Protein Alignment CG10621 and BHMT

DIOPT Version :9

• Sequence 1: NP_001286071.1
• Gene: CG10621 / 35152
• FlyBaseID: FBgn0032726
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_001704.2
• Gene: BHMT / 635
• HGNCID: 1047
• Length: 406
• Species: Homo sapiens
• Alignment Length: 338
• Identity: 77/338 - (22%)
• Similarity: 115/338 - (34%)
• Gaps: 67/338 - (19%)

  Fly     6 VLVKDGGFGTQMTVHVGDSVDGDPLWSARFNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGY 70
            :::.||||  ...:.....|...| |:......:|.|:...|.:||:.|::::.|.|:.:|.|
Human    22 IVIGDGGF--VFALEKRGYVKAGP-WTPEAAVEHPEAVRQLHREFLRAGSNVMQTFTFYASED-- 81

  Fly    71 MEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYT 135
                :|:...:..|.|.:      .:|.....|..|:....||..|:..           |...|
Human    82 ----KLENRGNYVLEKIS------GQEVNEAACDIARQVADEGDALVAG-----------GVSQT 125

  Fly   136 GSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCK 200
            .||.......|:......::|..::..||.|..|......||...||.|......|   .|..|.
Human   126 PSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKPV---AATMCI 187

  Fly   201 DENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNC-----VHPKFVTPLFKSLNGDR----- 255
            ......||....:.        |.|..:.....|||||     :..|.|..:.:.|...|
Human   188 GPEGDLHGVPPGEC--------AVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARLKAHL 244

  Fly   256 ----------EVGEQ--IPLVVYPNSGEVYDVVNGWQGREHCVPLANYVPEWAQLGAKVIGGCCR 308
                      :..:|  |.|..:| .|....|...|.       :..|..|...||.:.|||||.
Human   245 MSQPLAYHTPDCNKQGFIDLPEFP-FGLEPRVATRWD-------IQKYAREAYNLGVRYIGGCCG 301

  Fly   309 TYARDIRHIGEAI 321
            .....||.|.|.:
Human   302 FEPYHIRAIAEEL 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10621	NP_001286071.1	mmuM	5..323	CDD:181899	77/338 (23%)
BHMT	NP_001704.2	S-methyl_trans	23..312	CDD:308273	76/333 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0646
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I5453
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8560
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.870