Protein Alignment tup and lhx8

DIOPT Version :10

• Sequence 1: NP_476775.1
• Gene: tup / 35147
• FlyBaseID: FBgn0003896
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: XP_012816489.1
• Gene: lhx8 / 548653
• XenbaseID: XB-GENE-494997
• Length: 385
• Species: Xenopus tropicalis
• Alignment Length: 362
• Identity: 106/362 - (29%)
• Similarity: 153/362 - (42%)
• Gaps: 84/362 - (23%)

  Fly    49 QRLSHCVGCGGQIHDQYILRVAPDLEWHAACLKCQECRQFLDESCTCFVRDGKTYCKRDYVRLFG 113
            |..|.|..||.:|.|:|:|:| .||.||..||.|..||..|....:|:::|...|||.||.|.:|
 Frog    99 QGKSVCSNCGLEIVDKYLLKV-NDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIYCKLDYFRRYG 162

  Fly   114 TKCDKCGNSFSKNDFVMRAKTKIFHIECFRCSACARQLLPGDEFALRDAGALYCKEDHDVLEKSS 178
            |:|.:||......|:|.|||..::|:.||.|.:|.|||..|:||||.:...| |:..:|.:
 Frog   163 TRCSRCGRHIHATDWVRRAKGNVYHLACFACYSCKRQLSTGEEFALVEEKVL-CRVHYDCM---- 222

  Fly   179 QSSLTSSSVESNNNISSSNNNNTNLSNNNHSSELGSMSDSGSESGSHKSIRDKRPSGPSDGKPTR 243
                             .:|....:.|.|..|..|::.       :.:.|...:|:       .|
 Frog   223 -----------------LDNLKRAVENGNRVSVEGALL-------TEQDINQPKPA-------KR 256

  Fly   244 VRTVLNEKQLHTLRTCYNANPRPDALMKEQLVEMTSLSPRVIRVWFQNKRCKDKKKTIQMKLQMQ 308
            .||.....||..::..:..:..|||...::|.|.|.||.|||:|||||.|.:.||
 Frog   257 ARTSFTADQLQVMQAQFAQDNNPDAQTLQKLSERTGLSRRVIQVWFQNCRARHKK---------- 311

  Fly   309 QEKEGRKLGYGAMQGIPMIASSPVRHDSPLNLQGLDVQTYQP---PWKALSDFALHADLDSNGAI 370
                  .:........|:....|.|...|: |:.:....|.|   |...    |||:.:|:
 Frog   312 ------HVSPNHSSTTPVTTVQPSRLSPPM-LEEMTYSAYVPQDGPMLT----ALHSYMDA---- 361

  Fly   371 NTHTPAFQQLVNQMHGYDLNGMPILPPH-----PHSH 402
              |:|.            ..|:..|.||     |.||
 Frog   362 --HSPT------------ALGLQSLLPHSMTQLPISH 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tup	NP_476775.1	LIM1_Isl	54..108	CDD:188752	23/53 (43%)
		LIM2_Isl	116..171	CDD:188760	23/54 (43%)
		HOX	241..297	CDD:197696	22/55 (40%)
lhx8	XP_012816489.1	LIM1_Lhx7_Lhx8	103..158	CDD:188767	24/55 (44%)
		LIM2_Lhx7_Lhx8	165..219	CDD:188769	23/54 (43%)
		Homeodomain	255..311	CDD:459649	22/55 (40%)