Protein Alignment CG10623 and BHMT2

DIOPT Version :9

• Sequence 1: NP_001286073.1
• Gene: CG10623 / 35153
• FlyBaseID: FBgn0032727
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_060084.2
• Gene: BHMT2 / 23743
• HGNCID: 1048
• Length: 363
• Species: Homo sapiens
• Alignment Length: 339
• Identity: 70/339 - (20%)
• Similarity: 122/339 - (35%)
• Gaps: 91/339 - (26%)

  Fly    14 ILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGF 78
            :::..|.|...|.|....|..   ||.......:|:||.|.|::|||.|::::.|.|:.:|.:..
Human    22 VVIGDGSFLITLEKRGYVKAG---LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQTFTFSASEDNM 83

  Fly    79 VKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGSEAESALPLIMGSIGPYGAYLHDGSEYTGNY 143
                   ..:..::...:..||:        |:..:.::   |:.|.|.....|
Human    84 -------ESKWEDVNAAACDLAR--------EVAGKGDA---LVAGGICQTSIY----------- 119

  Fly   144 ADKMSKEE--LRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCM- 205
              |..|:|  ::...:.::|:.....||.|..|....:.||....|::.::  |....|:: |:
Human   120 --KYQKDEARIKKLFRQQLEVFAWKNVDFLIAEYFEHVEEAVWAVEVLKES--DRPVAVTM-CIG 179

  Fly   206 ---DEKHMASGE---NFAEAALSLWRLVQSRKAENRLLGIGLNC-VNP----------------- 246
               |...:..||   ...:|..|:               :|:|| ..|
Human   180 PEGDMHDITPGECAVRLVKAGASI---------------VGVNCRFGPDTSLKTMELMKEGLEWA 229

  Fly   247 -----LFVTPLLSSLTKVAGSDRIPLVVYSNRGEIYDVEQGDWTGTGEEVVKFVPEWIQLGVRIV 306
                 |.|.||............:.|..|.     :.:|..  ..|..::.|:..|...||||.:
Human   230 GLKAHLMVQPLGFHAPDCGKEGFVDLPEYP-----FGLESR--VATRWDIQKYAREAYNLGVRYI 287

  Fly   307 GGCCRVYPTDVLAI 320
            ||||...|..:.||
Human   288 GGCCGFEPYHIRAI 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10623	NP_001286073.1	S-methyl_trans	9..322	CDD:304616	70/339 (21%)
BHMT2	NP_060084.2	S-methyl_trans	23..303	CDD:308273	70/338 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0646
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I5453
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.870