DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and ANTKMT

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_076422.1	Gene:	ANTKMT / 65990	HGNCID:	14152	Length:	235	Species:	Homo sapiens

Alignment Length:	125	Identity:	32/125 - (25%)
Similarity:	43/125 - (34%)	Gaps:	40/125 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   349 EQIEPTHAKSSALPKERLERKRQQLENLANAVVS----------LAQPGDRIVDFCSGTGHLAIL 403
            ||.:|..|.:     |..||:...||.|..|..|          |.|||.|.|.
Human     2 EQDDPVEALT-----ELRERRLGALELLQAAAGSGLAAYAVWALLLQPGFRRVP----------- 50

  Fly   404 LALKLPNCTIIVME-NKAFSLLQAQKRSNELGLTNCVFYQCNIDYFVGGFKIGASLHACG 462
            |.|::|.......: ....|||:.:.     |.|        :|...|..:|..:.|.||
Human    51 LRLQVPYVGASARQVEHVLSLLRGRP-----GKT--------VDLGSGDGRIVLAAHRCG 97

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	26/106 (25%)
ANTKMT	NP_076422.1	N-terminal sequence (NTS). /evidence=ECO:0000303\|PubMed:31213526	1..22		7/24 (29%)
		Methyltransferase (MTase). /evidence=ECO:0000303\|PubMed:31213526	43..77		11/49 (22%)
		Pre-methyltransferase (preMT). /evidence=ECO:0000303\|PubMed:31213526	43..77		11/49 (22%)
		HemK	<65..>123	CDD:225443	11/46 (24%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	215..235
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900