Protein Alignment L2HGDH and CG3270

DIOPT Version :10

• Sequence 1: NP_609923.2
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_610228.1
• Gene: CG3270 / 35575
• FlyBaseID: FBgn0033093
• Length: 440
• Species: Drosophila melanogaster
• Alignment Length: 476
• Identity: 113/476 - (23%)
• Similarity: 172/476 - (36%)
• Gaps: 149/476 - (31%)

  Fly    10 GLRRSLLNVGVAAPNESTATHKRSQHSSSSCGDYDLVVVGGGIVGAASA-----REIVLRHPSLK 69
            |||| :|.:|......|.:...:......|||   ::::|||.:||:||     |.:.|.. .|.
  Fly     3 GLRR-VLRLGALRQLRSLSGKPQGDVLPGSCG---VLIIGGGGMGASSAFWLKSRALQLGR-KLN 62

  Fly    70 VAVLEKECKLAKHQSGHNSG--VIHAGIYYKPGTLKARLCVEGMHLA-YAY---------LDEKK 122
            |.|:|::       :|:.|.  |:..|     |..:.....|.:.:: :.|         |.:..
  Fly    63 VLVVERD-------AGYTSASTVLSVG-----GVRQQFSLAENIEMSLFGYNFVVNGREHLGDVD 115

  Fly   123 IPYKKTGKLIVATDE------KEVKLLKDLEKRGIANNVPDLRM------IEGSEIQEIEPYCQG 175
            :.|:..|.||:|:::      |..||..:|..|........||.      .||.|:.     |.|
  Fly   116 LCYQPNGYLILASEKGAHILAKNSKLQNELGARNELLGPEALRQRFPWLSTEGVELG-----CHG 175

  Fly   176 VMALHSPHTGIVD-WGLVTEH------YGQDFKQCGGDIYLDFNVS------------------K 215
            :     ...|..| |.|:..:      .|.:|.. |..:..::|.|                  |
  Fly   176 I-----DKEGWFDPWALLMGYKKKARALGANFAN-GSVVGFEWNDSGGLSGAVVDAGDVLQRTVK 234

  Fly   216 FTETKEGTDYPVTIHGAKPGQTVRTKNVLTCGGLQSDLLAEKTGCPRDPRIVPFRGEYLLLTKEK 280
            |       |..|...||..||..|...:   |..::...:.....|.:||   .|..|::.|:.|
  Fly   235 F-------DTCVLAAGAYSGQVARLAGI---GDKEAKEASLSVALPVEPR---KRYVYVVSTQGK 286

  Fly   281 QHMVKGNIYPV---PDPRFPFLGVHFTPRMD---GSIWLG--PNAVLALKRE------GY----T 327
            .  ..|...|:   ||      |.:|  |.|   |:...|  ||.....:.|      ||    .
  Fly   287 N--CPGLATPLTVDPD------GTYF--RRDGLCGNFLCGRSPNEDEEPECETLDVDHGYFETDV 341

  Fly   328 WGDINLFELFDALRYPGF--VKMASKYIGF---------GLSEMSKSWFINLQIKALQKYIPDIT 381
            |..:       |.|.|.|  ||:.|.:.||         |:...... :.||.|.|      ..:
  Fly   342 WPTL-------ANRVPAFESVKIQSSWAGFYDHNTFDANGVIGRHPH-YSNLFIAA------GFS 392

  Fly   382 EYDIQRGPAGVRA-QAMDLDG 401
            .:.||:.||..|| ..:.|||
  Fly   393 GHGIQQTPAVGRAISELILDG 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L2HGDH	NP_609923.2	DAO	56..447	CDD:477422	98/430 (23%)
CG3270	NP_610228.1	DadA	54..427	CDD:440429	95/421 (23%)