Protein Alignment tup and lmx1ba

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001349521.1
• Gene: lmx1ba / 554361
• ZFINID: ZDB-GENE-050114-3
• Length: 375
• Species: Danio rerio
• Alignment Length: 469
• Identity: 128/469 - (27%)
• Similarity: 192/469 - (40%)
• Gaps: 128/469 - (27%)

  Fly    23 QTGLQPSLVMNHHLDLDCHGHDVIKKQRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQ 87
            :||.:...||   |..||..|.       |.|.||...|.|:::||: .|..||..||:|..|:|
Zfish    12 RTGAETLGVM---LGADCAHHQ-------SVCEGCHRPISDRFLLRM-NDSSWHEECLQCSVCQQ 65

  Fly    88 FLDESCTCFVRDGKTYCKRDYVRLFGTKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLL 152
            .|  :.:|:.||.|.|||.||.:||.|||..|....|..:.||||...::|:.||.|..|.|:|.
Zfish    66 LL--TMSCYSRDHKLYCKHDYQQLFATKCSGCLEKISPTELVMRALESVYHLSCFCCCVCERRLC 128

  Fly   153 PGDEFALRDAGALYCKEDHDVLEKSSQSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSD 217
            .||||.|:: |.|.||.|:                |...:::|.:.::::.|.:...........
Zfish   129 KGDEFVLKE-GQLLCKTDY----------------EREKDLASPDLSDSDKSEDEDLDVKPEKGA 176

  Fly   218 SGSESGSHKSIRDKRPSGPSDGKPTRVRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSP 282
            .|...||..| :|.|       :|.|.||:|..:|....:..:..:.:|...::|.|...|.||.
Zfish   177 GGQGKGSDDS-KDPR-------RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV 233

  Fly   283 RVIRVWFQNKRCKDKKKTIQMKLQMQQEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQT 347
            ||::|||||:|.| .||..:.:.|.|:::..::||...|.
Zfish   234 RVVQVWFQNQRAK-MKKLARRQQQQQEQQNSQRLGQDVMS------------------------- 272

  Fly   348 YQPPWKALSDFALHADLDSNGAINTHTPAFQQLVNQMHGYDLNGMPILPPHPH---SHPAQG--- 406
                                          .::.|.|..|    .|:.||.||   |..:.|
Zfish   273 ------------------------------SRMENLMSSY----TPLAPPPPHALVSMESSGYST 303

  Fly   407 PPHQHPPPPGGPHNHQNQQPNQQPGGSSLDSGITSHHHPDSTDSYVTYLESDDKSKLALTP---S 468
            .|.|           |...|.|.||         .|.:|...||....::| |.|..:|:.   |
Zfish   304 DPFQ-----------QGLTPPQMPG---------DHMNPYGNDSIFHDIDS-DTSLTSLSDCFMS 347

  Fly   469 SSSSASAGTSISSP 482
            :|.:|:..:.:.:|
Zfish   348 ASDAAALQSRVGNP 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752	23/53 (43%)
		LIM2_Isl	116..171	CDD:188760	23/54 (43%)
		HOX	241..297	CDD:197696	21/55 (38%)
lmx1ba	NP_001349521.1	LIM1_Lmx1b	33..85	CDD:188757	24/54 (44%)
		LIM	92..146	CDD:413332	23/54 (43%)
		Homeodomain	193..249	CDD:459649	20/56 (36%)