DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and Alkbh8

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_006509942.1	Gene:	Alkbh8 / 67667	MGIID:	1914917	Length:	709	Species:	Mus musculus

Alignment Length:	382	Identity:	70/382 - (18%)
Similarity:	128/382 - (33%)	Gaps:	131/382 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 KVKRRERVQIKCTTPKEELLIEHRFAEGISFTIADIIL----------YPLLRIVFQHCGQ---- 246
            |:.:.|:..::..:....:|::|...:.:|:....:::          ...|.:..:.||.
Mouse    55 KLTKMEKKFLRKQSKARHVLLKHEGIQAVSYPTQSLVIANGGLGNGVSRKQLLLTLEKCGPVEAL 119

  Fly   247 -MLPHFPLTSTWFSE----------------IDSFGDKCARVLRDLYVPQA-------IKTPPGE 287
             |.|:.|.....|..                ||..|.|....|.  :|.:|       ...|||.
Mouse   120 LMPPNKPYAFVIFQTIEESKKAYFTLNGKEIIDDLGQKIFLYLN--FVEKAQWKNMGLEALPPGL 182

  Fly   288 LGIPDCEATSLYKADPKRYKPRNRIYTSQLELEAALSKLSSLQLQFNSDSEHTYGQQLIDWEQIE 352
            |.:.:                   |.:|:.|.:...|      :.:..|:.:...|:.:...:::
Mouse   183 LVVEE-------------------IISSEEEKKLLES------VNWTEDTGNQNFQRSLKHRRVK 222

  Fly   353 ----PTHAKSSALPKER----------------------LERKRQQLENLANAVVSLAQPG---- 387
                ..|.:|:.:.|::                      ::.|..||      .::..:||
Mouse   223 HFGYEFHYESNTVDKDKPLPGGLPEVCSSILEKLLKEGYIKHKPDQL------TINQYEPGHGIP 281

  Fly   388 ----------DRIVDFCSGTGHLAILLALKLP-NCTIIVMENKAFSLLQAQKRSNEL---GLTNC 438
                      |.|:....|:   ||::..|.| ..|:.||..:. |||.....|..|   |:|..
Mouse   282 AHIDTHSAFEDEIISLSLGS---AIVMDFKHPEGVTVQVMLPRR-SLLVMTGESRYLWTHGITPR 342

  Fly   439 VF--YQCNIDYFVGGF---KIG-ASLHACGTATDIVLQQCRRAKAHFVCCPCCYGSL 489
            .|  .|.: :.|.||.   .|| .:|...|..|....::.||     :.|.|.|.|:
Mouse   343 KFDTVQAS-EQFKGGIITSDIGDLTLSKRGMRTSFTFRKVRR-----MPCNCSYSSV 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286	9/60 (15%)
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	36/141 (26%)
Alkbh8	XP_006509942.1	DUF1891	46..82	CDD:117570	4/26 (15%)
		RRM_ALKBH8	87..167	CDD:240877	13/81 (16%)
		2OG-FeII_Oxy	197..379	CDD:389772	38/198 (19%)
		Methyltransf_25	455..542	CDD:379312
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900