DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and Alkbh8

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001178838.1	Gene:	Alkbh8 / 366783	RGDID:	1304687	Length:	664	Species:	Rattus norvegicus

Alignment Length:	436	Identity:	69/436 - (15%)
Similarity:	143/436 - (32%)	Gaps:	151/436 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 KVKRRERVQIKCTTPKEELLIEHRFAEGISFTIADIIL----------YPLLRIVFQHCGQ---- 246
            |:.:.|:..::..:....:|::|...:.:|:....:::          ...|.:..:.||.
  Rat    10 KLTKMEKKFLRKQSKARHVLLKHEGIQAVSYPTQSLVIANGGLGNAVSRKQLLLTLEKCGPVEAL 74

  Fly   247 -MLPHFPLTSTWFSE----------------IDSFGDKCARVLRDLYVPQAIK-----TPPGELG 289
             |.|:.|.....|..                ||..|.|....|..:...|..|     .|||.|.
  Rat    75 LMPPNKPYAFVIFQTIEESKKAYSILNGKEIIDDLGQKIFLYLNFVEKAQWKKLGLQALPPGLLV 139

  Fly   290 IPDCEATSLYKADPKRYKPRNRIYTSQLELEAALSKLSSLQLQFNSDSEHTYGQQLIDWEQIE-- 352
            :.:                   |.:|:.|      |:....:.:..|:.:.:.|:.:...:::
  Rat   140 VEE-------------------IISSEEE------KMLLESVNWTEDTGNQHFQRSLKHRRVKHF 179

  Fly   353 --PTHAKSSALPKER----------------------LERKRQQL------------------EN 375
              ..|.:::.:.|::                      ::.|..||                  ..
  Rat   180 GYEFHYENNTVDKDKPLPGGLPEICSSILEKLLKEGYIKHKPDQLTINQYEPGHGIPAHIDSHSA 244

  Fly   376 LANAVVSLAQPGDRIVDFCSGTGHLAILLALKLPNCTIIVMENKA------------FSLLQAQK 428
            ..:.:|||:.....::||....|   :.:.:.||..:::||..::            |..:||.:
  Rat   245 FEHEIVSLSLGSAIVMDFKHPEG---VTVQVMLPRRSLLVMTGESRYLWTHGITPRKFDTIQASE 306

  Fly   429 RSNELGLTNCVFYQCNIDYFVGGF---KIG-ASLHACGTATDIVLQQCRRAKAHFVCCPCCYGSL 489
            :                  |.||.   .|| .:|...|..|....::.||     :.|.|.|.|:
  Rat   307 Q------------------FKGGIINSDIGDLTLSKRGMRTSFTFRKVRR-----IPCNCSYSSV 348

  Fly   490 QPMPHISYP--LSKAFQKVLDTKDYLYIAHSADQ-AHEMGTTNCKP 532
            ......:.|  |.::.::.|:. :..::.|..|: |....:|...|
  Rat   349 CDRQRKATPPSLLESSKEALEL-EQKHVHHVYDEIASHFSSTRHSP 393

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286	9/60 (15%)
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	28/151 (19%)
Alkbh8	NP_001178838.1	DUF1891	1..37	CDD:117570	4/26 (15%)
		RRM_ALKBH8	42..122	CDD:240877	12/79 (15%)
		2OG-FeII_Oxy	152..334	CDD:304390	28/202 (14%)
		Methyltransf_11	412..501	CDD:285453
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900