DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10621 and zgc:172121

DIOPT Version :9

Sequence 1:	NP_001286071.1	Gene:	CG10621 / 35152	FlyBaseID:	FBgn0032726	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_001108386.1	Gene:	zgc:172121 / 337599	ZFINID:	ZDB-GENE-030131-9545	Length:	311	Species:	Danio rerio

Alignment Length:	310	Identity:	126/310 - (40%)
Similarity:	188/310 - (60%)	Gaps:	16/310 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 VKDGGFGTQMTVHVGDSVDGDPLWSARFNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGYME 72
            :.|||..|::... |..:.||||||||...|:|.||...|..:||:|:|:|.|.|||:|::|:::
Zfish    11 ILDGGLATELEAS-GFLLQGDPLWSARVLHTDPQAIKDVHYRYLQSGSDVITTATYQASIEGFVK 74

  Fly    73 YLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYTGS 137
            ||.:..|::..::.:.|:||......:::   |:.:| ....||:..|:||:|:.|||||||||:
Zfish    75 YLGVQPEEAQHMMMSAVQLAKETVSEFIS---QSPMS-DRREPLVAGSVGPYGSFLHDGSEYTGA 135

  Fly   138 YADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCDDYPDVKFWVAFQCKDE 202
            |.|.:..:|:.||||.:|:..::||.|.:|:||||...|||||||:| .::|:.|.|::|.|||.
Zfish   136 YEDKMTVEELKDWHRPQIQCLVKAGADLVAMETIPGLKEAEALVEVL-KEFPETKAWLSFSCKDN 199

  Fly   203 NTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKFVTPLFKSLNGDREVGEQIPLVVYP 267
            |:::.|..|::|..     :|.|:.|  .:|:||||.....|.||.:|....:..  .:..||||
Zfish   200 NSISSGRRFSEAVE-----MACRSTQ--LVAVGVNCCPAPLVKPLLESAKSHKRA--DLSWVVYP 255

  Fly   268 NSGEVYDVVNGWQGREHCVPLANYVPEWAQLGAKVIGGCCRTYARDIRHI 317
            ||||.:||..||: .|.....||...||...||..||||||....||..:
Zfish   256 NSGEGWDVTTGWK-TEMRTSFANLSLEWKAQGALWIGGCCRVRPADITEL 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10621	NP_001286071.1	mmuM	5..323	CDD:181899	126/310 (41%)
zgc:172121	NP_001108386.1	mmuM	6..306	CDD:181899	126/310 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592702
Domainoid	1	1.000	234	1.000	Domainoid score	I2320
eggNOG	1	0.900	-	-		E1_COG0646
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H101205
Inparanoid	1	1.050	236	1.000	Inparanoid score	I3359
OMA	1	1.010	-	-		QHG62632
OrthoDB	1	1.010	-	-		D518534at33208
OrthoFinder	1	1.000	-	-		FOG0002464
OrthoInspector	1	1.000	-	-		otm26420
orthoMCL	1	0.900	-	-		OOG6_102920
Panther	1	1.100	-	-	LDO	PTHR46015
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2187
SonicParanoid	1	1.000	-	-		X3176
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	15	14.840