Protein Alignment CG10431 and LOC3290001

DIOPT Version :10

• Sequence 1: NP_609924.2
• Gene: CG10431 / 35157
• FlyBaseID: FBgn0032730
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: XP_061505468.1
• Gene: LOC3290001 / 3290001
• VectorBaseID: AGAMI1_010160
• Length: 547
• Species: Anopheles gambiae
• Alignment Length: 768
• Identity: 145/768 - (18%)
• Similarity: 237/768 - (30%)
• Gaps: 331/768 - (43%)

  Fly     1 MP-AHCAVINCSHKYVHAG----SISFHRFPFKRKDLLQKWKEFTQRSAQWMPSKWSALCSRHFG 60
            || :.||...|:::.|...    ::.||.|| ..:.|..:|..|.:|...|.|.|..|:||.||.
Mosquito     1 MPNSKCAAAFCNNRRVDVRKRKLALIFHAFP-ADEALRSRWMAFCRRGVDWTPFKTDAVCSAHFR 64

  Fly    61 DEDF--------NCSNNRKTLKKNAVPSIR------VSEDDSM-----SGHLEQVSPSNRPTHKQ 106
            .||:        ..|.|.:.|:.:||||:|      :|:...:     ...||::...|.|
Mosquito    65 HEDYQMAHSPLLKLSKNLRRLRVDAVPSVREGMVVTISKKQKLEELVRQQRLEELYRQNNP---- 125

  Fly   107 TLSSAAESAATGVKATCRFCGSSAINCSSFDKSFELFGMIQKCFPTLQILQDDTLPKEICQECCL 171
                                  ||...:.||.::....:.::       |:|::   .:.::...
Mosquito   126 ----------------------SAEPSTDFDHTYSGVTVAEE-------LRDES---PMLEKIVY 158

  Fly   172 QLERFSQFIDVVMLAQSELQRKYRRQLKIKQEPLVRVKQEACESLDNLFPDELDMGLEQDDGCDQ 236
            :|::|.....:.:.|             |..|.|........|:|::..
Mosquito   159 RLQKFPNLCALCLRA-------------IDDEKLFTPFASYSEALESTI---------------- 194

  Fly   237 EETEQKFQFCEFPMLNAQDIINNCDIMEIINLDDPFINIPDDADVGQSERLQPGRTANEMLQNEL 301
               ||||           |.|..    |:|          |..:......|.|.:...|.|  |:
Mosquito   195 ---EQKF-----------DEITG----EVI----------DSKERTDIHHLLPDKVCAECL--EV 229

  Fly   302 LTEEHNYAKEEWQLPPHQYKTEKVEGTDAAPDAAPPPADPPPLQDNIDPPSAPEPRSC-KPIVTN 365
            |.:.|:|.::                                ||             | |...|.
Mosquito   230 LIQFHHYQRQ--------------------------------LQ-------------CLKRFSTG 249

  Fly   366 VSQIPNPMICELLPQPAPPTSIKPNIVVLNDSVVESSAAFRLHNCTLCTAKFITIDSLNQHYAHS 430
            ::|:                 :|.|    ...:.|..||                  ...:.|:.
Mosquito   250 MAQL-----------------LKGN----RQPLAELYAA------------------QGDYLANV 275

  Fly   431 HSNSTPMVSVPPMNICLPSLTMNPPMKMESNRGLVATEQSEYWPLEWHNSPVSKQPRKKIDILDM 495
            ..|         :|||         ...|.|..|...|           :.|:...|.|     .
Mosquito   276 LKN---------LNIC---------QAAEENITLQRLE-----------AEVATYGRVK-----K 306

  Fly   496 QSSFLHHKDLIPTATQLSAPAPDPQLVAVTASYAKLANRYRK------LQLKCKKLKSPRKVHRK 554
            .::|  .:||         |.||...|         |||..:      .|:.| ...|||.|.::
Mosquito   307 YTTF--EQDL---------PRPDTNAV---------ANRCEETIPASCFQIDC-SATSPRAVEQR 350

  Fly   555 TYVCRMCRKGFSKFKNLHHHRRQKAHFVKLIPNFSGRCSG--------CLKFFRSRLGLRQHMRY 611
                               ||.:.:...    :.:||...        |.::|..:..|::|:
Mosquito   351 -------------------HRSRSSQEA----DGTGRAKKWICPYEEICREWFLDQASLQKHI-- 390

  Fly   612 ICQSLSLKNHRRLQSFKCRHC-QAIAFAHWRLYRRHELNCRPKKSKTKVQT-------AMNSKKK 668
                     |...:.||||.| ..|.|  :.|:::|            |::       .::..||
Mosquito   391 ---------HDDHKVFKCRTCGYRIKF--YDLFKKH------------VESHDIARALLLSHNKK 432

  Fly   669 VTPTQVFECNICKKSFGSLNGLRQHNITHSTERQHKCGICERVFKRRNGLSQH 721
            .|||: .:|..|.|.|.|...||:|...|:....:.||.|..|:...:..:.|
Mosquito   433 DTPTE-GKCETCGKQFQSDEQLRRHREIHAHSGNYVCGRCLGVYASEHKYNNH 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_609924.2	THAP	5..81	CDD:461662	28/87 (32%)
		zf-AD	123..192	CDD:214871	9/68 (13%)
		SFP1	<665..727	CDD:227516	19/57 (33%)
		zf-C2H2_6	674..697	CDD:433576	8/22 (36%)
		C2H2 Zn finger	677..697	CDD:275368	8/19 (42%)
		C2H2 Zn finger	705..726	CDD:275368	5/17 (29%)
LOC3290001	XP_061505468.1	None