DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10431 and si:ch73-138e16.4

DIOPT Version :9

Sequence 1:	NP_001286078.1	Gene:	CG10431 / 35157	FlyBaseID:	FBgn0032730	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	XP_009294107.1	Gene:	si:ch73-138e16.4 / 108179101	ZFINID:	ZDB-GENE-070705-203	Length:	252	Species:	Danio rerio

Alignment Length:	216	Identity:	54/216 - (25%)
Similarity:	84/216 - (38%)	Gaps:	59/216 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   541 KC-------KKLKSPR------KVH--RKTYVCRMCRKGFSKFKNLHHHRR----QKAHFVKLIP 586
            ||       |.|:|.:      ::|  .|.|.|..|.|...:...|..|.|    :|.|
Zfish    53 KCFTCTECGKSLRSKQSLQFHMRIHTGEKPYTCTECGKSVRQSSALKIHMRIHTGEKPH------ 111

  Fly   587 NFSGRCSGCLKFFRSRLGLRQHMRYICQSLSLKNHRRLQSFKCRHCQAIAFAHWRLYRRHELNCR 651
                :|..|.|.|.....|:.|:|.         |.:.:.:.|..| ..:||.....|:|:
Zfish   112 ----KCDQCGKTFLIHSHLQNHLRV---------HTKEKPYSCCEC-GKSFATQSSLRKHQ---- 158

  Fly   652 PKKSKTKVQTAMNSKKKVTPTQVFECNICKKSFGSLNGLRQHNITHSTERQHKCGICERVFKRRN 716
                  |:.|.:  |:.|       |..|.|:|.:...|::|...|:.|:.:||..|::.|:|..
Zfish   159 ------KIHTGV--KEHV-------CLECGKTFITAQALKKHQRIHTEEKPYKCSYCDKSFRRTG 208

  Fly   717 GLSQHIKGYHLQLKPHECPVC 737
            .|..| :..|...||:.|..|
Zfish   209 DLKVH-ERIHTGEKPYTCDQC 228

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10431	NP_001286078.1	THAP	4..81	CDD:283206
		zf-AD	123..192	CDD:214871
		zf-C2H2_6	674..700	CDD:290623	7/25 (28%)
		C2H2 Zn finger	677..697	CDD:275368	6/19 (32%)
		C2H2 Zn finger	705..726	CDD:275368	6/20 (30%)
si:ch73-138e16.4	XP_009294107.1	C2H2 Zn finger	57..77	CDD:275368	3/19 (16%)
		zf-H2C2_2	69..91	CDD:290200	5/21 (24%)
		COG5048	<81..241	CDD:227381	48/188 (26%)
		C2H2 Zn finger	85..105	CDD:275368	6/19 (32%)
		zf-H2C2_2	97..120	CDD:290200	8/32 (25%)
		C2H2 Zn finger	113..133	CDD:275368	7/28 (25%)
		zf-H2C2_2	125..150	CDD:290200	7/34 (21%)
		C2H2 Zn finger	141..161	CDD:275368	7/30 (23%)
		C2H2 Zn finger	169..189	CDD:275368	6/19 (32%)
		zf-H2C2_2	181..206	CDD:290200	8/24 (33%)
		C2H2 Zn finger	197..217	CDD:275368	6/20 (30%)
		zf-H2C2_2	209..234	CDD:290200	7/21 (33%)
		C2H2 Zn finger	225..245	CDD:275368	2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24406
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100