Protein Alignment Nak and STK16

DIOPT Version :10

• Sequence 1: NP_477165.1
• Gene: Nak / 35154
• FlyBaseID: FBgn0015772
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: NP_001008910.1
• Gene: STK16 / 8576
• HGNCID: 11394
• Length: 305
• Species: Homo sapiens
• Alignment Length: 311
• Identity: 98/311 - (31%)
• Similarity: 142/311 - (45%)
• Gaps: 36/311 - (11%)

  Fly    43 RVTVTVED-------VLAEGGFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIAS 100
            |.||.:::       .|.||||:.|.|..|...|..    |||||:..:.:.|...|:||..: .
Human    10 RGTVIIDNKRYLFIQKLGEGGFSYVDLVEGLHDGHF----YALKRILCHEQQDREEAQREADM-H 69

  Fly   101 NLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCKHHMLAMMNARLHVG---FTEPEVLNIFCDIA 162
            .|..|.||:..|...:...| ...|..||:|:.|...|.....||...   .||.::|.:...|.
Human    70 RLFNHPNILRLVAYCLRERG-AKHEAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGIC 133

  Fly   163 EAVSRLH---YCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQ-QHGVTVVQEEIQKY 223
            ..:..:|   |.     |||||..|||..|.|..||.|.||.....::.: ......:|:...:.
Human   134 RGLEAIHAKGYA-----HRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQR 193

  Fly   224 TTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPF------GES-TLAIQNGQFSIPD 281
            .|:||||||:..:.....|..:.|:|:|||:||.:.|...|:      |:| .||:|| |.|||.
Human   194 CTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQN-QLSIPQ 257

  Fly   282 SSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPI 332
            |.::|..:.||:..|:..|..:||:|..:..   :|.....|....|.|.|
Human   258 SPRHSSALRQLLNSMMTVDPHQRPHIPLLLS---QLEALQPPAPGQHTTQI 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nak	NP_477165.1	STKc_NAK_like	42..319	CDD:270939	94/296 (32%)
		DUF1633	<438..>619	CDD:116408
STK16	NP_001008910.1	STKc_16	19..295	CDD:270888	91/290 (31%)
		Activation loop	166..202		9/35 (26%)