Protein Alignment Nak and ARK1

DIOPT Version :9

• Sequence 1: NP_477165.1
• Gene: Nak / 35154
• FlyBaseID: FBgn0015772
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: NP_014378.1
• Gene: ARK1 / 855711
• SGDID: S000004965
• Length: 638
• Species: Saccharomyces cerevisiae
• Alignment Length: 675
• Identity: 179/675 - (26%)
• Similarity: 300/675 - (44%)
• Gaps: 107/675 - (15%)

  Fly    35 VGKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATKYA-LKRMYVNNEHDLNVAKREIQI 98
            ||...|||...|.:...|..||||.|:.|..|.....|.:..| |||:.|.::..||..:.|:..
Yeast    11 VGTQLTVGSHQVEIIKYLTSGGFAQVYSALINPPDPHSNSSVACLKRVIVPDKPSLNTLRAEVDA 75

  Fly    99 ASNLSGHKNIIGYVDSSITPT--GNGVCEVLLLMPYCKH-HMLAMMNARLHVGFTEPEVLNIFCD 160
            ...|..::.::.|:||.....  .||..||.:||.||:. .::..||.||.....|.|:|.|...
Yeast    76 MRLLKNNRYVVSYIDSHAAKAMLHNGSYEVFVLMEYCERGGLIDFMNTRLQNRLHEFEILQIMSQ 140

  Fly   161 IAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSATAKTLNPQQHG--VTVVQEEIQKY 223
            :.:.|:.:|..|.|:||||:|:||:|.:....:.||||||... .:.|.::.  ::.||::|.|.
Yeast   141 VTQGVAAMHALQPPLIHRDIKIENVLISANNEYKLCDFGSVCG-IIRPPRNSQELSYVQQDILKN 204

  Fly   224 TTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLPFGE-STLAIQNGQFSIPDSSKYSK 287
            ||..||:|||||.:.|..|..|:||||||..|||||:::.||.: ..|||.:|:|..|....||:
Yeast   205 TTAQYRSPEMIDTFRGLPIDEKSDIWALGIFLYKLCYYTTPFEKGGDLAILSGKFEFPLYPNYSE 269

  Fly   288 GMHQLIKYMLEPDMEKRPNIWQVCEVAFRLAGKDNPVQNLHKTPIPNFDLLVVPPFES-----EA 347
            .:..||:.:|..|...|||::|       |..:.:.:||:   |.|..|:.||....|     |.
Yeast   270 QLKGLIRDILVQDPRHRPNVYQ-------LLKRISIMQNV---PCPINDIQVVQAPSSHLNLTEL 324

  Fly   348 KRISAAASKAAKAQNVSVVEAGTSVAPRSRPKGSSSVH-GGNPLGLGLPPSPSPRQ-----NITS 406
            .::||       .||:..:.:.|:: ..:.|..:..:. ..|.....:.|:..|.|     :.::
Yeast   325 HQLSA-------TQNILSLNSPTTM-ENTMPNATFQISMADNTTTAQMHPNRKPSQIAYDASFSN 381

  Fly   407 PQPQPQPVVEQFQANFPAM-PPAVPPPPQAVTP-----AAPAASKLFES-SGYPDPFNEPAAAVI 464
            .....||:.::.|..:.|: ||.|.|...:|:.     .|.:|:||.:: ......|.:..:...
Yeast   382 SAKGSQPLFDKSQNMYHALDPPLVEPLASSVSNNDNELKANSATKLKQAIVSEAHTFRQNNSIDF 446

  Fly   465 PTE-FLPAAEEPNK---EEVPQDLNVIAGTPTKSMLTPPKPSGGGGHRRNVSDTSAFNKTFANET 525
            |.: .:|..|:.:.   |....|::.:  ..|:|:       |....|.|:....:..::..:.:
Yeast   447 PLQNIIPQYEDSSSSSDESYSGDVDEL--KKTRSL-------GSYSTRGNIKKNQSVKESLTSSS 502

  Fly   526 --SQFLAPFNNNLAAMGDGQQTLASAASNPGIYASSTANSAAVSISELMKPG-----------QT 577
              .....|.:..:....:         ::|  :.|:..|:...|..:|.||.           :.
Yeast   503 LPGTSFTPTSTKVNLKHE---------NSP--FKSTFVNTIDNSKDDLNKPSYEDLDVSKQNLKN 556

  Fly   578 AVEKR-VEAWNPFEEEQPFSQMTEDHIFE-AEFDKIRQRGSQGSITAKSASTTSTLTPTEQIPSA 640
            ::::| ::..|..||.....:|::..:.| .|.||.....|.|.| :|...|..|
Yeast   557 SIQQRMIDKLNSSEESFNARKMSKVKLHEKGEIDKPTMLKSSGPI-SKDKKTKPT---------- 610

  Fly   641 VVAPVTAAPGAVPPPPIAAAVSPYP 665
                         |||..:.:.|.|
Yeast   611 -------------PPPKPSHLKPKP 622

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nak	NP_477165.1	STKc_NAK_like	42..319	CDD:270939	104/283 (37%)
		S_TKc	47..312	CDD:214567	101/271 (37%)
ARK1	NP_014378.1	STKc_NAK_like	18..301	CDD:270939	104/290 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	174	1.000	Domainoid score	I743
eggNOG	1	0.900	-	-		E1_KOG1989
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2048
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001273
OrthoInspector	1	1.000	-	-		otm46860
orthoMCL	1	0.900	-	-		OOG6_101386
Panther	1	1.100	-	-	O	PTHR22967
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R972
SonicParanoid	1	1.000	-	-		X882
TreeFam	1	0.960	-	-
	12	11.750