DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10623 and HMT2

DIOPT Version :9

Sequence 1:	NP_001286073.1	Gene:	CG10623 / 35153	FlyBaseID:	FBgn0032727	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001319825.1	Gene:	HMT2 / 825500	AraportID:	AT3G63250	Length:	333	Species:	Arabidopsis thaliana

Alignment Length:	319	Identity:	111/319 - (34%)
Similarity:	185/319 - (57%)	Gaps:	32/319 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGFVKYLG 83
            ||.:::..::..:.  .||||.::...|:|..:...|||:|..|||||.:.:||::::|| :..|
plant    24 GGLATEFERHGADL--NDPLWSAKCLVTSPHLIHTVHLDYLEAGADIISSASYQATIQGF-EAKG 85

  Fly    84 VTRERGVELIQKSVQLAKQAKEQYLSEIGSEAE------SALP-LIMGSIGPYGAYLHDGSEYTG 141
            .:||....|::|||::|.:|:..|..:.|:.:.      ...| |:..|:|.|||||.|||||:|
plant    86 FSREESESLLKKSVEIATEARNSYYDKCGTSSSMDDKILKKRPILVAASVGSYGAYLADGSEYSG 150

  Fly   142 NYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKF--WVSLQC 204
            .|.|.::.|:|:.:|:.|:::...:|.|.:|.||:|..:||:|..:|:.:.  |.|.  |.|...
plant   151 IYGDSITLEKLKDFHRRRLQVLAESGADLIAFETIPNKIEAQAFADLLEEG--DVKIPGWFSFNS 213

  Fly   205 MDEKHMASGENFAEAALSLWRLVQSRKAEN--RLLGIGLNCVNPLFVTPLLSSLTKVAGSDRIPL 267
            .|..::.||::..| .:|:        |||  :::.:|:||..|.|:..|:..:.||...   |:
plant   214 KDGVNVVSGDSIKE-CISI--------AENCEKVVAVGINCTPPRFIEGLVLEIEKVTSK---PI 266

  Fly   268 VVYSNRGEIYDVEQGDW---TGTG-EEVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRK 322
            :||.|.||.||.::.:|   ||.| |:.|.:|.:|:..||.::|||||..||.:.||.|
plant   267 LVYPNSGESYDADRKEWVENTGVGDEDFVSYVEKWMDAGVSLLGGCCRTTPTTIRAIHK 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10623	NP_001286073.1	S-methyl_trans	9..322	CDD:304616	110/317 (35%)
HMT2	NP_001319825.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	195	1.000	Domainoid score	I909
eggNOG	1	0.900	-	-		E1_COG0646
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1324
OMA	1	1.010	-	-		QHG62632
OrthoDB	1	1.010	-	-		D731388at2759
OrthoFinder	1	1.000	-	-		FOG0002464
OrthoInspector	1	1.000	-	-		mtm1099
orthoMCL	1	0.900	-	-		OOG6_102920
Panther	1	1.100	-	-	O	PTHR46015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3176
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840