DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10431 and Zfp711

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	XP_002730311.1	Gene:	Zfp711 / 302327	RGDID:	1562768	Length:	805	Species:	Rattus norvegicus

Alignment Length:	429	Identity:	79/429 - (18%)
Similarity:	131/429 - (30%)	Gaps:	168/429 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   407 LHNCTLCTAKFITIDSLNQHYAHSHSNSTPMVSVPPMNICLPSLTMNPPMKMESNRGLVATEQSE 471
            ::.|.:||.||.:...|.:|                       :..:|...|.........:.:.
  Rat   426 VYPCHICTKKFKSRGFLKRH-----------------------MKNHPDHLMRKKYQCTDCDFTT 467

  Fly   472 YWPLEWHNSPVSKQPRKKIDILDMQSSFLHHKDLIPTATQLSAPAPDPQLVAVTASYAKLANRYR 536
            ...:.:||...|.:...|:|                                .|..:.:...|||
  Rat   468 NKKVSFHNHLESHKLINKVD--------------------------------KTHEFTEYTRRYR 500

  Fly   537 KLQ-LKCKKL----KSPRKVHRKTYVCRMC-----RKGFSKFKNLHHHRRQKAHFVKLIPNFSGR 591
            :.. |...||    |.| |:|:    |:.|     .:|......|..|.:...|.
  Rat   501 EASPLSSNKLILRDKEP-KMHK----CKYCDYETAEQGLLNRHLLAVHSKSFPHV---------- 550

  Fly   592 CSGCLKFFRSRLGLRQHMR-------YICQ--------SLSLKNHRRLQ-----SFKCRHCQAIA 636
            |..|.|.||....|::|||       |.||        ..:||.|.:.:     .:||.||.. :
  Rat   551 CVECGKGFRHPSELKKHMRTHTGEKPYQCQYCVFRCADQSNLKTHIKSKHGNNLPYKCEHCPQ-S 614

  Fly   637 FA-------HWRLYRRHELNCRP------------------------------------KKSKTK 658
            |.       |..|::.|:.:..|                                    :.|:.|
  Rat   615 FGDERELQRHLDLFQGHKTHQCPHCDHKSTNSSDLKRHIISVHTKDFPHKCEVCDKGFHRPSELK 679

  Fly   659 VQTAMNSKKKV------------------------TPTQVFECNICKKSFGSLNGLRQHNITHST 699
            ..:.::..:|:                        |..|..:|..||:.|...|.|::|..||:.
  Rat   680 KHSDIHKGRKIHQCRHCDFKTSDPFILSGHILSVHTKDQSLKCKRCKRGFRQQNELKKHMKTHTG 744

  Fly   700 ERQHKCGICERVFKRRNGLSQHIKGYHLQLKPHECPVCQ 738
            .:.::|..||......:|..:|:...|.:..||.|..|:
  Rat   745 RKIYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCEFCK 783

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206
		zf-AD	123..192	CDD:214871
		zf-C2H2_6	674..700	CDD:290623	9/25 (36%)
		C2H2 Zn finger	677..697	CDD:275368	7/19 (37%)
		C2H2 Zn finger	705..726	CDD:275368	5/20 (25%)
Zfp711	XP_002730311.1	Zfx_Zfy_act	65..412	CDD:398398
		COG5048	425..803	CDD:227381	79/429 (18%)
		C2H2 Zn finger	429..449	CDD:275368	7/42 (17%)
		C2H2 Zn finger	522..543	CDD:275368	4/20 (20%)
		C2H2 Zn finger	551..571	CDD:275368	9/19 (47%)
		C2H2 Zn finger	579..600	CDD:275368	5/20 (25%)
		C2H2 Zn finger	608..634	CDD:275368	7/26 (27%)
		C2H2 Zn finger	636..657	CDD:275368	1/20 (5%)
		C2H2 Zn finger	665..685	CDD:275368	2/19 (11%)
		C2H2 Zn finger	722..742	CDD:275368	7/19 (37%)
		C2H2 Zn finger	750..771	CDD:275368	5/20 (25%)
		C2H2 Zn finger	779..799	CDD:275368	2/5 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100