Protein Alignment L2HGDH and C15B12.8

DIOPT Version :10

• Sequence 1: NP_609923.2
• Gene: L2HGDH / 35156
• FlyBaseID: FBgn0032729
• Length: 455
• Species: Drosophila melanogaster
• Sequence 2: NP_741814.2
• Gene: C15B12.8 / 259861
• WormBaseID: WBGene00015788
• Length: 385
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 96/459 - (20%)
• Similarity: 166/459 - (36%)
• Gaps: 152/459 - (33%)

  Fly    43 YDLVVVGGGIVGAASAREIVLRHPSLKVAVLEKECKLAKHQSGHNSGVIHAGIYYKPGTLKARLC 107
            ||::|||.||.|:.:|..  .:...|:..:||      ::..||::|..|.         |:|:
 Worm     6 YDVIVVGAGIFGSCTAYH--CQRLGLRTLLLE------QYSLGHSNGSSHG---------KSRI- 52

  Fly   108 VEGMHLAYAYLDEKKIPYKKTGKLIVATDEKEVKLLKDLEKRG--IANNVPDLRMIEGSEIQEIE 170
                 :.||:.|.:.:|.  .|...:..:|.|       :|||  :.|.:..|....|:::..|
 Worm    53 -----IRYAHTDPEYVPL--VGDSYLQIEELE-------KKRGEKLWNKLGLLWAATGNQVDSI- 102

  Fly   171 PYCQGVMALHSPHTGIVDWGLVTEHYGQDFK----------QCGGDIYLDFNVSKFTE---TKEG 222
               .|.:..|:....::....:||.|.| ||          ..||.||.:..:..|.|   |..|
 Worm   103 ---SGHLKKHNIDHEVLPGTKITERYPQ-FKFDDKWTALIDPMGGVIYANKWLKAFQEEFITLGG 163

  Fly   223 T---DYPVTIHGAKPGQTVRTKNVLTCGGLQSDLLAEKTGC------PRDPRIVPFRGEYLLLT- 277
            |   :.||..:|......|..|.  :.|..:::.:....||      |.    |.|:.:.:.|.
 Worm   164 TIQDNEPVISYGETDNVIVNVKT--STGEYKTNKIIFTVGCWITKFFPN----VNFQIKPISLAV 222

  Fly   278 -------KEKQHMVKGNIYPVPDPRFPFLGVHFTPRMDGSIWLGPNAVLA--LKREGYTWGDINL 333
                   ::..|::....:||                          |:|  |:::.|      .
 Worm   223 CYWNAKDEKNNHLLDEKHFPV--------------------------VIAKNLEKKEY------F 255

  Fly   334 FELFDALRYPGFVKMA---SKYIGFGLSEMSKS--WFINLQIKALQKYIPDI---TEYDIQR--- 387
            |.|.|. .|||.:|:.   ...:...||..:|:  ..:.:....::.:||.|   :.|.:.:
 Worm   256 FALPDT-DYPGAIKLVLDEGDDLAGDLSHPTKNNQELVTIPGSFIKDHIPVIDGSSPYKVDQCKY 319

  Fly   388 ----------GPAGVRAQAMDLDGNLVDDFVFDRGQGSGALAKRVLHCRNAPSPGATSSLAIAKM 442
                      ||.......:.:.|         .|.|||        .:.||..|.    ::|:|
 Worm   320 TNSPDHHYLIGPVSSENSKILVGG---------CGSGSG--------FKTAPGIGR----SLAEM 363

  Fly   443 IADK 446
            .|.|
 Worm   364 AAGK 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
L2HGDH	NP_609923.2	DAO	56..447	CDD:477422	88/446 (20%)
C15B12.8	NP_741814.2	soxA_mon	6..384	CDD:130444	96/459 (21%)