Protein Alignment Nak and ppk38

DIOPT Version :9

• Sequence 1: NP_477165.1
• Gene: Nak / 35154
• FlyBaseID: FBgn0015772
• Length: 1488
• Species: Drosophila melanogaster
• Sequence 2: NP_588555.1
• Gene: ppk38 / 2539030
• PomBaseID: SPCP1E11.02
• Length: 650
• Species: Schizosaccharomyces pombe
• Alignment Length: 673
• Identity: 193/673 - (28%)
• Similarity: 285/673 - (42%)
• Gaps: 144/673 - (21%)

  Fly    11 NENSRLENPPNSSSSSSSNEKNSFVGKVFTVGRVTVTVEDVLAEGGFAMVFLARGNGGGSSSATK 75
            ||.:.....|.||..|....    ||...||.:.:|||:..||||||:.|:|.:....| ....:
pombe     2 NETNNTSLLPVSSLPSGLLP----VGFSCTVEKFSVTVKRYLAEGGFSHVYLVQLVFPG-KPPFE 61

  Fly    76 YALKRMYVNNEHDLNVAKREIQIASNLSGHKNIIGYVDSSITPTGNGVCEVLLLMPYCK-HHMLA 139
            ..|||::..:...|.....|::....:|..|..:.|..|....|.....|||:|:.||. ..::.
pombe    62 AVLKRIFATDAMALRAVHEEVRTMKLVSNQKRCVSYYGSEFFRTSKNQFEVLVLLEYCPCGGLID 126

  Fly   140 MMNARLHVGFTEPEVLNIFCDIAEAVSRLHYCQTPIIHRDLKVENILQTDAGNFVLCDFGSAT-- 202
            .:|.||.|..:|.|:|.|..|:.|||:.:||.:.|:||||||:||:|.....::.|||||||.
pombe   127 FLNTRLQVRLSEQEILKIASDVTEAVAVMHYLKPPLIHRDLKIENVLLAAPNSYKLCDFGSACHP 191

  Fly   203 ---AKTLNPQQHGVTVVQEEIQKYTTLSYRAPEMIDLYGGKSITTKADIWALGCMLYKLCFFSLP 264
               |||....:.    ::.:|:|:||..||.||||:::.|..|..|:||||||.:.||||:::.|
pombe   192 IPGAKTAAEAKQ----LEYDIEKFTTWQYRCPEMINVHKGFGIDEKSDIWALGVLFYKLCYYTTP 252

  Fly   265 FGESTL-AIQNGQFSIPDSSKYSKGMHQLIKYMLEPDMEKRPNIWQV-CEVAFRLAGKDNPVQNL 327
            |....| ||.|..::.|....||..:.:||..:|:....:||||:|. ||:.           .:
pombe   253 FEHQGLAAIMNVSYAFPTFPPYSDRLKRLISTLLQQYPWQRPNIYQTFCEIC-----------KM 306

  Fly   328 HKTPIPNFDLLVVPPFESEAKRISAA-------ASKAAKAQNVSVVEAGTSVAPR---------- 375
            ...||..:|:.       ..|.:|:.       ...|:|.:|..:.::.:||.|:
pombe   307 RNVPIHIYDIY-------NGKNVSSCNPSGSEYLQHASKLENSGIHQSKSSVFPQPASAMKPMAS 364

  Fly   376 -------SRPKGSSSVHGGNPLGLGLPPSPSPRQNI---TSPQPQPQPVVEQFQANFPAMPPAV- 429
                   |.|..|:..|..|    |...||..|.:.   ||..|..|.:...|:....|.|...
pombe   365 PMLPNVNSMPYLSNGDHNNN----GNTSSPVSRFSYGQHTSNVPSTQKLPSNFRVTQGAPPSHTY 425

  Fly   430 -PPPP----QAVTPAAPAASKLFESSGYPDPFNEPAAAVIPTEFLPAAEEPNKEEV--------- 480
             ||||    ..::|..|..|.|..:.   |.|:..|...:||          .|.|
pombe   426 GPPPPVQPKPKISPTTPRLSTLALAD---DMFSSTAKETVPT----------NEAVFTGDVKSFD 477

  Fly   481 PQDLNVIAGTPTKSMLTPPKPSGGGGHRRNV-------SDTSAFNKTFA---------------N 523
            .|:.|:|...|..:.....||      |.:|       :.||:.||..|               |
pombe   478 SQESNIIESEPLSASNASGKP------RTSVNRLVDRYNHTSSLNKVAAAPAPVPKPVNLKSVEN 536

  Fly   524 ETSQFLAPFNNNL----AAMGDGQQTLASA-----ASNPGIYASSTANSAAVSISELMKPGQTAV 579
            ..:...||..::|    |.:|.|:....|.     |:..|:.....:.|.||:...:.||
pombe   537 PQNNISAPTPSSLQSSNAPVGLGEVESKSVPPTNMATERGVVGRRASMSIAVNARRVSKP----- 596

  Fly   580 EKRVEAWNPFEE------EQPFS 596
            ||  |..||..|      |:|.|
pombe   597 EK--EHTNPNAEQGDVIPEKPMS 617

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nak	NP_477165.1	STKc_NAK_like	42..319	CDD:270939	104/284 (37%)
		S_TKc	47..312	CDD:214567	101/272 (37%)
ppk38	NP_588555.1	PKc_like	31..308	CDD:304357	104/292 (36%)
		S_TKc	34..298	CDD:214567	100/268 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	190	1.000	Domainoid score	I725
eggNOG	1	0.900	-	-		E1_KOG1989
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001273
OrthoInspector	1	1.000	-	-		otm47314
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22967
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R972
SonicParanoid	1	1.000	-	-		X882
TreeFam	1	0.960	-	-
	10	9.900