Protein Alignment Tango6 and Tango6

DIOPT Version :9

• Sequence 1: NP_609922.2
• Gene: Tango6 / 35155
• FlyBaseID: FBgn0032728
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: XP_226428.6
• Gene: Tango6 / 307816
• RGDID: 1559841
• Length: 1084
• Species: Rattus norvegicus
• Alignment Length: 1048
• Identity: 207/1048 - (19%)
• Similarity: 372/1048 - (35%)
• Gaps: 351/1048 - (33%)

  Fly    71 PDSDRT-----ICYIIRLQHVLHSIMRNINFHSDAKEDLISVAHLKLCIQASQELSYYSLRCQLH 130
            |..|||     :..|:||:...|:..|                 |.:|.:...:|:.::....|
  Rat   171 PLRDRTEFGAVVQGIVRLEAAPHATRR-----------------LYICCRVLLDLAQHASLGSL- 217

  Fly   131 EDFYKSPIFCEAQGKIKANFSLMLLSIQFFINLLHIRQYHIANSMELVQRDLLAAIVSLRVQQDS 195
                   |||...|.|.|.    |..:.|....   |:..:.....|.:.:...:..:||
  Rat   218 -------IFCRHFGDIAAG----LCQLGFCPTK---RKPPVPVEEVLTEEERTLSRQALR----- 263

  Fly   196 PLLDKAIAYLWQYESKADFFRNILLF-----------KATTLCPTLAQLLHRQLLG-----KLHL 244
            .:||:.      |:..|  .|.:|:.           |....||..|.|  |:|.|     :|..
  Rat   264 DILDQV------YQPLA--VRELLILQGGSPQSCTDVKTKLRCPAPAWL--RRLCGQLLSERLMR 318

  Fly   245 PQGFASLVEALHQNPNVNSS------------RNAEIVASIVARKGFSQLAQEK----MVLQVLE 293
            |.|..::|..:.:.....::            :..:::|.|:|......|:.|.    :..|:|:
  Rat   319 PNGVQAVVRGILEGAGAGAAGGSDAEATAADWKKCDLIAKILASCPQQSLSPESYYKDICPQILD 383

  Fly   294 YCKFYLQNADKMCAG----------VLSLRRLYDLSDTNQKLIKEIL--FKHWETLCN-PE-DII 344
            .  |:||  ||:.|.          ...||...:|:.  :.|::.:|  .....|... || |::
  Rat   384 L--FHLQ--DKLTARQFQRVATTTFTTMLRERPELAP--KYLLQPMLAPLHRCSTTAEIPESDMV 442

  Fly   345 NGLILMDHQELCNRILLWQHLFCSSTVACLPSNLLV-PYLPLLLQLYDGLPMELPASSQISAIIL 408
            .|.:|:..:||...:   :.:|....||..|..:|: ..||||     |:...|...:|.||..:
  Rat   443 PGTVLVTEEELSRCV---EDVFKVYVVANEPLPVLLDSLLPLL-----GVFFSLYCFTQQSASHI 499

  Fly   409 RCLDNREMKNELPAILQKLFKWEIEKEPPWKCLNPRIIILPSMNTTQIQVKVAHKDHLAD----H 469
            |            ::.|::..|.:                         ||:..|..:|.    .
  Rat   500 R------------SLCQEILLWAL-------------------------VKLERKRAIASLRGFS 527

  Fly   470 DMGRILPGL-----LTSSSHHS--LTCKVFLSLLGFIAKQINDKSSASVDFISSEAE-------- 519
            .:.:.:|.|     ..:::|..  :|.|..||         :|:..|....:|||..
  Rat   528 GLDKAVPALHPQCQFRAATHGGIVITVKEALS---------DDEDEALYQKVSSEQSQMEHLGDL 583

  Fly   520 -----------------LKDFLH------SKYQLKLDLLIALNQMVAHQPLRAQLSQHTKELLHI 561
                             ||:..|      :::..|.....:|.::..||.|..: .|..|.|:..
  Rat   584 LLHCQPCGLAGDFFIFCLKELSHLLEENEAEFTPKPPCSTSLLELEQHQTLLIE-DQERKLLVLQ 647

  Fly   562 LKDLLVHRSREQDTT-----------------------------DQILLLVLNLLQEILEGSENI 597
            |..:|..:..||..|                             .|.|.:.:.|:..:|.|:..:
  Rat   648 LLAVLCEKMSEQIFTHITQVVDFVAATLQRACAGLAHEAESTVGSQTLSMAMGLVAAMLGGAVQL 712

  Fly   598 QLSE--ACKELKEQLHLLGTRSSNPLIQQ-SVKSLLTI-IHGAWR----------------PSEA 642
            :.|:  ..|:|...|..:.....:|:||: :|...:|| .|||:.                |.:.
  Rat   713 KSSDFVVLKQLLPLLEKVSNTYPDPVIQELAVDLRITISTHGAFSTEAVSTAAQSTLNKKDPEQK 777

  Fly   643 VKIQ---------------------PFQRARSLIE-------------------------EKQSH 661
            :|.|                     |.:..:...|                         :.|..
  Rat   778 IKEQRQTSYDASTEGTQNRPEQEQNPLRTGQGSSEPCTATSQPPGNITTEQFREVLLSACDPQVP 842

  Fly   662 MQVYGIQMMIDLLKKRDPATLAQGQLIIALALTTLKDKESYTFLNCVRLFVSLVHVMESDVL--- 723
            .:...::.:...:::|:...|.:.:.::.:.|..|:.::|:.:|:.::....|..|...::|
  Rat   843 TRAAALRTLSRWVEQREGRALEEQKKLLQIFLENLEHEDSFVYLSAIQGVALLSDVYPEEILVDL 907

  Fly   724 ----DKLSDEYLSETAHLDYRLVVGEAILKVAQELGPLCFRYKAVLLNCFMYGSRSPVHEFRMSA 784
                |...|::..||     |:.|||.::::.:.||.:..:|:..|::.|:.|.:.|....|.|:
  Rat   908 LARYDSSKDKHTPET-----RMKVGEVLMRIVRALGDMVSKYREPLIHTFLRGVKDPDGAHRASS 967

  Fly   785 FANLAQLCRLLAFQVQNFFHELLQLVNSELTTGGYVPSKRAAVLVLAELLNGM-----ENLLDYQ 844
            .:||.:||:.|.|.:....||:...:.:...|...|..:||||.|:..||.|:     |.|.|
  Rat   968 LSNLGELCQRLDFLLGPVVHEVTICLTAVAKTDTDVQVRRAAVHVVVLLLRGLSQKATEVLSD-- 1030

  Fly   845 EMLLPIYRLLK---AIEADESCDPQMRQHAANGLKILNKKCTKLIQSALEE------------KS 894
             :|..:|.|||   .:|.|:....|                   .|.||||            :.
  Rat  1031 -VLKDLYHLLKHVVRLEPDDVAKIQ-------------------AQLALEELDEIMRNFLFPPQK 1075

  Fly   895 LQKQIKVL 902
            |:|:|.||
  Rat  1076 LEKKIMVL 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango6	NP_609922.2	RTP1_C1	650..750	CDD:287349	19/131 (15%)
Tango6	XP_226428.6	RTP1_C1	831..934	CDD:287349	30/102 (29%)
		HEAT repeat	869..897	CDD:293787	10/27 (37%)
		HEAT repeat	947..973	CDD:293787	8/28 (29%)
		RTP1_C2	1032..1064	CDD:287297

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341719
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4653
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D365063at33208
OrthoFinder	1	1.000	-	-		FOG0004138
OrthoInspector	1	1.000	-	-		oto95869
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR20959
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.900