DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10623 and SPAC57A7.07c

DIOPT Version :9

Sequence 1:	NP_001286073.1	Gene:	CG10623 / 35153	FlyBaseID:	FBgn0032727	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_593374.1	Gene:	SPAC57A7.07c / 2542156	PomBaseID:	SPAC57A7.07c	Length:	308	Species:	Schizosaccharomyces pombe

Alignment Length:	320	Identity:	82/320 - (25%)
Similarity:	135/320 - (42%)	Gaps:	50/320 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGF 78
            :|:..||.::.|.| :.|.:....||.|......||.|::.|.:||: ..|||.|.|||.....:
pombe     1 MLMLDGGSTAILPK-LPESISESRLWTSEALVRYPEIVVKHHEEFLK-VCDIISTFTYQLDASIY 63

  Fly    79 VKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIG----SEAESALP--LIMGSIGPYGAYLHDGS 137
            .:     :..||.|           |:.|.:.||    :.....||  .|...:|.:.|.:....
pombe    64 DE-----KVEGVPL-----------KQVYANSIGLPVYAREHLGLPNKYIALCLGSHAATIPGCM 112

  Fly   138 EYTGNYADKMSKEELRAWHKTRIEICLAAG------VDGLALETLPCLMEAEAVTELVLDNFPDA 196
            ||...|......|.|..:||.|||...|:.      :|.:|.|:||.:.|||.|.:|:.|....:
pombe   113 EYKMIYDKPTDFEMLYNFHKNRIEAIQASNPKAFEKIDFIAFESLPHVTEAEVVCQLIQDMKGWS 177

  Fly   197 K-FWVSLQCMDEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLFVTPLLSSLTKVA 260
            | .|::..|.:...:....:.....||:        ..:.:.|||:||.:...:.|:...|:.:.
pombe   178 KRCWITCTCPERSTIERVSSIISKILSI--------NHDSIWGIGVNCFHLSLLEPIAKMLSSLL 234

  Fly   261 GSDRIPLVVYSNRGEIYDVEQGDWT-GTGEEVVKFVPEW---------IQLGVRIVGGCC 310
            .|: |..::|.:...:|....|.:: |:.:.......||         :..|..|:||||
pombe   235 PSN-ITAILYPDGRGLYQNPDGTFSPGSTDHPAPSPEEWSTITAKYSNLHNGNLILGGCC 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10623	NP_001286073.1	S-methyl_trans	9..322	CDD:304616	82/320 (26%)
SPAC57A7.07c	NP_593374.1	MHT1	1..308	CDD:224951	82/320 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	71	1.000	Domainoid score	I2618
eggNOG	1	0.900	-	-		E1_COG0646
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	71	1.000	Inparanoid score	I1916
OMA	1	1.010	-	-		QHG62632
OrthoFinder	1	1.000	-	-		FOG0002464
OrthoInspector	1	1.000	-	-		otm47136
orthoMCL	1	0.900	-	-		OOG6_102920
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2187
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.760