DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10621 and mtr

DIOPT Version :9

Sequence 1:	NP_001286071.1	Gene:	CG10621 / 35152	FlyBaseID:	FBgn0032726	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_932338.1	Gene:	mtr / 378847	ZFINID:	ZDB-GENE-031001-5	Length:	1263	Species:	Danio rerio

Alignment Length:	365	Identity:	90/365 - (24%)
Similarity:	151/365 - (41%)	Gaps:	101/365 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RVLVKDGGFGTQMTV-HVGD-------------SVDGDPLWSARFNATNPAAIISTHLDFLQNGA 55
            |:||.|||.||.:.. |:.:             |:.|:   :...:.|.|..|.|.|.::|:.||
Zfish    27 RILVLDGGMGTMIQQRHLEEEEFRGQEFKDHPKSLKGN---NDILSITQPDVIYSIHKEYLEAGA 88

  Fly    56 DIILTNTYQSSVDGYMEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIA- 119
            |||.|||:.|:.....:|..  |:.:..|.|.:..:|..|.:         .:|.|.|....:|
Zfish    89 DIIETNTFSSTSIAQADYGM--EDLAYRLNKASAEVARRAAD---------DVSAQTGCKRFVAG 142

  Fly   120 SIGPFGAHLHDGSEYTGSYADFVPAKEITDWHRV-----------RIEACLEAGVDALAIETIPC 173
            ::||           |.......|:.|..|:..:           :::..|:.|.|.|.:|||..
Zfish   143 ALGP-----------TNKTLSVSPSVERPDYRNITFDELVEAYAEQVKGLLDGGADVLLVETIFD 196

  Fly   174 QMEAEALVEMLCDDYPDVKFWVAFQC-----------KDENTLA--HGETFADAANAIWDLLAER 225
            ...|:|.:..:     |..|..:::.           |...||:  .||.|         :::..
Zfish   197 TANAKAALFAI-----DRLFEESYEARPVLISGTIVDKSGRTLSGQTGEAF---------VISVS 247

  Fly   226 NAQDKCLAIGVNC------VHPKFVTPLFKSLNGDREVGEQIPLVVYPNSGEVYDVVNGWQGREH 284
            :||..|  ||:||      :.| |:..:.||.:..        ::.|||:|    :.|.:.|.:.
Zfish   248 HAQPLC--IGLNCALGASEMRP-FIEAIGKSTSAF--------VICYPNAG----LPNTFGGYDE 297

  Fly   285 CVPL-ANYVPEWAQLG-AKVIGGCCRTYARDIRHIGEAIR 322
            ...: |.::.|:|..| ..::||||.|....||.|.|::|
Zfish   298 TPDVTAAHLKEFAVDGLVNIVGGCCGTTPDHIRAIAESVR 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10621	NP_001286071.1	mmuM	5..323	CDD:181899	90/365 (25%)
mtr	NP_932338.1	metH	13..1259	CDD:236539	90/365 (25%)
		MetH1	19..337	CDD:223719	89/363 (25%)
		MeTr	369..625	CDD:238381
		methionine_synthase_B12_BD	669..895	CDD:239020
		Met_synt_B12	963..1243	CDD:281030
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920