DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10428 and BUD23

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	XP_006715910.1	Gene:	BUD23 / 114049	HGNCID:	16405	Length:	304	Species:	Homo sapiens

Alignment Length:	158	Identity:	31/158 - (19%)
Similarity:	47/158 - (29%)	Gaps:	66/158 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 QAIKTPPGELGIPDCEATS----LYKADPKRYKPRNRIYTSQLELEAALSKLSSLQLQ-FNSDSE 338
            |.|...||.  ...|.:.|    |..|:.|...|..|:|.....|.:.|.:.|...|| :..:||
Human   130 QGIPFKPGT--FDGCISISAVQWLCNANKKSENPAKRLYCFFASLFSVLVRGSRAVLQLYPENSE 192

  Fly   339 HT------------YGQQLIDW-----------------------------EQIEPTHA------ 356
            ..            .|..::|:                             :::||..:
Human   193 QLELITTQATKAGFSGGMVVDYPNSAKAKKFYLCLFSGPSTFIPEGLSENQDEVEPRESVFTNER 257

  Fly   357 ------------KSSALPKERLERKRQQ 372
                        ||.|...|:.||.|:|
Human   258 FPLRMSRRGMVRKSRAWVLEKKERHRRQ 285

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	3/5 (60%)
BUD23	XP_006715910.1	AdoMet_MTases	38..>117	CDD:302624
		Methyltransf_11	81..184	CDD:285453	15/55 (27%)
		WBS_methylT	227..302	CDD:289366	10/59 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900