Protein Alignment Tango6 and tango6

DIOPT Version :10

• Sequence 1: NP_609922.2
• Gene: Tango6 / 35155
• FlyBaseID: FBgn0032728
• Length: 921
• Species: Drosophila melanogaster
• Sequence 2: XP_002936058.2
• Gene: tango6 / 100487721
• XenbaseID: XB-GENE-6044490
• Length: 1050
• Species: Xenopus tropicalis
• Alignment Length: 785
• Identity: 167/785 - (21%)
• Similarity: 322/785 - (41%)
• Gaps: 174/785 - (22%)

  Fly   206 WQYESKADFFRNILLFKATTLCP----TLAQLLHR---QLLGKLHLPQGFASLVEALHQNPNVNS 263
            |:   |.|....||:     .||    |:.:...:   |:|..||:...|              :
 Frog   351 WE---KCDAIARILV-----SCPQQSLTVEEYYQKVCPQILDLLHIQDPF--------------T 393

  Fly   264 SRNAEIVAS---IVARKGFSQLAQEKMVLQVLE-YCKFYLQNADKMCAGVLSLRRLYDLSDTNQK 324
            :|..:.||:   :...:...|||::.::|.||| ..::.|...:.:.|...:|....:||...:.
 Frog   394 ARQFQRVATEAFLAIGQAEPQLAEKHLILPVLEPLLRWTLAPQESVSAPGHTLVTENELSQCLED 458

  Fly   325 LIKEILF--KHWETLCNPEDIINGLIL---------MDH-QELCNRILLWQHLFCSSTVACLPSN 377
            ::|..:.  |...||.:..:.:...:.         :.| :..|..:|||  ....|...|..|:
 Frog   459 IMKVFVVGNKPTPTLLHYTNKVLPAVFCLYCFARQNVSHLRSPCQDVLLW--YLDKSERECAVSS 521

  Fly   378 LL--------VPYLPLLLQLYDGLPMELPASSQISAIILRCLDNREMKNELPAILQKLFKWEIEK 434
            |.        :|.||...::       .|||...:.:.:|   .:...::..|:.:|: .||
 Frog   522 LAGLSGIDTSLPSLPKYFEI-------KPASHGGAIVKVR---EKYSADDDDALYEKV-SWE--- 572

  Fly   435 EPPWK--CLNPRIIILPS------------MNTTQIQVKVAHKDHLADH-----DMGRILPGLLT 480
              .|:  ||...:.:.||            .|...:.|....::..:.|     |:.|.|
 Frog   573 --QWRTECLVELLSLSPSRGLAADFFLLCLKNLIPLSVGTDQEEPASCHGINLLDLERRL----- 630

  Fly   481 SSSHHSLTCKV-FLSLLGFIAKQINDKSSASVDFISSEAELKDFLHSKYQLK-LDLLIALNQMVA 543
            :.||.|...:: .|.:|..:.::|:|.....|.      ::.:|::...:.. ..|..:....||
 Frog   631 AMSHESQEKQLQLLQVLSVLCEKISDSIFTDVQ------QVVEFVYVTLERSCASLAFSEGGTVA 689

  Fly   544 HQPLRAQLS-----------------QHTKELLHILKDL-LVHRSREQDTTDQILLLVLNLLQEI 590
            .|.|...:.                 .|.|:||.:|:.: |.|       .|.::..:...|:..
 Frog   690 SQTLSMAMGLVAAMLGGAVMLTSSDFGHLKKLLPVLERVSLSH-------LDPVIQELAKDLRVS 747

  Fly   591 LEGSENIQL-SEACKELKEQLHLL-------GTRSSNPLI-QQSVKSLLTIIHGAWRPSEAVKIQ 646
            :.....:|| :..|:: |.:.|.:       .|:::||:. ||:.|.:|........|:.|.
 Frog   748 IATHCAVQLPNRTCQD-KAKAHDIDNKQSKHDTKTNNPVADQQNFKVMLNSARDTDIPTRAA--- 808

  Fly   647 PFQRARSLIEEKQSHMQVYGIQMMIDLLKKRDPATLAQGQLIIALALTTLKDKESYTFLNCVRLF 711
                               .::.:..||::::|..|...:.::.|.|..|..::|:.:|:.::..
 Frog   809 -------------------ALRTLTHLLEQKNPMALEHKEQLLQLFLENLDQEDSFVYLSAIQGV 854

  Fly   712 VSLVHVMESDVLDKLSDEY--LSETAHLDY----RLVVGEAILKVAQELGPLCFRYKAVLLNCFM 770
            ..|...:...||..|..:|  .:.|.|..:    ::.||||:::..:.||.|..:||.:|::.|:
 Frog   855 AVLSGEIPECVLPVLVAQYGNTAPTEHTGHSPETKIKVGEALMRCTRVLGNLVLQYKDLLIHAFL 919

  Fly   771 YGSRSPVHEFRMSAFANLAQLCRLLAFQVQNFFHELLQLVNSELTTGGYVPSKRAAVLVLAELLN 835
            .||:......|.|:.:||.:||:.|.|.:....||:...:.:.:.|......:|||:.|:..||.
 Frog   920 RGSKDQDSSLRASSLSNLGELCQHLQFSLGTVVHEISSCLCAVVRTDPEAQVRRAAIHVVVLLLR 984

  Fly   836 GMENLLD--YQEMLLPIYRLLKAIEADESCDPQMRQHAANGLKILNKKCTKLIQSAL-EEKSLQK 897
            |:.....  .:::||.:|||||.:...|: |.....||..||:.|:    .::::.| .::.|:|
 Frog   985 GLSEKATEVLRDVLLDLYRLLKFVVQCET-DSVSVLHAQLGLEELD----SIMRAVLFPQQKLEK 1044

  Fly   898 QIKVL 902
            :|.||
 Frog  1045 KIVVL 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tango6	NP_609922.2	RTP1_C1	648..757	CDD:463059	22/114 (19%)
		RTP1_C2	846..879	CDD:431206	13/32 (41%)
tango6	XP_002936058.2	RTP1_C1	791..906	CDD:463059	26/136 (19%)
		HEAT repeat	791..816	CDD:293787	4/46 (9%)
		HEAT repeat	831..859	CDD:293787	6/27 (22%)
		HEAT repeat	864..902	CDD:293787	10/37 (27%)
		HEAT repeat	913..939	CDD:293787	8/25 (32%)
		HEAT repeat	956..982	CDD:293787	5/25 (20%)
		RTP1_C2	997..1029	CDD:431206	13/32 (41%)