DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and Ndufaf5

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_081369.2	Gene:	Ndufaf5 / 69487	MGIID:	1916737	Length:	343	Species:	Mus musculus

Alignment Length:	238	Identity:	49/238 - (20%)
Similarity:	78/238 - (32%)	Gaps:	82/238 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   347 DWEQIEPTHAKSSALPKERLERKRQQLENLANAVVSLAQPGDRIVDFCSGTGHLAILL------- 404
            :|...:|...|...|.:|...|       :|:.|..:|:.....:|...|.|::|..|
Mouse    57 NWAARQPDPMKFDYLKEEVGSR-------IADRVYDIARDFPLALDIGCGRGYIAQHLDKETVGK 114

  Fly   405 ---------ALK------LPNCTIIVMENKAFSLLQAQKRSNELGLTNCVFYQCN--------ID 446
                     |||      :|...|:..|    ..|..|:.:.:|.:::...:..|        |.
Mouse   115 IFQTDIAEHALKNSLETDIPTVNILADE----EFLPFQENTFDLVVSSLSLHWVNDLPRALEQIH 175

  Fly   447 Y-------FVGGFKIGASLH--ACGTATDIVLQQCRRAKAHFVCCPCCYGSLQPMPHIS------ 496
            |       |||....|.:|:  .|    .:.|.:..|.           |...  ||||
Mouse   176 YVLKPDGVFVGAMFGGDTLYELRC----SLQLAETERE-----------GGFS--PHISPFTAVN 223

  Fly   497 ---YPLSKAFQKVL--DTKD----YLYIAHSADQAHEMGTTNC 530
               :.|.:|....|  ||.:    |..:....:....||.:||
Mouse   224 DLGHLLGRAGFNTLTVDTDEIQVNYPGMFELMEDLKGMGESNC 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	29/156 (19%)
Ndufaf5	NP_081369.2	BioC	93..310	CDD:273953	40/195 (21%)
Ndufaf5	NP_081369.2	Methyltransf_11	94..185	CDD:285453	17/94 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900