DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and Prmt2

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001289894.1	Gene:	Prmt2 / 15468	MGIID:	1316652	Length:	475	Species:	Mus musculus

Alignment Length:	222	Identity:	45/222 - (20%)
Similarity:	80/222 - (36%)	Gaps:	78/222 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 QLYLEIEISTQKETTIYTGV-------------------SSFLALFTYKFLKDPKNVRVNFVSTK 48
            :|:||: ::.|..||.|..|                   :..::||.....: ||.|..
Mouse   122 KLHLEM-LADQPRTTKYHSVILQNKESLKDKVILDVGCGTGIISLFCAHHAR-PKAVYA------ 178

  Fly    49 IEGGKIALRSSQ--LKKELTDRHITCRDAASLPAIQDLKLPIYEKDGNTFIA---GTCAVCRELI 108
            :|...:|..:||  |:....|.....:.     .::|:.||  || .:..::   |||.:...:|
Mouse   179 VEASDMAQHTSQLVLQNGFADTITVFQQ-----KVEDVVLP--EK-VDVLVSEWMGTCLLFEFMI 235

  Fly   109 -----ARQPNEELKKLLGFKGSCLLAPSEASI-----------------WTKFCEVDLVAVVSKL 151
                 ||.        ...||..::.|:.|::                 |....|.:|    |.|
Mouse   236 ESILYARD--------TWLKGDGIIWPTTAALHLVPCSAEKDYHSKVLFWDNAYEFNL----SAL 288

  Fly   152 HSGQVLEFVPQ----EVVRFEQHMNEP 174
            .|..:.||..:    .:::.|..::||
Mouse   289 KSLAIKEFFSRPKSNHILKPEDCLSEP 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624
Prmt2	NP_001289894.1	SH3_PRMT2	46..98	CDD:212740
		AdoMet_MTases	122..>181	CDD:302624	13/66 (20%)
		AdoMet_MTases	153..253	CDD:100107	24/122 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900