Protein Alignment ssp3 and Scaper

DIOPT Version :9

• Sequence 1: NP_609917.2
• Gene: ssp3 / 35149
• FlyBaseID: FBgn0032723
• Length: 1732
• Species: Drosophila melanogaster
• Sequence 2: NP_001074810.1
• Gene: Scaper / 244891
• MGIID: 1925976
• Length: 1398
• Species: Mus musculus
• Alignment Length: 1857
• Identity: 415/1857 - (22%)
• Similarity: 667/1857 - (35%)
• Gaps: 671/1857 - (36%)

  Fly     2 EMREVLSREGREAKNLLVYQFCDETTSSGATSGFGSTGGDVGGGSGGDGPAVGSGGVLLNGDCYR 66
            ::|.:::.|||.|:||:.:.
Mouse    13 KVRRIVAEEGRTARNLIAWS--------------------------------------------- 32

  Fly    67 KPPMVP--PKSPNGTPKNCQS---------PTSPRLKSSASVGCGGGSSGGPRVRSAS---TGRD 117
                ||  .|..:|.|| ||:         .|....|.:.:|.|...|:.|.:....|   |...
Mouse    33 ----VPLESKDDDGKPK-CQTGGKSKRTIQGTHKTTKQNTAVECKITSTTGEKHFDKSPTKTRHP 92

  Fly   118 KKSELQARYWALLFGNLQRAINEIYQTVECYENISSCQETILVLENYVRDFKALCEWFKVSWDYE 182
            :|.:|:|||||.||.||:||::|||.|.|..:::..|:|.:::|:.||||||||.:|.::....|
Mouse    93 RKIDLRARYWAFLFDNLRRAVDEIYVTCESDQSVVECKEVLMMLDYYVRDFKALIDWIQLQEKLE 157

  Fly   183 SRPLQQRPQSLAWEVRKSNPTPRVRTRSLCSPNNSGKSSPALFPGTQSGETSPFCDNGQISPRKL 247
            ....|.||.||||||:|.:|...|                     .||..|.
Mouse   158 KTDAQSRPTSLAWEVKKMSPGRHV---------------------IQSPSTD------------- 188

  Fly   248 LRAYDQVPKGAMRLNVRELFAASKRATQGSSQSDNMEGPLDLSGDKSNFVLRSTQYAQTDLEDPH 312
                        |:||
Mouse   189 ------------RMNV------------------------------------------------- 192

  Fly   313 LTLADVREKMRMEAEEREAQNRIENEALEEVTIPIDNEDATESLNKQEPSSLELPIHNVADLSKE 377
                                                ...|..|||
Mouse   193 ------------------------------------TSTARRSLN-------------------- 201

  Fly   378 PELMEAASEATALEMTVASLESMENALLNQQANKEPTPPSTVIKPLAEILKKPQPLNPLSGNNVQ 442
                                                                             
Mouse   202 ----------------------------------------------------------------- 201

  Fly   443 NSPLKYSSVLNRPSKKMIPPPGGVAAQKTISTKPGLVKPNLTTTVNGLRSTKTATAPPAIKTTGR 507
                 :.|:           ||.|.|                               |.:..||.
Mouse   202 -----FGSL-----------PGAVTA-------------------------------PCLAPTGV 219

  Fly   508 SGLQRHPRPSSKTECYGPPNNVASRLSARSRTMLEINGRNTNSSARTLPKKTNPGSILSTATRTK 572
            |...:                              :...:|.|:    |.:..|....:..|..|
Mouse   220 SWADK------------------------------VKAHHTGSA----PPEATPAQSCAPMTVQK 250

  Fly   573 MSSRLSSREDITSSTSTLKASNEQLSNSRNTLKAENQHSEPKQIQPPTDADDGWLTVKNRRRTSM 637
             :||.:.|:|.                                        :||.||:..|..
Mouse   251 -TSRKNERKDA----------------------------------------EGWETVQRGRPV-- 272

  Fly   638 HWANRFNQPTGYASLPTLALLNEQQKEQEHKEKQKGEDDGKVIVKTISAKTKAPIEVAKAKAKTS 702
                   :....|.:|.::|:.|..:.::..:|:.
Mouse   273 -------RSRSTAVIPKVSLVTETLRSKDDSDKEN------------------------------ 300

  Fly   703 IVITRPEIKNAKAKVNSFPVQKSNTNQVKKPEKQEKSDTTAPAAIASSSNTRNSSHSICVGRNSI 767
             :...||                  ..::|.:.:::..|.  .:::..|...:|.|.:
Mouse   301 -ICLLPE------------------ESIQKGKLEDRCSTV--ESLSKDSLLHSSDHPL------- 337

  Fly   768 IKRQKSDLTGLKMTSLHKEYMRSEKNALRKLQQKEQGNQQHNSSSSSAETVVESCNEDHSKIDIK 832
                 |:.|...:..|.              ..|..|:.|.:|..:|....::|   |...:..:
Mouse   338 -----SERTQFTVCILD--------------DVKNSGSSQDSSVHTSEIPAIDS---DAVCVAPQ 380

  Fly   833 IQTNCEFSKTIGELYESIAHCKLPSGSLKTNASTLSACD-------ENEEQNTDDNEEERNERIL 890
            ..|.....:...|....:.....||     :.|.:||.|       ..:|:..|..|:...|.|.
Mouse   381 NTTALPTDRVPAETTGMVTEMTDPS-----DISNVSAADWSMAEVLAKKEELADRLEKANEEAIA 440

  Fly   891 GEV--QESLERQIRELEQTEIDVDTETDETDCEVQLEEQDDGVDGLEMGSGDDSAVFVTMS-DDE 952
            ..:  :|.|.|:|...|..:|:::|:.| :|...            .||||..|...|::. :|.
Mouse   441 SAIAEEEQLTREIEAEENNDINIETDND-SDFSA------------SMGSGSLSFCGVSLDWNDV 492

  Fly   953 NASLELRYQALLSDMSWNERAEALATLQAYVARHPGRAQELHQKLSSPSRRRSLQETLKKYQAKQ 1017
            .|..|.| ::...:.||.:      .::...||.||....:|:|||||||:|::.|:.|||:.|.
Mouse   493 LADYEAR-ESWRQNTSWGD------IVEEEPARLPGHGIHMHEKLSSPSRKRTIAESKKKYEEKH 550

  Fly  1018 ARAQQKRNLLQQEKAAKLQQLFSRVEDVKAAKNQIIEDKRQKMQGRLQRAAENREQYLKQIIEKA 1082
            .:|||.|..|::||..|||:|..|.:||:..|.::::.:|:.|:.:|..|...||..|:.|::||
Mouse   551 MKAQQLREKLREEKTLKLQKLLEREKDVRKWKEELLDQRRRMMEEKLLHAEFKREVQLQAIVKKA 615

  Fly  1083 HDEEKKLKEINFIKNIEAQNKRLDLLESSKETEGRLQDLEQERQKRVEEKLAKEAAVERRRQALE 1147
            .:||.|:.||.||..:||||||.|:|...||.|.||.:|::|||:|.|||.|::.||:.|::|||
Mouse   616 QEEEAKVNEIAFINTLEAQNKRHDVLSKLKEYEQRLNELQEERQRRQEEKQARDEAVQERKRALE 680

  Fly  1148 KERLLKLEKMNETRLEKEQRIGKMQEQKEKQRQALAREKARDREERLLALQVQQQQTTEELQRKI 1212
            .||..::|::...|.|:|.||.:.:::|||.|:..|||:||||||||.||...||:..||||:||
Mouse   681 AERQARVEELLMKRKEQEARIEQQRQEKEKAREDAARERARDREERLAALTAAQQEAMEELQKKI 745

  Fly  1213 LQKQMESARRHEENIEHIRQRALELT--------------------------------------- 1238
            ..|..||.|||.|.||..:::|.||:
Mouse   746 QLKHDESIRRHMEQIEQRKEKAAELSSGRHASTDYAPKLTPYERKKQCSLCNVLIASEVYLFSHI 810

  Fly  1239 --------IPTRQADEGR--GDQDVSEDILNGNATSTTNEDCDLSSSLSEVGGNNAHTRSYKKKM 1293
                    :....:.:||  .|::|....|.........|    |::..|...:....:..|||.
Mouse   811 KGKKHQQAVRENSSIQGRELSDEEVEHLSLKKYVVDIVIE----SAAPPEPVKDGEERQKNKKKA 871

  Fly  1294 KKLKQRMNQCAAEYLESLEA------LPAHARRDSTVPKLL-NLVVKGGG------AQGLDRNLG 1345
            ||:|.|||..|.||...:|.      .|..|:.......|: .|.|:..|      |..|||.||
Mouse   872 KKIKARMNIRAKEYENLVETKNSGSESPYKAKLQRLTKDLVKQLQVQDSGSWVNNKASALDRTLG 936

  Fly  1346 NLLRVIPKAQTLDFLAFLCMDGLGILAN--HVISKGMDEN--SEISRKSVYLAAQLYRNACSVCP 1406
            .:.|::.|....|.::|....||..|.|  .|::...:.|  |.|..||:..|..:|..||:.|.
Mouse   937 EIARILEKENVPDQISFQVAGGLTALENILQVVTPATNMNTVSRIPPKSLCNAINVYSLACNNCS 1001

  Fly  1407 QIARHALLGNSITVLFDAI--NKSFQLPEEK--------SPQHPVELSTELMLACTEALSSSYVK 1461
            :.....|..|.||.|.|.:  ..:..:|:|.        :.|....|:|.|:.|.....|.....
Mouse  1002 ENCTDVLFSNKITFLMDLLIHQLTVYVPDENNAVLGRNTNKQVFEGLTTGLLRAGAVVFSCLIAN 1066

  Fly  1462 K---NTHPKVPE------------------RLPDMINYAVITGLIEILSRRIQKVRESIESNKSV 1505
            :   |:.|..|:                  |:.|:|:|.|..|||:.|......|:..::.|..:
Mouse  1067 RPDGNSRPATPKISTQEMKNKPSQGDAFNSRVQDLISYVVNMGLIDRLHGCFLSVQGPVDENPKM 1131

  Fly  1506 MLSLLTTLGFLSRFIDVC-----------QPGPADPTRLLSAAKSTELFGTVSMLYGCVMPMG-- 1557
            ...|....|||.....:|           .....|||.|.:|.::|:|.|.:.||| |::..|
Mouse  1132 ATFLQHAAGFLRGMCMLCFAVTGRSSSIFDNNHQDPTGLTAALQATDLAGVLHMLY-CILFHGTI 1195

  Fly  1558 --------ECIPPRTTALAASTFHLYVSLASLDVNTFQETLTVEGPLSLKLLDVMTVIL-NCSLV 1613
                    :.....|..:|..:...:.|.|.||::.||..:..|| |||....:.:.:| :||.|
Mouse  1196 SDAGTSPKDSYTQNTIQVAIQSLRFFNSFAILDLSAFQSVVGAEG-LSLAFRHMASSLLGHCSQV 1259

  Fly  1614 NDQWTTNSESCPMLI-DLVASMAFFCVNNRRHQDLLISEQYAVIFKRMAKLPTQF--NP----VI 1671
                     ||..|: :::..:.:|.||:..:|.::.|.::..:.:::.:||.|:  :|    |:
Mouse  1260 ---------SCESLLHEVIVCVGYFTVNHPDNQVIVQSGRHPTVLQKLCQLPFQYFSDPRLIKVL 1315

  Fly  1672 YPFLVTVSFNNPPAREFLSKDFD----LTFLDEYSKS 1704
            :|.|:|...||...:..|.::..    .||:.:::::
Mouse  1316 FPSLITACHNNHQNKLILEQEMSCVLLATFIQDFAQT 1352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssp3	NP_609917.2	SCAPER_N	113..208	CDD:293110	45/97 (46%)
		FAM184	870..1060	CDD:292293	61/199 (31%)
		SPEC	991..1192	CDD:295325	93/200 (47%)
		GBP_C	<1111..1193	CDD:303769	40/81 (49%)
Scaper	NP_001074810.1	SCAPER_N	89..185	CDD:374584	45/116 (39%)
		PTZ00121	<536..910	CDD:173412	134/377 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167845445
Domainoid	1	1.000	96	1.000	Domainoid score	I7371
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	432	1.000	Inparanoid score	I1704
Isobase	1	0.950	-	0	Normalized mean entropy	S8282
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006395
OrthoInspector	1	1.000	-	-		oto94507
orthoMCL	1	0.900	-	-		OOG6_106354
Panther	1	1.100	-	-	LDO	PTHR31434
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3307
SonicParanoid	1	1.000	-	-		X5352
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.960