Protein Alignment Bhmt and Bhmt2

DIOPT Version :10

• Sequence 1: NP_609921.1
• Gene: Bhmt / 35153
• FlyBaseID: FBgn0032727
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_075022.2
• Gene: Bhmt2 / 64918
• MGIID: 1891379
• Length: 363
• Species: Mus musculus
• Alignment Length: 356
• Identity: 76/356 - (21%)
• Similarity: 115/356 - (32%)
• Gaps: 117/356 - (32%)

  Fly    10 DTKPILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSS 74
            |:..::|...||...|.|....|..   ||.......:|.||.|.|.:|||.|||::.|.|:.::
Mouse    18 DSGEVVVGDSGFLFTLEKRGFVKAG---LWTPEAVVEHPSAVRQLHTEFLRAGADVLQTFTFSAT 79

  Fly    75 VEGFVKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAESALPLIMGSIGPYGAYLHDGSEY 139
            .:..............:|.|:..                             |..||.:..|...
Mouse    80 EDNMASKWEAVNAAACDLAQEVA-----------------------------GGGGALVAGGICQ 115

  Fly   140 TGNYADKMSKEELRAWH--KTRIEICLAAGVDGLALETLPCLMEAEAVTELVL------------ 190
            |..|  |..|:|.|..:  :.::|:.....||.|..|....:.||....|::.
Mouse   116 TSLY--KYHKDETRIKNIFRLQLEVFARKNVDFLIAEYFEHVEEAVWAVEVLREVGAPVAVTMCI 178

  Fly   191 -------DNFP-----------------DAKF--WVSLQCMDEKHMASGENFAEAALSLWRLVQS 229
                   |..|                 :.:|  |.|||.|  |.|..|  ..:|:|....:||
Mouse   179 GPEGDMHDVTPGECAVKLARAGADIIGVNCRFGPWTSLQTM--KLMKEG--LRDASLQAHLMVQ- 238

  Fly   230 RKAENRLLGIGLNCVNPLFVTPLLSSLTKVAGSDRIPLVVYSNRGEIYDVEQGDW-----TGTGE 289
                         |:.  |.||                  ...:|...|:.:..:     ..|..
Mouse   239 -------------CLG--FHTP------------------DCGKGGFVDLPEYPFGLEPRVATRW 270

  Fly   290 EVVKFVPEWIQLGVRIVGGCCRVYPTDVLAI 320
            ::.|:..|...||:|.:||||...|..:.||
Mouse   271 DIQKYAREAYNLGIRYIGGCCGFEPYHIRAI 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Bhmt	NP_609921.1	PRK07534	9..322	CDD:473986	76/356 (21%)
Bhmt2	NP_075022.2	S-methyl_trans	23..305	CDD:460598	75/351 (21%)