DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and ERG6

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_013706.1	Gene:	ERG6 / 855003	SGDID:	S000004467	Length:	383	Species:	Saccharomyces cerevisiae

Alignment Length:	206	Identity:	39/206 - (18%)
Similarity:	71/206 - (34%)	Gaps:	64/206 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   307 KPRNRIYTSQLELEAALSK--LSSLQLQFNSDSEHTYGQQLIDWEQIEPTHAKSSALPKERLERK 369
            :.|...:|.:|..:....|  ||:|..:.||..:....:.|.:|:......|:     :.|||..
Yeast     7 RKRQAQFTRELHGDDIGKKTGLSALMSKNNSAQKEAVQKYLRNWDGRTDKDAE-----ERRLEDY 66

  Fly   370 RQQLENLANAV------------------------VSLA------------QPGDRIVDFCSGTG 398
            .:...:..|.|                        .|:|            |.||.::|...|.|
Yeast    67 NEATHSYYNVVTDFYEYGWGSSFHFSRFYKGESFAASIARHEHYLAYKAGIQRGDLVLDVGCGVG 131

  Fly   399 HLAILLALKLPNCTIIVMENKAFSLLQAQKRSNELGLTNCVFYQCNIDYFVGGF----------- 452
            ..|..:| :...|.:|.:.|..:.:.:|:..:.:..|::      .:|:..|.|
Yeast   132 GPAREIA-RFTGCNVIGLNNNDYQIAKAKYYAKKYNLSD------QMDFVKGDFMKMDFEENTFD 189

  Fly   453 ---KIGASLHA 460
               .|.|:.||
Yeast   190 KVYAIEATCHA 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	24/143 (17%)
ERG6	NP_013706.1	Cfa	66..>277	CDD:225139	24/142 (17%)
		Methyltransf_11	124..222	CDD:400514	17/84 (20%)
		Sterol_MT_C	306..368	CDD:400686
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900