Protein Alignment CG10621 and MTR

DIOPT Version :10

• Sequence 1: NP_609920.1
• Gene: CG10621 / 35152
• FlyBaseID: FBgn0032726
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: XP_011542496.1
• Gene: MTR / 4548
• HGNCID: 7468
• Length: 1321
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 73/349 - (20%)
• Similarity: 128/349 - (36%)
• Gaps: 115/349 - (32%)

  Fly    27 GDPLWSARFNA-------TNPAAIISTHLDFLQNGADIILTNTYQSSVDGYMEYLELDEEQSIEL 84
            |:.::||..:|       .:|.:....:.::|..|||||.|||:.|:.....:|       .:|.
Human   111 GEHVFSAAPSAQGGDSTTCHPRSKTCRNPEYLLAGADIIETNTFSSTSIAQADY-------GLEH 168

  Fly    85 IKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIA-SIGPFGAHLHDGSEYTGSYADFVPAKEIT 148
            :...:.:......|...|    ::::|.|....:| ::||           |.......|:.|..
Human   169 LAYRMNMCSAGVARKAAE----EVTLQTGIKRFVAGALGP-----------TNKTLSVSPSVERP 218

  Fly   149 DWHRVRIEACLEA-----------GVDALAIETIPCQMEAE----ALVEMLCDDYPDVKFWVAFQ 198
            |:..:..:..:||           |||.|.||||.....|:    ||..:..:.|.....:::..
Human   219 DYRNITFDELVEAYQEQAKGLLDGGVDILLIETIFDTANAKAALFALQNLFEEKYAPRPIFISGT 283

  Fly   199 CKDEN--------------TLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFK 249
            ..|::              :::|||.                     |.||:||.
Human   284 IVDKSGRTLSGQTGEGFVISVSHGEP---------------------LCIGLNCA---------- 317

  Fly   250 SLNGDREVGEQIPLV---------VYPNSG-----EVYDVVNGWQGREHCVPLANYVPEWAQLG- 299
              .|..|:...|.::         .|||:|     ..||        |....:|.::.::|..|
Human   318 --LGAAEMRPFIEIIGKCTTAYVLCYPNAGLPNTFGDYD--------ETPSMMAKHLKDFAMDGL 372

  Fly   300 AKVIGGCCRTYARDIRHIGEAIRD 323
            ..::||||.:....||.|.||:::
Human   373 VNIVGGCCGSTPDHIREIAEAVKN 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10621	NP_609920.1	mmuM	5..323	CDD:181899	73/347 (21%)
MTR	XP_011542496.1	PHA03307	<25..>99	CDD:223039
		metH	140..1317	CDD:481230	68/320 (21%)