 HELNCRPKKSKTKVQTAMNSKKKVTPTQVF----ECNICKKSFGSLNGLRQHNITHSTE----RQ 702
            |                    ...||.|:.    ||.:|||:|.:       |..::|.    |:
  Fly   282 H--------------------TPPTPVQLLVLDRECPLCKKTFVT-------NFFYNTHRCAIRK 319

  Fly   703 HKCGICERVFKRRNGLSQHIKGYHLQLKPHECPVCQHRY 741
            .|||.|.|.........:|            .|.|...|
  Fly   320 RKCGGCSRTLNTEAAYMRH------------APTCPKIY 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206
		zf-AD	123..192	CDD:214871
		zf-C2H2_6	674..700	CDD:290623	7/29 (24%)
		C2H2 Zn finger	677..697	CDD:275368	6/19 (32%)
		C2H2 Zn finger	705..726	CDD:275368	5/20 (25%)
CG1647	NP_651636.1	zf-AD	19..99	CDD:285071	6/41 (15%)
		C2H2 Zn finger	203..224	CDD:275368	5/21 (24%)
		C2H2 Zn finger	233..253	CDD:275368	4/28 (14%)
		C2H2 Zn finger	262..282	CDD:275368	7/19 (37%)
		C2H2 Zn finger	297..314	CDD:275368	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100