Protein Alignment Nak and Bmp2k

DIOPT Version :9

• Sequence 1: NP_477165.1
• Gene: Nak / 35154
• FlyBaseID: FBgn0015772
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: XP_038948586.1
• Gene: Bmp2k / 498333
• RGDID: 1564828
• Length: 1122
• Species: Rattus norvegicus
• Alignment Length: 1445
• Identity: 401/1445 - (27%)
• Similarity: 558/1445 - (38%)
• Gaps: 496/1445 - (34%)

  Fly     1 MKKILSKFERNENSRLENPPNSSSSSSSNEKNSFVG----------KVFTVGRVTVTVEDVLAEG 55
            ||| .|:..::|.|       ...:::.....|.:|          :||.|||..||:|:.||||
  Rat     1 MKK-FSRMPKSEGS-------GGGAAAGGAAGSGLGGGFGSSSMGVRVFAVGRYQVTLEESLAEG 57

  Fly    56 GFAMVFLARGNGGGSSSATKYALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTG 120
            ||:.|||.|.:.|     .:.|||||||||..|||:.||||.|...|||||||:||:|.::....
  Rat    58 GFSTVFLVRTHSG-----IRCALKRMYVNNTPDLNICKREITIMKELSGHKNIVGYLDCAVNSIS 117

  Fly   121 NGVCEVLLLMPYCK-HHMLAMMNARLHVGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVEN 184
            :.|.|||:||.||: ..::..||.:|..||||.|||.||||..|||:|||.|:||||||||||||
  Rat   118 DNVWEVLILMEYCRAGQVVNQMNKKLQTGFTESEVLQIFCDTCEAVARLHQCKTPIIHRDLKVEN 182

  Fly   185 ILQTDAGNFVLCDFGSATAKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIW 249
            ||..||||:|||||||||.|.||||:.||.||:|||:|||||||||||||:|||||.||||||||
  Rat   183 ILLNDAGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIW 247

  Fly   250 ALGCMLYKLCFFSLPFGESTLAIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQVCEVA 314
            ||||:|||||||:||||||.:||.:|.|:|||:|:||..:|.||::|||||.|.||:|:||...|
  Rat   248 ALGCLLYKLCFFALPFGESQVAICDGSFTIPDNSRYSHNVHCLIRFMLEPDPEHRPDIFQVSYFA 312

  Fly   315 FRLAGKDNPVQNLHKTPIPNFDLLVVPPFESEAKRISAAASKAAKAQNVSVV-EAGTSVAPRSRP 378
            |:.|.||.||.|::.:.:|:  .|..|...:||    ||.....||:....: ...||:|||.||
  Rat   313 FKFAKKDCPVSNINNSILPS--TLPEPMTATEA----AARKSQMKARITDTIGPTETSIAPRQRP 371

  Fly   379 KGSSSV---------HGGNPLGLGLP-------PSPSPR----------QNITSPQPQPQPVVEQ 417
            |.:|:.         ....|:.:..|       |..:.|          |..|...||...|::|
  Rat   372 KANSTAAISSVLTIQSSATPVKVPAPGEFSNHKPKGALRPGNGSDILMVQGPTQQPPQQHRVLQQ 436

  Fly   418 FQA-----------NFPAMPPAVPPPPQAVTPAAPAASKLFE----------------------- 448
            .|.           ..|..........|..........:|.:
  Rat   437 LQQGDWRLQQLHLHRHPQQQQQQQQQQQQQQQQQQQQQQLLQNAYLQQYQHAMHQQQILQQQFLM 501

  Fly   449 ---------SSGYPDPFNEPAAAVIPTEFLPAAEEPNKEEVPQDLNVIAGTPTKSMLTPPKPSGG 504
                     :|.||....:...|::..:.|...::|.::..|:            .||.|:
  Rat   502 HSVYQPQPLASQYPTMMQQYQQALLQQQMLAHHQQPAQQVSPE------------YLTSPQ---- 550

  Fly   505 GGHRRNVSDTSAFNKTFANETSQFLAPFNNNLAAMGDGQQTLASAASNPGIYASSTANSAAVSIS 569
                               |.|..|||:.::|.|             ..|....|:..:.:.|::
  Rat   551 -------------------EFSPALAPYGSSLPA-------------QVGTIVDSSYGATSRSVA 583

  Fly   570 ELMKPGQTAVEKRV------EAWNPFEEEQPFSQMTEDHIFEAEFDKIRQRGSQGSITAKSASTT 628
            |.........:|.:      ..||||.|:. ||::||:.:.:.|||.:|            ::..
  Rat   584 EKEAVANFTNQKTISHPPDMSGWNPFGEDN-FSKLTEEELLDREFDLLR------------SNRL 635

  Fly   629 STLTPTEQIPSAVVAPVTAAPGAVPPPPIAAAVSPYPSQVSEDPFGSAPFSLPPGLREKASSLRK 693
            ...||:::              .|.|||     :|: |:..|:||.|.||....|..||
  Rat   636 GESTPSDK--------------NVDPPP-----APH-SRPPEEPFASVPFISHSGSPEK------ 674

  Fly   694 TGAKFIGVSSGGTGGGVATPIGLVAGGANTATSSNSSKWMLSPTLEVSSEEKTSLISKLKTDSEC 758
                                        .|..|.|.......||...||    |.|.|
  Rat   675 ----------------------------KTEHSPNQKNITAHPTKNGSS----SPICK------- 700

  Fly   759 GIPGAVGGAGEGVSGYVKLPVEDRNKYEKLRSKDQPTSDDSDSEASEFFQQDSDEGGGGIFRQMQ 823
                    ||:..|   :.||        :|...|..:|:|:||    |:.|
  Rat   701 --------AGQKTS---ENPV--------VRGHAQKGNDESESE----FESD------------- 729

  Fly   824 MVTSNLPETIHKIQQVAYHKVDKTAHLPIVKKLRDKTKKPTTAAHQAAQQLNLMAAAVAAQAEEA 888
                                                  .|:..:.:..|:
  Rat   730 --------------------------------------PPSPKSSEEEQE--------------- 741

  Fly   889 AKAAESDGDSIGSASDLRAEDDDLFDENPRQTQAKQRRPLPTEMDGISESVKTCSSSAYHAECES 953
                  |.|:.|...|.  .|:|...||      ...|||..:.:...|..|..|.|    |||.
  Rat   742 ------DEDAQGEHGDF--NDEDTEPEN------LGHRPLLMDSEDEEEDDKHSSDS----ECEQ 788

  Fly   954 VTTHEDDVRSRVVVKVRMRKKDRALVTATGDPSAPSEELSPTSSDLLHKFGDRPLLL--DDELDY 1016
            ......:..|     :|..|...|...|:.....||:|..        .||..|...  ..||.:
  Rat   789 AKAKGGESSS-----LRRNKPGGAPEPASSPALTPSQEFD--------VFGAVPFFAVPAPELQH 840

  Fly  1017 -GSGESKSSTESPVAPILPTNPDVQESEEDVFALAPFKLPVGVPLKRKTKPKAKPKPSEPEMWTS 1080
             |||:|.|....|           ::.|.|||..|||...|.|......:|..:|.|:.|.
  Rat   841 RGSGKSVSQQMFP-----------EQEEYDVFTKAPFSKKVTVQDWPAVRPDTRPLPARPR---- 890

  Fly  1081 TPVKSAAVGDPSTNFASFPAQLTPTNNVGNSAQLDEFNEPIFNPFQENAQNTQSGETNQCDLFGL 1145
                                            .:|.|....|.||...|..::|.|    |:|||
  Rat   891 --------------------------------SVDIFGSTPFQPFSTAASKSESKE----DVFGL 919

  Fly  1146 EPFPQV---------------------------------------------------IRTIEQNP 1159
            .||.::                                                   .||.|:..
  Rat   920 VPFEEITGSQQQQQKVKQRSLQKLSSRQRRTKQDVSKSNGKRHHGTPTSAKKPLKPPYRTPERAR 984

  Fly  1160 QHHQIHQFPSHNNNN--NVIKVPASVSVALP-----ASV-PVSVSVNS-------SAPQL----- 1204
            :|.::.:..|.::|.  .:.....::||||.     ||| |...|:..       ..|.|
  Rat   985 RHKRVGRRDSQSSNEFLTISDSKENISVALTDGKDRASVLPPDESLLDPFGAKPFHPPDLWHQTH 1049

  Fly  1205 -----VTINHSIIINKTPEPPMNYNNNNNNQTAKSSGTSSVYVNVPSFSSMSTSSC---SINQPQ 1261
                 :.::|:.|:...|          ...:...|..|:..:.:..|.::..:..   |::..|
  Rat  1050 QGLSDICVDHTAILPGRP----------RQNSVHGSFHSADALRMDDFGAVPFTELVVQSVSPQQ 1104

  Fly  1262 SSPAAVIPV-QAPLP 1275
            |.|..:.|. .||.|
  Rat  1105 SQPVELDPFGAAPFP 1119

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nak	NP_477165.1	STKc_NAK_like	42..319	CDD:270939	180/277 (65%)
		S_TKc	47..312	CDD:214567	175/265 (66%)
Bmp2k	XP_038948586.1	STKc_NAK_like	44..317	CDD:270939	180/277 (65%)
		BMP2K_C	856..1122	CDD:405873	58/314 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	348	1.000	Domainoid score	I1000
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001273
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101386
Panther	1	1.100	-	-	LDO	PTHR22967
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X882
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.000