DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10428 and Prmt9

DIOPT Version :9

Sequence 1:	NP_609918.1	Gene:	CG10428 / 35150	FlyBaseID:	FBgn0032724	Length:	585	Species:	Drosophila melanogaster
Sequence 2:	NP_001074709.1	Gene:	Prmt9 / 102182	MGIID:	2142651	Length:	846	Species:	Mus musculus

Alignment Length:	480	Identity:	86/480 - (17%)
Similarity:	150/480 - (31%)	Gaps:	180/480 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   188 ANQTENGGKVKRRERVQIKCTTPKE-----ELLIEHR-----FAEGISFTI----ADIILYPLLR 238
            ||:.|||.|:...:.:.|:  .||.     .|::...     |.|||..::    ..::|.|..:
Mouse   222 ANKMENGIKLLHMKSLDIE--IPKHIPERVSLVVTETVDAGVFGEGIVESLIHAWEHLLLQPKTK 284

  Fly   239 IVFQHCGQMLPHFPLTSTWFSEIDSFGDKCARVLR----------DLYVPQAIK-TPPGELGIPD 292
            ....:||:.....|..:..|    ....:||.:.|          .:::|..:| ..|....:..
Mouse   285 EENGNCGKYGKVIPAGAVIF----GMAVECAEIRRHHRVGAKDIAGIHLPTNVKFQSPAYTSVDT 345

  Fly   293 CEATSLYKAD-----PKRYKPRNRI-------YTSQLELEAALSK--------------LSSLQL 331
            .|....|..:     |..|.|....       :.:..||::..:|              |.::.:
Mouse   346 EETVEPYTTEKMSGIPGGYLPLTECFQIMKVDFNNLQELKSLATKKPHSLNVPAIKEGVLDAIMV 410

  Fly   332 QF-----------NSDSEHTYGQQLIDWEQ-IEPTHAKSSALPKERLERKRQQLENLANAVVSLA 384
            .|           .|.||.|.      ||| :.|.                |.||:..      .
Mouse   411 WFVLQLDDEYSLSTSPSEETC------WEQAVYPV----------------QALEDYC------I 447

  Fly   385 QPGDRIVDFCSGTGHLAILLALKLPNCTIIVMENKAFSLLQAQKRSNELGLTNCVFYQCNIDYFV 449
            |||||:.  ...:.|...   |::...:|:.:|:: ..:::...:|.:|
Mouse   448 QPGDRVT--MEASCHDCY---LRIQGISILHLEHE-MEVMKGFTKSKDL---------------- 490

  Fly   450 GGFKIGASLHACGTATDIVLQQCRRAKAHFVCCPCCYGSLQP-----MPHISY--PLSKAFQKVL 507
              ..:|.....|....::   |..|.:|....|     .|:|     :.:|.|  ....|.:|||
Mouse   491 --LSLGNEAELCSALANL---QTSRPEALEQTC-----MLEPTEIALLNNIPYHEGFKTAMRKVL 545

  Fly   508 DTKDYLYIAHSADQAHEMGTTNCKPETTLQGL--HCM---------------SVVDTDRLLQAEE 555
                                ::..||...|.:  ||.               |..|...:|...|
Mouse   546 --------------------SSLAPELLWQPMDTHCQYMEMNSGSGQSDAAPSTADPFYVLDVSE 590

  Fly   556 AGYQVI------LTRLKPEQCTPKN 574
             |:.::      |..:||.....|:
Mouse   591 -GFSLLPILAGTLGHVKPYSSVEKD 614

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10428	NP_609918.1	GST_C_family	<212..258	CDD:198286	10/59 (17%)
CG10428	NP_609918.1	AdoMet_MTases	368..486	CDD:302624	20/117 (17%)
Prmt9	NP_001074709.1	TPR 1	25..58
		TPR 2	67..100
		TPR_11	68..132	CDD:290150
		TPR repeat	68..95	CDD:276809
		TPR repeat	100..130	CDD:276809
		TPR 3	101..134
		AdoMet_MTases	148..>303	CDD:302624	19/82 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900