Protein Alignment CG10621 and BHMT2

DIOPT Version :9

• Sequence 1: NP_001286071.1
• Gene: CG10621 / 35152
• FlyBaseID: FBgn0032726
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_060084.2
• Gene: BHMT2 / 23743
• HGNCID: 1048
• Length: 363
• Species: Homo sapiens
• Alignment Length: 346
• Identity: 79/346 - (22%)
• Similarity: 120/346 - (34%)
• Gaps: 92/346 - (26%)

  Fly     6 VLVKDGGFGTQMTVHVGDSVDGDPLWSARFNATNPAAIISTHLDFLQNGADIILTNTYQSSVDGY 70
            |::.||.|  .:|:.....|... ||:......:|.|:...|::||:.|::::.|.|:.:|
Human    22 VVIGDGSF--LITLEKRGYVKAG-LWTPEAVIEHPDAVRQLHMEFLRAGSNVMQTFTFSAS---- 79

  Fly    71 MEYLELDEEQSIELIKNTVRLAHIAKERYLTECYQAQLSVQEGYPLIIASIGPFGAHLHDGSEYT 135
                    |.::|.....|..|         .|..|:....:|..|:...|.....:.:...|
Human    80 --------EDNMESKWEDVNAA---------ACDLAREVAGKGDALVAGGICQTSIYKYQKDE-- 125

  Fly   136 GSYADFVPAKEITDWHRVRIEACLEAGVDALAIETIPCQMEAEALVEMLCD-DYPDVKFWVAF-Q 198
                     ..|....|.::|......||.|..|......||...||:|.: |.|     ||. .
Human   126 ---------ARIKKLFRQQLEVFAWKNVDFLIAEYFEHVEEAVWAVEVLKESDRP-----VAVTM 176

  Fly   199 C----KDENTLAHGETFADAANAIWDLLAERNAQDKCLAIGVNCVHPKF-------VTPLFKSLN 252
            |    .|.:.:..||            .|.|..:.....:||||   :|       ...|.|  .
Human   177 CIGPEGDMHDITPGE------------CAVRLVKAGASIVGVNC---RFGPDTSLKTMELMK--E 224

  Fly   253 GDREVGEQIPLVVYPNSGEVYDVVNGWQGREHCVPLANY-------------VPEWAQ----LGA 300
            |....|.:..|:|.|......|.     |:|..|.|..|             :.::|:    ||.
Human   225 GLEWAGLKAHLMVQPLGFHAPDC-----GKEGFVDLPEYPFGLESRVATRWDIQKYAREAYNLGV 284

  Fly   301 KVIGGCCRTYARDIRHIGEAI 321
            :.|||||......||.|.|.:
Human   285 RYIGGCCGFEPYHIRAIAEEL 305

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10621	NP_001286071.1	mmuM	5..323	CDD:181899	79/346 (23%)
BHMT2	NP_060084.2	S-methyl_trans	23..303	CDD:308273	77/341 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0646
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	52	1.000	Inparanoid score	I5453
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D518534at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.870