DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10621 and CG10623

DIOPT Version :9

Sequence 1:	NP_001286071.1	Gene:	CG10621 / 35152	FlyBaseID:	FBgn0032726	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001286073.1	Gene:	CG10623 / 35153	FlyBaseID:	FBgn0032727	Length:	331	Species:	Drosophila melanogaster

Alignment Length:	322	Identity:	173/322 - (53%)
Similarity:	233/322 - (72%)	Gaps:	9/322 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VLVKDGGFGTQMTVHVGDSVDGDPLWSARFNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGY 70
            :|||.|||.:|:..:|.:.|||||||.:||:||||.|:|.||||||:|||||||||||||||:|:
  Fly    14 ILVKCGGFSSQLAKNVTEKVDGDPLWGSRFDATNPEAVIQTHLDFLRNGADIILTNTYQSSVEGF 78

  Fly    71 MEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYT 135
            ::||.:..|:.:|||:.:|:||..|||:||:|...   ..:...|||:.||||:||:||||||||
  Fly    79 VKYLGVTRERGVELIQKSVQLAKQAKEQYLSEIGS---EAESALPLIMGSIGPYGAYLHDGSEYT 140

  Fly   136 GSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCK 200
            |:|||.:..:|:..||:.|||.||.||||.||:||:||.|||||:.|::.|::||.||||:.||.
  Fly   141 GNYADKMSKEELRAWHKTRIEICLAAGVDGLALETLPCLMEAEAVTELVLDNFPDAKFWVSLQCM 205

  Fly   201 DENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVG-EQIPLV 264
            ||..:|.||.||:||.::|.|:..|.|:::.|.||:|||:|.|||||..||.  :..| ::||||
  Fly   206 DEKHMASGENFAEAALSLWRLVQSRKAENRLLGIGLNCVNPLFVTPLLSSLT--KVAGSDRIPLV 268

  Fly   265 VYPNSGEVYDVVNG-WQGREHCVPLANYVPEWAQLGAKVIGGCCRTYARDIRHIGEAIRDWN 325
            ||.|.||:|||..| |.|...  .:..:||||.|||.:::|||||.|..|:..|.:.:...|
  Fly   269 VYSNRGEIYDVEQGDWTGTGE--EVVKFVPEWIQLGVRIVGGCCRVYPTDVLAIRKYVDGLN 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10621	NP_001286071.1	mmuM	5..323	CDD:181899	172/318 (54%)
CG10623	NP_001286073.1	S-methyl_trans	9..322	CDD:304616	172/314 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466215
Domainoid	1	1.000	195	1.000	Domainoid score	I909
eggNOG	1	0.900	-	-		E1_COG0646
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	198	1.000	Inparanoid score	I1324
Isobase	1	0.950	-	0	Normalized mean entropy	S12209
OMA	1	1.010	-	-		QHG62632
OrthoDB	1	1.010	-	-		D39760at7147
OrthoFinder	1	1.000	-	-		FOG0002464
OrthoInspector	1	1.000	-	-		otm26420
orthoMCL	1	0.900	-	-		OOG6_102920
Panther	1	1.100	-	-	P	PTHR46015
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2187
SonicParanoid	1	1.000	-	-		X3176
	14	13.790