Protein Alignment ssp3 and scaper

DIOPT Version :9

• Sequence 1: NP_609917.2
• Gene: ssp3 / 35149
• FlyBaseID: FBgn0032723
• Length: 1732
• Species: Drosophila melanogaster
• Sequence 2: XP_005163211.4
• Gene: scaper / 100144551
• ZFINID: ZDB-GENE-060303-5
• Length: 1467
• Species: Danio rerio
• Alignment Length: 1871
• Identity: 418/1871 - (22%)
• Similarity: 671/1871 - (35%)
• Gaps: 683/1871 - (36%)

  Fly     2 EMREVLSREGREAKNLLVYQFCDETTSSGATSGFGSTGGDVGGGSGGDGPAVGSG---------G 57
            ::|::::.|||.|:||:.:....|:....|.|       ...|.|......:.||         |
Zfish    69 KVRKIVAEEGRAARNLIAWSVPVESKEEEAKS-------KSHGNSNARAQRINSGLHRNKKQNSG 126

  Fly    58 VLLNGDCYRKPPMVPPKSPNGTPKNCQSPTSPRLKSSASVGCGGGSSGGPRVRSASTGRDKKSEL 122
            :    ||...|..:..|.|..:|...:.|                               :|.:|
Zfish   127 L----DCKNGPGSILDKGPEKSPTKTRQP-------------------------------RKVDL 156

  Fly   123 QARYWALLFGNLQRAINEIYQTVECYENISSCQETILVLENYVRDFKALCEWFKVSWDYESRPLQ 187
            :|||||.||.||:||::|||.|.|..:::..|:|.:::|:|||||||||.:|.::....|....|
Zfish   157 RARYWAFLFDNLRRAVDEIYVTCESDQSVVECREVLMMLDNYVRDFKALIDWIQLQEKLEKTDAQ 221

  Fly   188 QRPQSLAWEVRKSNPTPRVRTRSLCSPNNSGKSSPALFPGTQSGETSPFCDNGQISPRKLLRAYD 252
            .||.||||||||.:|     .|.:.|..:|.:..|:  ||.                |:.|....
Zfish   222 NRPTSLAWEVRKMSP-----GRHVMSSPSSDRIVPS--PGV----------------RRALNFGG 263

  Fly   253 QVPKGAMRLNVRELFAASKRATQGSSQSDNMEGPLDLSGDKSNFVLRSTQYAQTDLED------- 310
            ..|          ..|.::.:..|.|.:|.::....|.....:..:.:.:.|:.|.|.
Zfish   264 PPP----------TLAVARLSHTGPSWADRVKSSHSLPVPSQSVYIPAEKPAKKDAEGWETVQRG 318

  Fly   311 ----PHLTLADVREKMRMEAEEREAQNRIENEALEEVTIPIDNEDATESLNKQEPSSLELPIHNV 371
                |...::.|    .:.|..::..:: ||:.::.     ..:|.::.:.:|||   .:|....
Zfish   319 RSMRPRAKVSPV----LVHASPKDDSDK-ENQHVQP-----SPQDKSQDVREQEP---PIPQEPS 370

  Fly   372 ADLSKEPELMEAASEATALEMTVASLESMENALLNQQANKEPTPPSTVIKPLAEILKKPQPLNPL 436
            .::.|.|.:...|             ||:|....:..|..|.|||.| ..|      .|.|.:||
Zfish   371 KEMEKTPVIEHPA-------------ESIEEEGQSVSAPSEDTPPLT-SDP------TPPPTSPL 415

  Fly   437 SGNNVQNSPLKYSSVLNRPSKKMIPPPGGVAAQKTISTKPGLVKPNLTTTVNGLRSTKTATAPPA 501
                           |......::|.|                .|:..|.|   :|.:|.|
Zfish   416 ---------------LQVQCPDLVPDP----------------SPHPVTLV---QSEETGT---- 442

  Fly   502 IKTTGRSGLQRHPRPSSKTECYGPPNNVASRLSARSRTMLEINGRNTNSSARTLPKKTNPGSILS 566
                   ||                                           |..::...||:
Zfish   443 -------GL-------------------------------------------TKVEQGTEGSV-- 455

  Fly   567 TATRTKMSSRLSSREDITSSTSTLKASNEQLSNSRNTLKAENQHSEPKQIQPPTDADDGWLTVKN 631
                                                                             
Zfish   456 ----------------------------------------------------------------- 455

  Fly   632 RRRTSMHWANRFNQPTGYASLPTLALLNEQQKEQEHKEKQKGEDDGKVIVKTISAKTKAPIEVAK 696
                   |.                                        |.|.|.|.:||:.|..
Zfish   456 -------WK----------------------------------------VATPSTKAEAPVYVPL 473

  Fly   697 AKAKTSIVITRPEIKNAKAKVNSFPVQKSNTNQVKK--PEKQEKSDTTAPAAIASSSNTRNSSHS 759
            |      |:|...:.:        |.:.|....:.:  .:|:|.:|.
Zfish   474 A------VMTLESLLD--------PTELSTPQSMAEVLAKKEEMADR------------------ 506

  Fly   760 ICVGRNSIIKRQKSDLTGLKMTSLHKEYMRSEKNALRKLQQKEQGNQQHNSSSSSAETVVESCNE 824
                                                                       :|..||
Zfish   507 -----------------------------------------------------------LEKANE 512

  Fly   825 DHSKIDIKIQTNCEFSKTIGELYESIAHCKLPSGSLKTNASTLSACDENEEQNTDDNEEERNERI 889
                                   |:||                ||..|
Zfish   513 -----------------------EAIA----------------SAIAE----------------- 521

  Fly   890 LGEVQESLERQIRELEQTEIDVDTETDETDCEVQLEEQDDGVDGLEMGSGDDSAVFVTMSDDENA 954
                :|.|.|:| :.|.:|::.|.|:|.:               ..:|||             :.
Zfish   522 ----EEQLTREI-QAENSELETDNESDFS---------------ASIGSG-------------SC 553

  Fly   955 SLELRYQALLSDMS----WNERAEALATLQAYVARHPGRAQELHQKLSSPSRRRSLQETLKKYQA 1015
            .|.|.:..:|:|..    |.:.......::...||.||....:|:|||||||:|::.|:.||::.
Zfish   554 GLNLDWSEMLADYEAREPWRQSTSWGDIVEEEPARPPGHGIHMHEKLSSPSRKRTIAESKKKHEE 618

  Fly  1016 KQARAQQKRNLLQQEKAAKLQQLFSRVEDVKAAKNQIIEDKRQKMQGRLQRAAENREQYLKQIIE 1080
            ||.:|||.|:.|::||..|||:|..|.:||:..|.::::.:|:.|:.:|..|...||..|:.|::
Zfish   619 KQLKAQQLRDKLREEKTHKLQKLMEREKDVRKWKEELLDQRRKMMEEKLLHAEFKRELQLQAIVK 683

  Fly  1081 KAHDEEKKLKEINFIKNIEAQNKRLDLLESSKETEGRLQDLEQERQKRVEEKLAKEAAVERRRQA 1145
            ||.:||.|:.||.||..:||||||.|:|....|.|.||.:|::|||:|.|||.|::.||:.|::.
Zfish   684 KAQEEEAKVNEIAFINTLEAQNKRHDVLAKLDEYEQRLNELQEERQRRQEEKQARDEAVQERKRV 748

  Fly  1146 LEKERLLKLEKMNETRLEKEQRIGKMQEQKEKQRQALAREKARDREERLLALQVQQQQTTEELQR 1210
            ||.||..::|::...|.|:|.||.:.:::|::.|:..|||:||||||||.||...||:..||||:
Zfish   749 LEAERQARVEELLMKRREQEARIEQQRQEKDRAREDAARERARDREERLAALSAAQQEAMEELQK 813

  Fly  1211 KILQKQMESARRHEENIEHIRQRALELTIPTRQAD------------------------------ 1245
            ||..|..||:|||.|.:|..:::|.||: ..|.|:
Zfish   814 KIQMKHDESSRRHMEQMEQRKEKAAELS-SGRHANTDYAPKLTPYERKKQCSLCNVVITSEVHLF 877

  Fly  1246 ---EGRGDQDVSEDILNGNATSTTNEDCDLSSSL---------SEVGGNNA----HTRSYKKKMK 1294
               :|:..|....|..:......::|:.:..|..         |.|..:||    ..:..:||.|
Zfish   878 SHIKGKRHQQAVRDSSSIQGRELSDEEVEHLSQKKYIVDIVTDSIVSSDNAKDGEERQKARKKAK 942

  Fly  1295 KLKQRMNQCAAEYLESLEALPAHARRDSTVPKLLNLVVK---------------GGGAQGLDRNL 1344
            ||:.|||..|.||...:||  .....||.....|..:||               .....||||.|
Zfish   943 KLRARMNSRAKEYETCMEA--KSQTSDSPYKAKLQRLVKDLVKQQQGQDSGQWASNKVSGLDRTL 1005

  Fly  1345 GNLLRVIPKAQTLDFLAFLCMDGLGILANHV-ISKGMDENSEISR---KSVYLAAQLYRNACSVC 1405
            |.:.|::.|....|.:||....||..|...: :...:...:.:.|   ||:..|...|..:|:.|
Zfish  1006 GEISRILEKQNNADQVAFQVGGGLSALEQILQVVTAISSPTAVPRIPLKSLCAAVNTYYLSCTHC 1070

  Fly  1406 PQIARHALLGNSITVLFDAINKSFQL---PEEKS---------------------------PQHP 1440
            .....:.|..|.||.|.|.:.....|   .|:||                           ..:|
Zfish  1071 HNNCAYVLYSNKITFLMDLLLHQLTLFVPDEDKSIFGRSVNKQVFEGLTTGLLQTVATVLGQLYP 1135

  Fly  1441 VELSTELMLACTEALSSSYVKKNTHPKVPE----RLPDMINYAVITGLIEILSRRIQKVRESIES 1501
            ..|..:....||..:.|.       |...|    |..|:|:|.|..|||:.|......::..|:.
Zfish  1136 TNLDGDAPRICTPDIKSK-------PAASENFNTRAQDLISYVVNVGLIDKLYGCFLSIQGPIDE 1193

  Fly  1502 NKSVMLSLLTTLGFL-----------SRFIDVCQPGPADPTRLLSAAKSTELFGTVSMLYGCVM- 1554
            :..:...|.....||           .|.:.|......|||.|.:..:||:|.|.:.||| |::
Zfish  1194 SPKMAAFLEQATAFLHGLCKLCFAVTGRSLSVFDNKRQDPTGLTALLQSTDLVGVLHMLY-CILL 1257

  Fly  1555 -----------PMGECIPPRTTALAA--------STFHLYVSLASLDVNTFQETLTVEGPLSLKL 1600
                       |.|...|...|.:..        :||.|      ||::.||..|..|| |||..
Zfish  1258 HSAPPEPLSGGPAGPQGPYSATVIQVALQGLRFLNTFSL------LDLSAFQGVLGAEG-LSLAF 1315

  Fly  1601 LDVMTVILNCSLVNDQWTTNSESC-PMLIDLVASMAFFCVNNRRHQDLLISEQYAVIFKRMAKLP 1664
            ..:::.:|        |..:.:|. .:|.:|:..:.:|.||:..:|.::.|.:...:.:::.:||
Zfish  1316 RHIVSSLL--------WFCSQQSSEDLLHELIICVGYFTVNHPDNQVIVQSGRQPSVLQKLCQLP 1372

  Fly  1665 TQF--NP----VIYPFLVTVSFNNPPAREFLSKDFD----LTFLDEYSKSE 1705
            .|:  :|    |::|.|:...:||...:..|.::..    .||:.:.:.:|
Zfish  1373 FQYFSHPRLIKVLFPSLICACYNNLQNKVILQQEMSCVLLATFIQDCATNE 1423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ssp3	NP_609917.2	SCAPER_N	113..208	CDD:293110	44/94 (47%)
		FAM184	870..1060	CDD:292293	52/193 (27%)
		SPEC	991..1192	CDD:295325	89/200 (45%)
		GBP_C	<1111..1193	CDD:303769	36/81 (44%)
scaper	XP_005163211.4	SCAPER_N	147..242	CDD:293110	46/130 (35%)
		Neuromodulin_N	<494..839	CDD:331332	145/510 (28%)
		ZnF_U1	859..890	CDD:197732	2/30 (7%)
		C2H2 Zn finger	863..885	CDD:275371	1/21 (5%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590014
Domainoid	1	1.000	101	1.000	Domainoid score	I6926
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	414	1.000	Inparanoid score	I1805
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D51626at33208
OrthoFinder	1	1.000	-	-		FOG0006395
OrthoInspector	1	1.000	-	-		oto41330
orthoMCL	1	0.900	-	-		OOG6_106354
Panther	1	1.100	-	-	LDO	PTHR31434
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3307
SonicParanoid	1	1.000	-	-		X5352
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	11.020